Anxiety and/or depression: which symptoms contribute to adverse clinical outcomes after amputation?

• Autor(a) principal: Pedras, Carla Susana Abreu
• Data de Publicação: 2020
• Outros Autores: Meira-Machado, Luís, Couto de Carvalho, André, Carvalho, Rui, Pereira, M. Graça
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://hdl.handle.net/1822/69691
• topic: Diabetic foot ulcer; Amputation; Reamputation; Healing; Depression; Anxiety; Mortality; Ciências Sociais::Psicologia; Social Sciences; Saúde de qualidade

Background: One of the most serious complications of diabetes mellitus (DM) is a diabetic foot ulcer (DFU), with lower extremity amputation (LEA). Aims: This study aims to explore the role of anxiety and depression on mortality, reamputation and healing, after a LEA due to DFU. Methods: A sample of 149 patients with DFU who underwent LEA answered the Hospital Anxiety and Depression Scale and a sociodemographic and clinical questionnaire. This is a longitudinal and multicenter study with four assessment moments that used Cox proportional hazards models adjusted for demographic and clinical variables. Results: Rate of mortality, reamputation and healing, 10 months after LEA were 9.4%, 27.5% and 61.7%, respectively. Anxiety, at baseline, was negatively associated with healing. However, depression was not an independent predictor of mortality. None of the psychological factors was associated with reamputation. Conclusion: Results highlight the significant contribution of anxiety symptoms at pre-surgery, to healing after a LEA. Suggestions for psychological interventions are made.