Treatment adherence in schizophrenia: a literature review
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.51338/rppsm.2018.v1.i3.83 |
Resumo: | Abstract: Introduction: Evaluating adherence to treatment with antipsychotic agents in patients with schizophrenia is a challenge for any psychiatric doctor, given its inherent subjectivity. Despite this, nonadherence to treatment is prejudicial to the clinical course of the disease, resulting in a greater risk of acute exacerbations of illness and hospital admissions. The aim of this study is to review the current literature on factors that influence adherence to antipsychotic treatment in patients with schizophrenia. Methods: The literature, written in English between 2006 and 2016 and available in full in PubMed/MEDLINE, evaluating potential risk factors for treatment compliance in adult patients (over 18 years of age) with schizophrenia, was reviewed by searching on the keywords: adherence, nonadherence, compliance, noncompliance, schizophrenia, psychosis, antipsychotic, neuroleptic. Results: Thirty-nine studies were included in the final review. The average level of treatment adherence was 32%. The following risk factors for nonadherence to treatment were identified: young age, substance abuse, psychotic psychopathology present, absence of insight into the disorder and the need for treatment, negative attitudes to treatment, poor doctor-patient relationship and lack of social and family support. Conclusions: Interventions aimed at improving treatment adherence must be individualised for each patient, on the basis of a full clinical history, so that all the individual aspects contributing to this variable can be appropriately assessed. |
id |
RCAP_dc303c5b0fbb79dd47e32f5775c59f91 |
---|---|
oai_identifier_str |
oai:ojs.www.revistapsiquiatria.pt:article/83 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Treatment adherence in schizophrenia: a literature reviewAdesão à terapêutica nos doentes com esquizofrenia: uma revisão da literaturaadherencenonadherencecompliancenoncomplianceschizophreniapsychosisantipsychoticneurolep.adesão à terapêuticaantipsicóticospsicoseesquizofrenia.Abstract: Introduction: Evaluating adherence to treatment with antipsychotic agents in patients with schizophrenia is a challenge for any psychiatric doctor, given its inherent subjectivity. Despite this, nonadherence to treatment is prejudicial to the clinical course of the disease, resulting in a greater risk of acute exacerbations of illness and hospital admissions. The aim of this study is to review the current literature on factors that influence adherence to antipsychotic treatment in patients with schizophrenia. Methods: The literature, written in English between 2006 and 2016 and available in full in PubMed/MEDLINE, evaluating potential risk factors for treatment compliance in adult patients (over 18 years of age) with schizophrenia, was reviewed by searching on the keywords: adherence, nonadherence, compliance, noncompliance, schizophrenia, psychosis, antipsychotic, neuroleptic. Results: Thirty-nine studies were included in the final review. The average level of treatment adherence was 32%. The following risk factors for nonadherence to treatment were identified: young age, substance abuse, psychotic psychopathology present, absence of insight into the disorder and the need for treatment, negative attitudes to treatment, poor doctor-patient relationship and lack of social and family support. Conclusions: Interventions aimed at improving treatment adherence must be individualised for each patient, on the basis of a full clinical history, so that all the individual aspects contributing to this variable can be appropriately assessed.Resumo: Introdução: Avaliar a adesão ao tratamento com agentes antipsicóticos em doentes com esquizofrenia é um desafio para qualquer médico psiquiatra, dada a subjetividade inerente ao tema. Apesar disso, a falta de adesão à terapêutica é prejudicial para o curso clínico da doença, resultando num risco aumentado de agudizações da doença e de internamentos hospitalares. O objetivo do presente estudo é rever a literatura corrente relativa aos fatores que influenciam a adesão ao tratamento antipsicótico em doentes com esquizofrenia. Métodos: Foi revista a literatura escrita em inglês entre 2006 e 2016 integralmente disponível no PubMed/MEDLINE que avaliasse potenciais fatores de risco para a adesão ao tratamento em doentes adultos (com mais de 18 anos) com esquizofrenia, através das palavras-chave: adherence, nonadherence, compliance, noncompliance, schizophrenia, psychosis, antipsychotic, neuroleptic. Resultados: Foram incluídos 39 estudos na revisão final. A média dos níveis de adesão ao tratamento foi de 32%. Foram identificados os seguintes fatores de risco para a falta de adesão ao tratamento: idade jovem, abuso de substâncias, psicopatologia psicótica presente, ausência de insight sobre a doença e a necessidade de tratamento, atitudes negativas perante o tratamento, relação médico-doente de má qualidade ou falta de apoio social e familiar. Conclusões: As intervenções direcionadas para melhorar a adesão à terapêutica devem ser individualizadas para cada doente, baseadas numa história clínica completa, para que todos os aspetos individuais que contribuam para esta variável possam ser convenientemente avaliados.Sociedade Portuguesa de Psiquiatria e Saúde Mental2018-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://doi.org/10.51338/rppsm.2018.v1.i3.83oai:ojs.www.revistapsiquiatria.pt:article/83Revista Portuguesa de Psiquiatria e Saúde Mental; No. 3 (2018): Revista Portuguesa de Psiquiatria e Saúde Mental; 25-33Revista Portuguesa de Psiquiatria e Saúde Mental; N.º 3 (2018): Revista Portuguesa de Psiquiatria e Saúde Mental; 25-332184-54172184-5522reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporenghttps://www.revistapsiquiatria.pt/index.php/sppsm/article/view/83https://doi.org/10.51338/rppsm.2018.v1.i3.83https://www.revistapsiquiatria.pt/index.php/sppsm/article/view/83/42https://www.revistapsiquiatria.pt/index.php/sppsm/article/view/83/43Direitos de Autor (c) 2018 Revista Portuguesa de Psiquiatria e Saúde Mentalinfo:eu-repo/semantics/openAccessDescalço, NelsonAfonso, Pedro2022-09-06T09:37:38Zoai:ojs.www.revistapsiquiatria.pt:article/83Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:37:10.751873Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Treatment adherence in schizophrenia: a literature review Adesão à terapêutica nos doentes com esquizofrenia: uma revisão da literatura |
title |
Treatment adherence in schizophrenia: a literature review |
spellingShingle |
Treatment adherence in schizophrenia: a literature review Descalço, Nelson adherence nonadherence compliance noncompliance schizophrenia psychosis antipsychotic neurolep. adesão à terapêutica antipsicóticos psicose esquizofrenia. |
title_short |
Treatment adherence in schizophrenia: a literature review |
title_full |
Treatment adherence in schizophrenia: a literature review |
title_fullStr |
Treatment adherence in schizophrenia: a literature review |
title_full_unstemmed |
Treatment adherence in schizophrenia: a literature review |
title_sort |
Treatment adherence in schizophrenia: a literature review |
author |
Descalço, Nelson |
author_facet |
Descalço, Nelson Afonso, Pedro |
author_role |
author |
author2 |
Afonso, Pedro |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Descalço, Nelson Afonso, Pedro |
dc.subject.por.fl_str_mv |
adherence nonadherence compliance noncompliance schizophrenia psychosis antipsychotic neurolep. adesão à terapêutica antipsicóticos psicose esquizofrenia. |
topic |
adherence nonadherence compliance noncompliance schizophrenia psychosis antipsychotic neurolep. adesão à terapêutica antipsicóticos psicose esquizofrenia. |
description |
Abstract: Introduction: Evaluating adherence to treatment with antipsychotic agents in patients with schizophrenia is a challenge for any psychiatric doctor, given its inherent subjectivity. Despite this, nonadherence to treatment is prejudicial to the clinical course of the disease, resulting in a greater risk of acute exacerbations of illness and hospital admissions. The aim of this study is to review the current literature on factors that influence adherence to antipsychotic treatment in patients with schizophrenia. Methods: The literature, written in English between 2006 and 2016 and available in full in PubMed/MEDLINE, evaluating potential risk factors for treatment compliance in adult patients (over 18 years of age) with schizophrenia, was reviewed by searching on the keywords: adherence, nonadherence, compliance, noncompliance, schizophrenia, psychosis, antipsychotic, neuroleptic. Results: Thirty-nine studies were included in the final review. The average level of treatment adherence was 32%. The following risk factors for nonadherence to treatment were identified: young age, substance abuse, psychotic psychopathology present, absence of insight into the disorder and the need for treatment, negative attitudes to treatment, poor doctor-patient relationship and lack of social and family support. Conclusions: Interventions aimed at improving treatment adherence must be individualised for each patient, on the basis of a full clinical history, so that all the individual aspects contributing to this variable can be appropriately assessed. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.51338/rppsm.2018.v1.i3.83 oai:ojs.www.revistapsiquiatria.pt:article/83 |
url |
https://doi.org/10.51338/rppsm.2018.v1.i3.83 |
identifier_str_mv |
oai:ojs.www.revistapsiquiatria.pt:article/83 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://www.revistapsiquiatria.pt/index.php/sppsm/article/view/83 https://doi.org/10.51338/rppsm.2018.v1.i3.83 https://www.revistapsiquiatria.pt/index.php/sppsm/article/view/83/42 https://www.revistapsiquiatria.pt/index.php/sppsm/article/view/83/43 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2018 Revista Portuguesa de Psiquiatria e Saúde Mental info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos de Autor (c) 2018 Revista Portuguesa de Psiquiatria e Saúde Mental |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Psiquiatria e Saúde Mental |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Psiquiatria e Saúde Mental |
dc.source.none.fl_str_mv |
Revista Portuguesa de Psiquiatria e Saúde Mental; No. 3 (2018): Revista Portuguesa de Psiquiatria e Saúde Mental; 25-33 Revista Portuguesa de Psiquiatria e Saúde Mental; N.º 3 (2018): Revista Portuguesa de Psiquiatria e Saúde Mental; 25-33 2184-5417 2184-5522 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799130237741563904 |