Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients

Detalhes bibliográficos
Autor(a) principal: Hugo Senra
Data de Publicação: 2022
Outros Autores: Hernandez-Moreno, Laura, Moreno, Natacha, Macedo, António Filipe
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/103495
https://doi.org/10.1038/s41598-022-06252-1
Resumo: The current study examines the potential moderating effect of depression and anxiety on the relationship between visual acuity and health-related quality of life in patients with chronic eye diseases. Of the 71 patients, 37 (52%) were female and 34 (48%) were male, age (mean ± SD) was 69 ± 12 years. A significant multivariate regression model was found for patients' health-related quality of life (EQ-5D-5L index) (R2 = 0.43, p < 0.001), in which visual acuity (logMAR) (p < 0.001), anxiety (HADS-A) (p = 0.007), and age of diagnosis (p = 0.04)  were independently associated with health-related quality of life (EQ-5D-5L). The moderation model for anxiety (R2 = 0.47, F = 5.91, p < 0.001) revealed a significant interaction of visual acuity and levels of anxiety in relation to health-related quality of life. Conditional effects analysis suggested that higher logMAR values (which indicate more vision loss) were associated with lower EQ-5D-5L index (indicating worse health-related quality of life), this relationship being stronger (even more negative), when levels of anxiety are high. Clinical and rehabilitation services providing care for chronic eye disease patients should include regular checks for patients' levels of anxiety, even in patients who still have preserved visual acuity, to help preventing a synergistic source of long-term poor quality of life and disability.
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spelling Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patientsAgedAged, 80 and overChronic DiseaseEye DiseasesFemaleHumansMaleMiddle AgedPatient AcuityAnxietyQuality of LifeVisual AcuityThe current study examines the potential moderating effect of depression and anxiety on the relationship between visual acuity and health-related quality of life in patients with chronic eye diseases. Of the 71 patients, 37 (52%) were female and 34 (48%) were male, age (mean ± SD) was 69 ± 12 years. A significant multivariate regression model was found for patients' health-related quality of life (EQ-5D-5L index) (R2 = 0.43, p < 0.001), in which visual acuity (logMAR) (p < 0.001), anxiety (HADS-A) (p = 0.007), and age of diagnosis (p = 0.04)  were independently associated with health-related quality of life (EQ-5D-5L). The moderation model for anxiety (R2 = 0.47, F = 5.91, p < 0.001) revealed a significant interaction of visual acuity and levels of anxiety in relation to health-related quality of life. Conditional effects analysis suggested that higher logMAR values (which indicate more vision loss) were associated with lower EQ-5D-5L index (indicating worse health-related quality of life), this relationship being stronger (even more negative), when levels of anxiety are high. Clinical and rehabilitation services providing care for chronic eye disease patients should include regular checks for patients' levels of anxiety, even in patients who still have preserved visual acuity, to help preventing a synergistic source of long-term poor quality of life and disability.Nature Research2022info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/103495http://hdl.handle.net/10316/103495https://doi.org/10.1038/s41598-022-06252-1eng2045-2322Hugo SenraHernandez-Moreno, LauraMoreno, NatachaMacedo, António Filipeinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-16T21:35:52Zoai:estudogeral.uc.pt:10316/103495Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:20:19.262883Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients
title Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients
spellingShingle Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients
Hugo Senra
Aged
Aged, 80 and over
Chronic Disease
Eye Diseases
Female
Humans
Male
Middle Aged
Patient Acuity
Anxiety
Quality of Life
Visual Acuity
title_short Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients
title_full Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients
title_fullStr Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients
title_full_unstemmed Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients
title_sort Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients
author Hugo Senra
author_facet Hugo Senra
Hernandez-Moreno, Laura
Moreno, Natacha
Macedo, António Filipe
author_role author
author2 Hernandez-Moreno, Laura
Moreno, Natacha
Macedo, António Filipe
author2_role author
author
author
dc.contributor.author.fl_str_mv Hugo Senra
Hernandez-Moreno, Laura
Moreno, Natacha
Macedo, António Filipe
dc.subject.por.fl_str_mv Aged
Aged, 80 and over
Chronic Disease
Eye Diseases
Female
Humans
Male
Middle Aged
Patient Acuity
Anxiety
Quality of Life
Visual Acuity
topic Aged
Aged, 80 and over
Chronic Disease
Eye Diseases
Female
Humans
Male
Middle Aged
Patient Acuity
Anxiety
Quality of Life
Visual Acuity
description The current study examines the potential moderating effect of depression and anxiety on the relationship between visual acuity and health-related quality of life in patients with chronic eye diseases. Of the 71 patients, 37 (52%) were female and 34 (48%) were male, age (mean ± SD) was 69 ± 12 years. A significant multivariate regression model was found for patients' health-related quality of life (EQ-5D-5L index) (R2 = 0.43, p < 0.001), in which visual acuity (logMAR) (p < 0.001), anxiety (HADS-A) (p = 0.007), and age of diagnosis (p = 0.04)  were independently associated with health-related quality of life (EQ-5D-5L). The moderation model for anxiety (R2 = 0.47, F = 5.91, p < 0.001) revealed a significant interaction of visual acuity and levels of anxiety in relation to health-related quality of life. Conditional effects analysis suggested that higher logMAR values (which indicate more vision loss) were associated with lower EQ-5D-5L index (indicating worse health-related quality of life), this relationship being stronger (even more negative), when levels of anxiety are high. Clinical and rehabilitation services providing care for chronic eye disease patients should include regular checks for patients' levels of anxiety, even in patients who still have preserved visual acuity, to help preventing a synergistic source of long-term poor quality of life and disability.
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/103495
http://hdl.handle.net/10316/103495
https://doi.org/10.1038/s41598-022-06252-1
url http://hdl.handle.net/10316/103495
https://doi.org/10.1038/s41598-022-06252-1
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2045-2322
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Nature Research
publisher.none.fl_str_mv Nature Research
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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