Fluid Overload in Pediatric Severe Trauma

Detalhes bibliográficos
Autor(a) principal: Ana Patrícia de Matos Coelho
Data de Publicação: 2022
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/142120
Resumo: Background and objective: Trauma is a leading cause of pediatric mortality and potential years of life lost in the developed world. Critically ill children frequently achieve a net positive fluid balance and fluid overload is associated with substantial morbidity and mortality in pediatrics. This study investigated the association between fluid balance status and clinical outcomes in pediatric severe trauma patients. Methods: This is a unicentric, observational retrospective study. Sixty-six children with severe trauma admitted to a tertiary hospital PICU over a 3-year period were included. Electronic medical records were reviewed. Fluid balance in the first 24 hours of PICU admission was calculated. Results: Males comprised 56% of the sample and median age was 12.2 years. Forty-one (62,1%) suffered polytrauma, 32 of these with traumatic brain injury (TBI), and 25 had isolated TBI. Seventeen (25,7%) patients had early fluid overload (FO). Early FO was not significantly associated with mortality, acute kidney injury, PICU length-of-stay, duration of mechanical ventilation and vasoactive support. TBI and polytrauma patients did not have increased risk of neither of these outcomes. Conclusions: Unlike other ICU cohorts, fluid overload does not appear to be associated with worse clinical outcomes in severe trauma patients.
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spelling Fluid Overload in Pediatric Severe TraumaMedicina clínicaClinical medicineBackground and objective: Trauma is a leading cause of pediatric mortality and potential years of life lost in the developed world. Critically ill children frequently achieve a net positive fluid balance and fluid overload is associated with substantial morbidity and mortality in pediatrics. This study investigated the association between fluid balance status and clinical outcomes in pediatric severe trauma patients. Methods: This is a unicentric, observational retrospective study. Sixty-six children with severe trauma admitted to a tertiary hospital PICU over a 3-year period were included. Electronic medical records were reviewed. Fluid balance in the first 24 hours of PICU admission was calculated. Results: Males comprised 56% of the sample and median age was 12.2 years. Forty-one (62,1%) suffered polytrauma, 32 of these with traumatic brain injury (TBI), and 25 had isolated TBI. Seventeen (25,7%) patients had early fluid overload (FO). Early FO was not significantly associated with mortality, acute kidney injury, PICU length-of-stay, duration of mechanical ventilation and vasoactive support. TBI and polytrauma patients did not have increased risk of neither of these outcomes. Conclusions: Unlike other ICU cohorts, fluid overload does not appear to be associated with worse clinical outcomes in severe trauma patients.2022-05-162022-05-16T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://hdl.handle.net/10216/142120TID:203176502engAna Patrícia de Matos Coelhoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T13:47:52Zoai:repositorio-aberto.up.pt:10216/142120Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:47:52.117760Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Fluid Overload in Pediatric Severe Trauma
title Fluid Overload in Pediatric Severe Trauma
spellingShingle Fluid Overload in Pediatric Severe Trauma
Ana Patrícia de Matos Coelho
Medicina clínica
Clinical medicine
title_short Fluid Overload in Pediatric Severe Trauma
title_full Fluid Overload in Pediatric Severe Trauma
title_fullStr Fluid Overload in Pediatric Severe Trauma
title_full_unstemmed Fluid Overload in Pediatric Severe Trauma
title_sort Fluid Overload in Pediatric Severe Trauma
author Ana Patrícia de Matos Coelho
author_facet Ana Patrícia de Matos Coelho
author_role author
dc.contributor.author.fl_str_mv Ana Patrícia de Matos Coelho
dc.subject.por.fl_str_mv Medicina clínica
Clinical medicine
topic Medicina clínica
Clinical medicine
description Background and objective: Trauma is a leading cause of pediatric mortality and potential years of life lost in the developed world. Critically ill children frequently achieve a net positive fluid balance and fluid overload is associated with substantial morbidity and mortality in pediatrics. This study investigated the association between fluid balance status and clinical outcomes in pediatric severe trauma patients. Methods: This is a unicentric, observational retrospective study. Sixty-six children with severe trauma admitted to a tertiary hospital PICU over a 3-year period were included. Electronic medical records were reviewed. Fluid balance in the first 24 hours of PICU admission was calculated. Results: Males comprised 56% of the sample and median age was 12.2 years. Forty-one (62,1%) suffered polytrauma, 32 of these with traumatic brain injury (TBI), and 25 had isolated TBI. Seventeen (25,7%) patients had early fluid overload (FO). Early FO was not significantly associated with mortality, acute kidney injury, PICU length-of-stay, duration of mechanical ventilation and vasoactive support. TBI and polytrauma patients did not have increased risk of neither of these outcomes. Conclusions: Unlike other ICU cohorts, fluid overload does not appear to be associated with worse clinical outcomes in severe trauma patients.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-16
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