Evolution of outpatient antibiotic use in Portugal mainland 2000-2009
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1 |
Resumo: | Introduction: In the latest years, the increasing resistance to antibiotics has become a serious public health issue. The resistance to antimicrobial agents is multifactorial although several studies have shown that the large use of antibiotics for therapeutical and prophylactic purposes, and particularly their misuse, is one factor that contributes most to this problem. Aim: To assess the evolution of antibiotic consumption in Portugal, Health Regions and Districts of Portugal, from 2000 to 2009. Material and Methods: Descriptive observational study using as source of information a database of outpatient antibiotic prescription provided by Infarmed, National Authority of Medicines and Health Products. Antibiotic consumption is estimated up from medical prescription, and expressed in DDD/1000 inhabitants/day (DHD). Results: From 2000 to 2009 antibiotic total consumption varied between 24,12 DHD and 22,03 DHD, which means a decrease by 8,65%. The use of tetracyclines (J01A), cephalosporins (J01D), sulphonamides (J01E), quinolones (J01M) and other antibacterials (J01B, J01G and J01X) decreased during the aforesaid time period. By contrast, there was an increase in the use of the combination penicilin and beta-lactamases inhibitor, and macrolides (J01F). Between 2000 and 2009 there was a significant decrease in the use of outpatient cephalosporins ( - 43,50%). Most notable is the large reduction of the use of cephalosporins between 2000 and 2009 (-43.50%) and also the decrease in the consumption of quinolones (-15.31%). Conclusion: Although there has been a decrease in the use of antibiotics in Portugal, their consumption is still high. The current study provides information that may be useful to regional Health Authorities in order to develop educational activities, for the population or health professionals, which can promote the rational use of antibiotics. |
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Evolution of outpatient antibiotic use in Portugal mainland 2000-2009A evolução do consumo de antibióticos em ambulatório em Portugal continental 2000-2009Introduction: In the latest years, the increasing resistance to antibiotics has become a serious public health issue. The resistance to antimicrobial agents is multifactorial although several studies have shown that the large use of antibiotics for therapeutical and prophylactic purposes, and particularly their misuse, is one factor that contributes most to this problem. Aim: To assess the evolution of antibiotic consumption in Portugal, Health Regions and Districts of Portugal, from 2000 to 2009. Material and Methods: Descriptive observational study using as source of information a database of outpatient antibiotic prescription provided by Infarmed, National Authority of Medicines and Health Products. Antibiotic consumption is estimated up from medical prescription, and expressed in DDD/1000 inhabitants/day (DHD). Results: From 2000 to 2009 antibiotic total consumption varied between 24,12 DHD and 22,03 DHD, which means a decrease by 8,65%. The use of tetracyclines (J01A), cephalosporins (J01D), sulphonamides (J01E), quinolones (J01M) and other antibacterials (J01B, J01G and J01X) decreased during the aforesaid time period. By contrast, there was an increase in the use of the combination penicilin and beta-lactamases inhibitor, and macrolides (J01F). Between 2000 and 2009 there was a significant decrease in the use of outpatient cephalosporins ( - 43,50%). Most notable is the large reduction of the use of cephalosporins between 2000 and 2009 (-43.50%) and also the decrease in the consumption of quinolones (-15.31%). Conclusion: Although there has been a decrease in the use of antibiotics in Portugal, their consumption is still high. The current study provides information that may be useful to regional Health Authorities in order to develop educational activities, for the population or health professionals, which can promote the rational use of antibiotics.Introdução: Nos últimos anos o aumento da resistência a antibióticos tornou-se um importante problema de Saúde Pública. A origem da resistência a agentes antimicrobianos é multifactorial, contudo vários estudos têm evidenciado que o elevado consumo de antibióticos para fins terapêuticos e profilácticos, e particularmente o seu uso inadequado, é um dos factores que mais contribui para este problema. Objectivo: Caracterizar a evolução do consumo de antibióticos no País, Regiões de Saúde e Distritos do Continente Português, de 2000 a 2009. Material e métodos: Trata-se de um estudo observacional descritivo utilizando como fonte de informação uma base de dados de dispensa de antibióticos em ambulatório fornecida pelo INFARMED, Autoridade Nacional do Medicamento e Produtos de Saúde, I.P. O consumo de antibióticos é estimado a partir da prescrição médica e é expresso em DDD/1000 habitantes/dia (DHD). Resultados: O consumo total de antibióticos no período 2000-2009 variou entre 24,12 DHD e 22,03 DHD, o que corresponde a um decréscimo de 8,65%. O uso das tetraciclinas (J01A), cefalosporinas (J01D), sulfonamidas (J01E), quinolonas (J01M) e outros antibacterianos (J01B, J01G e J01X) diminuiu no período referido. Contrariamente, verificou-se um acréscimo no uso das penicilinas com associação de inibidor das beta-lactamases (J01CR), e dos macrólidos (J01F). Salienta-se a grande redução, do uso de cefalosporinas entre 2000 e 2009 (-43,50%) em ambulatório e também o decréscimo no consumo de quinolonas (-15,31%). Conclusões: Apesar de se ter verificado uma redução no uso dos antibióticos em Portugal, o país continua a apresentar um valor elevado no consumo destes medicamentos. Este estudo fornece informação que poderá ser útil às Administrações Regionais de Saúde para desenvolver actividades educativas, quer junto da população quer junto dos profissionais de saúde, no sentido de promover o uso racional dos antibióticos.Ordem dos Médicos2012-05-25info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/x-pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1oai:ojs.www.actamedicaportuguesa.com:article/1Acta Médica Portuguesa; Vol. 25 No. 1 (2012): January-February; 20-28Acta Médica Portuguesa; Vol. 25 N.º 1 (2012): Janeiro-Fevereiro; 20-281646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1/9Ramalhinho, IsabelRibeirinho, MafaldaVieira, IsauraCabrita, Joseinfo:eu-repo/semantics/openAccess2022-12-20T10:55:34Zoai:ojs.www.actamedicaportuguesa.com:article/1Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:17.686092Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Evolution of outpatient antibiotic use in Portugal mainland 2000-2009 A evolução do consumo de antibióticos em ambulatório em Portugal continental 2000-2009 |
title |
Evolution of outpatient antibiotic use in Portugal mainland 2000-2009 |
spellingShingle |
Evolution of outpatient antibiotic use in Portugal mainland 2000-2009 Ramalhinho, Isabel |
title_short |
Evolution of outpatient antibiotic use in Portugal mainland 2000-2009 |
title_full |
Evolution of outpatient antibiotic use in Portugal mainland 2000-2009 |
title_fullStr |
Evolution of outpatient antibiotic use in Portugal mainland 2000-2009 |
title_full_unstemmed |
Evolution of outpatient antibiotic use in Portugal mainland 2000-2009 |
title_sort |
Evolution of outpatient antibiotic use in Portugal mainland 2000-2009 |
author |
Ramalhinho, Isabel |
author_facet |
Ramalhinho, Isabel Ribeirinho, Mafalda Vieira, Isaura Cabrita, Jose |
author_role |
author |
author2 |
Ribeirinho, Mafalda Vieira, Isaura Cabrita, Jose |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Ramalhinho, Isabel Ribeirinho, Mafalda Vieira, Isaura Cabrita, Jose |
description |
Introduction: In the latest years, the increasing resistance to antibiotics has become a serious public health issue. The resistance to antimicrobial agents is multifactorial although several studies have shown that the large use of antibiotics for therapeutical and prophylactic purposes, and particularly their misuse, is one factor that contributes most to this problem. Aim: To assess the evolution of antibiotic consumption in Portugal, Health Regions and Districts of Portugal, from 2000 to 2009. Material and Methods: Descriptive observational study using as source of information a database of outpatient antibiotic prescription provided by Infarmed, National Authority of Medicines and Health Products. Antibiotic consumption is estimated up from medical prescription, and expressed in DDD/1000 inhabitants/day (DHD). Results: From 2000 to 2009 antibiotic total consumption varied between 24,12 DHD and 22,03 DHD, which means a decrease by 8,65%. The use of tetracyclines (J01A), cephalosporins (J01D), sulphonamides (J01E), quinolones (J01M) and other antibacterials (J01B, J01G and J01X) decreased during the aforesaid time period. By contrast, there was an increase in the use of the combination penicilin and beta-lactamases inhibitor, and macrolides (J01F). Between 2000 and 2009 there was a significant decrease in the use of outpatient cephalosporins ( - 43,50%). Most notable is the large reduction of the use of cephalosporins between 2000 and 2009 (-43.50%) and also the decrease in the consumption of quinolones (-15.31%). Conclusion: Although there has been a decrease in the use of antibiotics in Portugal, their consumption is still high. The current study provides information that may be useful to regional Health Authorities in order to develop educational activities, for the population or health professionals, which can promote the rational use of antibiotics. |
publishDate |
2012 |
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2012-05-25 |
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info:eu-repo/semantics/publishedVersion |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1 oai:ojs.www.actamedicaportuguesa.com:article/1 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1/9 |
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Ordem dos Médicos |
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Ordem dos Médicos |
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Acta Médica Portuguesa; Vol. 25 No. 1 (2012): January-February; 20-28 Acta Médica Portuguesa; Vol. 25 N.º 1 (2012): Janeiro-Fevereiro; 20-28 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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