Fluid Overload in Pediatric Severe Trauma
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Tipo de documento: | Dissertação |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/10216/142120 |
Resumo: | Background and objective: Trauma is a leading cause of pediatric mortality and potential years of life lost in the developed world. Critically ill children frequently achieve a net positive fluid balance and fluid overload is associated with substantial morbidity and mortality in pediatrics. This study investigated the association between fluid balance status and clinical outcomes in pediatric severe trauma patients. Methods: This is a unicentric, observational retrospective study. Sixty-six children with severe trauma admitted to a tertiary hospital PICU over a 3-year period were included. Electronic medical records were reviewed. Fluid balance in the first 24 hours of PICU admission was calculated. Results: Males comprised 56% of the sample and median age was 12.2 years. Forty-one (62,1%) suffered polytrauma, 32 of these with traumatic brain injury (TBI), and 25 had isolated TBI. Seventeen (25,7%) patients had early fluid overload (FO). Early FO was not significantly associated with mortality, acute kidney injury, PICU length-of-stay, duration of mechanical ventilation and vasoactive support. TBI and polytrauma patients did not have increased risk of neither of these outcomes. Conclusions: Unlike other ICU cohorts, fluid overload does not appear to be associated with worse clinical outcomes in severe trauma patients. |
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Fluid Overload in Pediatric Severe TraumaMedicina clínicaClinical medicineBackground and objective: Trauma is a leading cause of pediatric mortality and potential years of life lost in the developed world. Critically ill children frequently achieve a net positive fluid balance and fluid overload is associated with substantial morbidity and mortality in pediatrics. This study investigated the association between fluid balance status and clinical outcomes in pediatric severe trauma patients. Methods: This is a unicentric, observational retrospective study. Sixty-six children with severe trauma admitted to a tertiary hospital PICU over a 3-year period were included. Electronic medical records were reviewed. Fluid balance in the first 24 hours of PICU admission was calculated. Results: Males comprised 56% of the sample and median age was 12.2 years. Forty-one (62,1%) suffered polytrauma, 32 of these with traumatic brain injury (TBI), and 25 had isolated TBI. Seventeen (25,7%) patients had early fluid overload (FO). Early FO was not significantly associated with mortality, acute kidney injury, PICU length-of-stay, duration of mechanical ventilation and vasoactive support. TBI and polytrauma patients did not have increased risk of neither of these outcomes. Conclusions: Unlike other ICU cohorts, fluid overload does not appear to be associated with worse clinical outcomes in severe trauma patients.2022-05-162022-05-16T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://hdl.handle.net/10216/142120TID:203176502engAna Patrícia de Matos Coelhoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T13:47:52Zoai:repositorio-aberto.up.pt:10216/142120Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:47:52.117760Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Fluid Overload in Pediatric Severe Trauma |
title |
Fluid Overload in Pediatric Severe Trauma |
spellingShingle |
Fluid Overload in Pediatric Severe Trauma Ana Patrícia de Matos Coelho Medicina clínica Clinical medicine |
title_short |
Fluid Overload in Pediatric Severe Trauma |
title_full |
Fluid Overload in Pediatric Severe Trauma |
title_fullStr |
Fluid Overload in Pediatric Severe Trauma |
title_full_unstemmed |
Fluid Overload in Pediatric Severe Trauma |
title_sort |
Fluid Overload in Pediatric Severe Trauma |
author |
Ana Patrícia de Matos Coelho |
author_facet |
Ana Patrícia de Matos Coelho |
author_role |
author |
dc.contributor.author.fl_str_mv |
Ana Patrícia de Matos Coelho |
dc.subject.por.fl_str_mv |
Medicina clínica Clinical medicine |
topic |
Medicina clínica Clinical medicine |
description |
Background and objective: Trauma is a leading cause of pediatric mortality and potential years of life lost in the developed world. Critically ill children frequently achieve a net positive fluid balance and fluid overload is associated with substantial morbidity and mortality in pediatrics. This study investigated the association between fluid balance status and clinical outcomes in pediatric severe trauma patients. Methods: This is a unicentric, observational retrospective study. Sixty-six children with severe trauma admitted to a tertiary hospital PICU over a 3-year period were included. Electronic medical records were reviewed. Fluid balance in the first 24 hours of PICU admission was calculated. Results: Males comprised 56% of the sample and median age was 12.2 years. Forty-one (62,1%) suffered polytrauma, 32 of these with traumatic brain injury (TBI), and 25 had isolated TBI. Seventeen (25,7%) patients had early fluid overload (FO). Early FO was not significantly associated with mortality, acute kidney injury, PICU length-of-stay, duration of mechanical ventilation and vasoactive support. TBI and polytrauma patients did not have increased risk of neither of these outcomes. Conclusions: Unlike other ICU cohorts, fluid overload does not appear to be associated with worse clinical outcomes in severe trauma patients. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-05-16 2022-05-16T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/10216/142120 TID:203176502 |
url |
https://hdl.handle.net/10216/142120 |
identifier_str_mv |
TID:203176502 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799135796808122368 |