New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.

Detalhes bibliográficos
Autor(a) principal: Salgueiro, Patrícia
Data de Publicação: 2013
Outros Autores: Moreno, Marta, Simard, Frederic, O'Brochta,  David, Pinto, João Pedro Soares da Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/116972
Resumo: Transposable elements (TEs) are mobile portions of DNA that are able to replicate and spread in the genome of many organisms. TEs can be used as a means to insert transgenes in insects, being stably inherited throughout generations. Anopheles gambiae is the main vector of human malaria in Sub-Saharan Africa. Given the extraordinary burden this disease imposes, the mosquito became a choice target for genetic control approaches with the purpose of reducing malaria transmission. In this study, we investigated the abundance and distribution of Herves TE in An. gambiae s.s. from Cameroon and four islands in the Gulf of Guinea, in order to determine their genetic structure. We have detected a population subdivision between Equatorial Guinea islands and the islands of São Tomé, Príncipe and mainland. This partitioning associates more with political rather than geographic boundaries, possibly reflecting different mainland source populations colonizing the islands.
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spelling New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.GeneticsInsect ScienceEcology, Evolution, Behavior and SystematicsInfectious DiseasesSDG 3 - Good Health and Well-beingTransposable elements (TEs) are mobile portions of DNA that are able to replicate and spread in the genome of many organisms. TEs can be used as a means to insert transgenes in insects, being stably inherited throughout generations. Anopheles gambiae is the main vector of human malaria in Sub-Saharan Africa. Given the extraordinary burden this disease imposes, the mosquito became a choice target for genetic control approaches with the purpose of reducing malaria transmission. In this study, we investigated the abundance and distribution of Herves TE in An. gambiae s.s. from Cameroon and four islands in the Gulf of Guinea, in order to determine their genetic structure. We have detected a population subdivision between Equatorial Guinea islands and the islands of São Tomé, Príncipe and mainland. This partitioning associates more with political rather than geographic boundaries, possibly reflecting different mainland source populations colonizing the islands.Instituto de Higiene e Medicina Tropical (IHMT)Centro de Malária e outras Doenças Tropicais (CMDT)RUNSalgueiro, PatríciaMoreno, MartaSimard, FredericO'Brochta,  DavidPinto, João Pedro Soares da Silva2021-05-04T22:32:45Z2013-01-012013-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/116972engPURE: 261647https://doi.org/10.1371/journal.pone.0062964info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:59:54Zoai:run.unl.pt:10362/116972Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:43:24.754853Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.
title New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.
spellingShingle New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.
Salgueiro, Patrícia
Genetics
Insect Science
Ecology, Evolution, Behavior and Systematics
Infectious Diseases
SDG 3 - Good Health and Well-being
title_short New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.
title_full New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.
title_fullStr New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.
title_full_unstemmed New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.
title_sort New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.
author Salgueiro, Patrícia
author_facet Salgueiro, Patrícia
Moreno, Marta
Simard, Frederic
O'Brochta,  David
Pinto, João Pedro Soares da Silva
author_role author
author2 Moreno, Marta
Simard, Frederic
O'Brochta,  David
Pinto, João Pedro Soares da Silva
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Instituto de Higiene e Medicina Tropical (IHMT)
Centro de Malária e outras Doenças Tropicais (CMDT)
RUN
dc.contributor.author.fl_str_mv Salgueiro, Patrícia
Moreno, Marta
Simard, Frederic
O'Brochta,  David
Pinto, João Pedro Soares da Silva
dc.subject.por.fl_str_mv Genetics
Insect Science
Ecology, Evolution, Behavior and Systematics
Infectious Diseases
SDG 3 - Good Health and Well-being
topic Genetics
Insect Science
Ecology, Evolution, Behavior and Systematics
Infectious Diseases
SDG 3 - Good Health and Well-being
description Transposable elements (TEs) are mobile portions of DNA that are able to replicate and spread in the genome of many organisms. TEs can be used as a means to insert transgenes in insects, being stably inherited throughout generations. Anopheles gambiae is the main vector of human malaria in Sub-Saharan Africa. Given the extraordinary burden this disease imposes, the mosquito became a choice target for genetic control approaches with the purpose of reducing malaria transmission. In this study, we investigated the abundance and distribution of Herves TE in An. gambiae s.s. from Cameroon and four islands in the Gulf of Guinea, in order to determine their genetic structure. We have detected a population subdivision between Equatorial Guinea islands and the islands of São Tomé, Príncipe and mainland. This partitioning associates more with political rather than geographic boundaries, possibly reflecting different mainland source populations colonizing the islands.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01
2013-01-01T00:00:00Z
2021-05-04T22:32:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/116972
url http://hdl.handle.net/10362/116972
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv PURE: 261647
https://doi.org/10.1371/journal.pone.0062964
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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