Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/103495 https://doi.org/10.1038/s41598-022-06252-1 |
Resumo: | The current study examines the potential moderating effect of depression and anxiety on the relationship between visual acuity and health-related quality of life in patients with chronic eye diseases. Of the 71 patients, 37 (52%) were female and 34 (48%) were male, age (mean ± SD) was 69 ± 12 years. A significant multivariate regression model was found for patients' health-related quality of life (EQ-5D-5L index) (R2 = 0.43, p < 0.001), in which visual acuity (logMAR) (p < 0.001), anxiety (HADS-A) (p = 0.007), and age of diagnosis (p = 0.04) were independently associated with health-related quality of life (EQ-5D-5L). The moderation model for anxiety (R2 = 0.47, F = 5.91, p < 0.001) revealed a significant interaction of visual acuity and levels of anxiety in relation to health-related quality of life. Conditional effects analysis suggested that higher logMAR values (which indicate more vision loss) were associated with lower EQ-5D-5L index (indicating worse health-related quality of life), this relationship being stronger (even more negative), when levels of anxiety are high. Clinical and rehabilitation services providing care for chronic eye disease patients should include regular checks for patients' levels of anxiety, even in patients who still have preserved visual acuity, to help preventing a synergistic source of long-term poor quality of life and disability. |
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Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patientsAgedAged, 80 and overChronic DiseaseEye DiseasesFemaleHumansMaleMiddle AgedPatient AcuityAnxietyQuality of LifeVisual AcuityThe current study examines the potential moderating effect of depression and anxiety on the relationship between visual acuity and health-related quality of life in patients with chronic eye diseases. Of the 71 patients, 37 (52%) were female and 34 (48%) were male, age (mean ± SD) was 69 ± 12 years. A significant multivariate regression model was found for patients' health-related quality of life (EQ-5D-5L index) (R2 = 0.43, p < 0.001), in which visual acuity (logMAR) (p < 0.001), anxiety (HADS-A) (p = 0.007), and age of diagnosis (p = 0.04) were independently associated with health-related quality of life (EQ-5D-5L). The moderation model for anxiety (R2 = 0.47, F = 5.91, p < 0.001) revealed a significant interaction of visual acuity and levels of anxiety in relation to health-related quality of life. Conditional effects analysis suggested that higher logMAR values (which indicate more vision loss) were associated with lower EQ-5D-5L index (indicating worse health-related quality of life), this relationship being stronger (even more negative), when levels of anxiety are high. Clinical and rehabilitation services providing care for chronic eye disease patients should include regular checks for patients' levels of anxiety, even in patients who still have preserved visual acuity, to help preventing a synergistic source of long-term poor quality of life and disability.Nature Research2022info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/103495http://hdl.handle.net/10316/103495https://doi.org/10.1038/s41598-022-06252-1eng2045-2322Hugo SenraHernandez-Moreno, LauraMoreno, NatachaMacedo, António Filipeinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-16T21:35:52Zoai:estudogeral.uc.pt:10316/103495Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:20:19.262883Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients |
title |
Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients |
spellingShingle |
Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients Hugo Senra Aged Aged, 80 and over Chronic Disease Eye Diseases Female Humans Male Middle Aged Patient Acuity Anxiety Quality of Life Visual Acuity |
title_short |
Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients |
title_full |
Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients |
title_fullStr |
Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients |
title_full_unstemmed |
Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients |
title_sort |
Anxiety levels moderate the association between visual acuity and health-related quality of life in chronic eye disease patients |
author |
Hugo Senra |
author_facet |
Hugo Senra Hernandez-Moreno, Laura Moreno, Natacha Macedo, António Filipe |
author_role |
author |
author2 |
Hernandez-Moreno, Laura Moreno, Natacha Macedo, António Filipe |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Hugo Senra Hernandez-Moreno, Laura Moreno, Natacha Macedo, António Filipe |
dc.subject.por.fl_str_mv |
Aged Aged, 80 and over Chronic Disease Eye Diseases Female Humans Male Middle Aged Patient Acuity Anxiety Quality of Life Visual Acuity |
topic |
Aged Aged, 80 and over Chronic Disease Eye Diseases Female Humans Male Middle Aged Patient Acuity Anxiety Quality of Life Visual Acuity |
description |
The current study examines the potential moderating effect of depression and anxiety on the relationship between visual acuity and health-related quality of life in patients with chronic eye diseases. Of the 71 patients, 37 (52%) were female and 34 (48%) were male, age (mean ± SD) was 69 ± 12 years. A significant multivariate regression model was found for patients' health-related quality of life (EQ-5D-5L index) (R2 = 0.43, p < 0.001), in which visual acuity (logMAR) (p < 0.001), anxiety (HADS-A) (p = 0.007), and age of diagnosis (p = 0.04) were independently associated with health-related quality of life (EQ-5D-5L). The moderation model for anxiety (R2 = 0.47, F = 5.91, p < 0.001) revealed a significant interaction of visual acuity and levels of anxiety in relation to health-related quality of life. Conditional effects analysis suggested that higher logMAR values (which indicate more vision loss) were associated with lower EQ-5D-5L index (indicating worse health-related quality of life), this relationship being stronger (even more negative), when levels of anxiety are high. Clinical and rehabilitation services providing care for chronic eye disease patients should include regular checks for patients' levels of anxiety, even in patients who still have preserved visual acuity, to help preventing a synergistic source of long-term poor quality of life and disability. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/103495 http://hdl.handle.net/10316/103495 https://doi.org/10.1038/s41598-022-06252-1 |
url |
http://hdl.handle.net/10316/103495 https://doi.org/10.1038/s41598-022-06252-1 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2045-2322 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Nature Research |
publisher.none.fl_str_mv |
Nature Research |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799134095909847040 |