Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies

Detalhes bibliográficos
Autor(a) principal: Traylor, M.
Data de Publicação: 2012
Outros Autores: Farrall, M., Holliday, E.G., Sudlow, C., Hopewell, J.C., Cheng, Y.C., Fornage, M., Ikram, M.A., Malik, R., Bevan, S., Thorsteinsdottir, U., Nalls, M.A., Longstreth, W., Wiggins, K.L., Yadav, S., Parati, E.A., Destefano, A.L., Worrall, B.B., Kittner, S.J., Khan, M.S., Reiner, A.P., Helgadottir, A., Achterberg, S., Fernandez-Cadenas, I., Abboud, S., Schmidt, R., Walters, M., Chen, W.M., Ringelstein, E.B., O'Donnell, M., Ho, W.K., Pera, J., Lemmens, R., Norrving, B., Higgins, P., Benn, M., Sale, M., Kuhlenbäumer, G., Doney, A.S., Vicente, A.M., Delavaran, H., Algra, A., Davies, G., Oliveira, S.A., Palmer, C.N., Deary, I., Schmidt, H., Pandolfo, M., Montaner, J., Carty, C., de Bakker, P.I., Kostulas, K., Ferro, J.M., van Zuydam, N.R, Valdimarsson, E., Nordestgaard, B.G., Lindgren, A., Thijs, V., Slowik, A., Saleheen, D., Paré, G., Berger, K., Thorleifsson, G., Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2), Hofman, A., Mosley, T.H., Mitchell, B.D., Furie, K., Clarke, R., Levi, C., Seshadri, S., Gschwendtner, A., Boncoraglio, G.B., Sharma, P., Bis, J.C., Gretarsdottir, S., Psaty, B.M., Rothwell, P.M., Rosand, J., Meschia, J.F., Stefansson, K., Dichgans, M., Markus, H.S., International Stroke Genetics Consortium.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/1472
Resumo: Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE collaboration with the aim of validating associations from previous GWAS and identifying novel genetic associations through meta-analysis of GWAS datasets for ischaemic stroke and its subtypes.
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spelling Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studiesDoenças Cardio e Cérebro-vascularesVarious genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE collaboration with the aim of validating associations from previous GWAS and identifying novel genetic associations through meta-analysis of GWAS datasets for ischaemic stroke and its subtypes.ElsevierRepositório Científico do Instituto Nacional de SaúdeTraylor, M.Farrall, M.Holliday, E.G.Sudlow, C.Hopewell, J.C.Cheng, Y.C.Fornage, M.Ikram, M.A.Malik, R.Bevan, S.Thorsteinsdottir, U.Nalls, M.A.Longstreth, W.Wiggins, K.L.Yadav, S.Parati, E.A.Destefano, A.L.Worrall, B.B.Kittner, S.J.Khan, M.S.Reiner, A.P.Helgadottir, A.Achterberg, S.Fernandez-Cadenas, I.Abboud, S.Schmidt, R.Walters, M.Chen, W.M.Ringelstein, E.B.O'Donnell, M.Ho, W.K.Pera, J.Lemmens, R.Norrving, B.Higgins, P.Benn, M.Sale, M.Kuhlenbäumer, G.Doney, A.S.Vicente, A.M.Delavaran, H.Algra, A.Davies, G.Oliveira, S.A.Palmer, C.N.Deary, I.Schmidt, H.Pandolfo, M.Montaner, J.Carty, C.de Bakker, P.I.Kostulas, K.Ferro, J.M.van Zuydam, N.R,Valdimarsson, E.Nordestgaard, B.G.Lindgren, A.Thijs, V.Slowik, A.Saleheen, D.Paré, G.Berger, K.Thorleifsson, G.Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2)Hofman, A.Mosley, T.H.Mitchell, B.D.Furie, K.Clarke, R.Levi, C.Seshadri, S.Gschwendtner, A.Boncoraglio, G.B.Sharma, P.Bis, J.C.Gretarsdottir, S.Psaty, B.M.Rothwell, P.M.Rosand, J.Meschia, J.F.Stefansson, K.Dichgans, M.Markus, H.S.International Stroke Genetics Consortium.2013-02-25T16:35:10Z2012-10-052012-10-05T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/1472engLancet Neurol. 2012 Nov;11(11):951-62. doi: 10.1016/S1474-4422(12)70234-X. Epub 2012 Oct 51474-4422doi: 10.1016/S1474-4422(12)70234-Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:38:45Zoai:repositorio.insa.pt:10400.18/1472Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:36:36.059791Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies
title Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies
spellingShingle Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies
Traylor, M.
Doenças Cardio e Cérebro-vasculares
title_short Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies
title_full Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies
title_fullStr Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies
title_full_unstemmed Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies
title_sort Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies
author Traylor, M.
author_facet Traylor, M.
Farrall, M.
Holliday, E.G.
Sudlow, C.
Hopewell, J.C.
Cheng, Y.C.
Fornage, M.
Ikram, M.A.
Malik, R.
Bevan, S.
Thorsteinsdottir, U.
Nalls, M.A.
Longstreth, W.
Wiggins, K.L.
Yadav, S.
Parati, E.A.
Destefano, A.L.
Worrall, B.B.
Kittner, S.J.
Khan, M.S.
Reiner, A.P.
Helgadottir, A.
Achterberg, S.
Fernandez-Cadenas, I.
Abboud, S.
Schmidt, R.
Walters, M.
Chen, W.M.
Ringelstein, E.B.
O'Donnell, M.
Ho, W.K.
Pera, J.
Lemmens, R.
Norrving, B.
Higgins, P.
Benn, M.
Sale, M.
Kuhlenbäumer, G.
Doney, A.S.
Vicente, A.M.
Delavaran, H.
Algra, A.
Davies, G.
Oliveira, S.A.
Palmer, C.N.
Deary, I.
Schmidt, H.
Pandolfo, M.
Montaner, J.
Carty, C.
de Bakker, P.I.
Kostulas, K.
Ferro, J.M.
van Zuydam, N.R,
Valdimarsson, E.
Nordestgaard, B.G.
Lindgren, A.
Thijs, V.
Slowik, A.
Saleheen, D.
Paré, G.
Berger, K.
Thorleifsson, G.
Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2)
Hofman, A.
Mosley, T.H.
Mitchell, B.D.
Furie, K.
Clarke, R.
Levi, C.
Seshadri, S.
Gschwendtner, A.
Boncoraglio, G.B.
Sharma, P.
Bis, J.C.
Gretarsdottir, S.
Psaty, B.M.
Rothwell, P.M.
Rosand, J.
Meschia, J.F.
Stefansson, K.
Dichgans, M.
Markus, H.S.
International Stroke Genetics Consortium.
author_role author
author2 Farrall, M.
Holliday, E.G.
Sudlow, C.
Hopewell, J.C.
Cheng, Y.C.
Fornage, M.
Ikram, M.A.
Malik, R.
Bevan, S.
Thorsteinsdottir, U.
Nalls, M.A.
Longstreth, W.
Wiggins, K.L.
Yadav, S.
Parati, E.A.
Destefano, A.L.
Worrall, B.B.
Kittner, S.J.
Khan, M.S.
Reiner, A.P.
Helgadottir, A.
Achterberg, S.
Fernandez-Cadenas, I.
Abboud, S.
Schmidt, R.
Walters, M.
Chen, W.M.
Ringelstein, E.B.
O'Donnell, M.
Ho, W.K.
Pera, J.
Lemmens, R.
Norrving, B.
Higgins, P.
Benn, M.
Sale, M.
Kuhlenbäumer, G.
Doney, A.S.
Vicente, A.M.
Delavaran, H.
Algra, A.
Davies, G.
Oliveira, S.A.
Palmer, C.N.
Deary, I.
Schmidt, H.
Pandolfo, M.
Montaner, J.
Carty, C.
de Bakker, P.I.
Kostulas, K.
Ferro, J.M.
van Zuydam, N.R,
Valdimarsson, E.
Nordestgaard, B.G.
Lindgren, A.
Thijs, V.
Slowik, A.
Saleheen, D.
Paré, G.
Berger, K.
Thorleifsson, G.
Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2)
Hofman, A.
Mosley, T.H.
Mitchell, B.D.
Furie, K.
Clarke, R.
Levi, C.
Seshadri, S.
Gschwendtner, A.
Boncoraglio, G.B.
Sharma, P.
Bis, J.C.
Gretarsdottir, S.
Psaty, B.M.
Rothwell, P.M.
Rosand, J.
Meschia, J.F.
Stefansson, K.
Dichgans, M.
Markus, H.S.
International Stroke Genetics Consortium.
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dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Traylor, M.
Farrall, M.
Holliday, E.G.
Sudlow, C.
Hopewell, J.C.
Cheng, Y.C.
Fornage, M.
Ikram, M.A.
Malik, R.
Bevan, S.
Thorsteinsdottir, U.
Nalls, M.A.
Longstreth, W.
Wiggins, K.L.
Yadav, S.
Parati, E.A.
Destefano, A.L.
Worrall, B.B.
Kittner, S.J.
Khan, M.S.
Reiner, A.P.
Helgadottir, A.
Achterberg, S.
Fernandez-Cadenas, I.
Abboud, S.
Schmidt, R.
Walters, M.
Chen, W.M.
Ringelstein, E.B.
O'Donnell, M.
Ho, W.K.
Pera, J.
Lemmens, R.
Norrving, B.
Higgins, P.
Benn, M.
Sale, M.
Kuhlenbäumer, G.
Doney, A.S.
Vicente, A.M.
Delavaran, H.
Algra, A.
Davies, G.
Oliveira, S.A.
Palmer, C.N.
Deary, I.
Schmidt, H.
Pandolfo, M.
Montaner, J.
Carty, C.
de Bakker, P.I.
Kostulas, K.
Ferro, J.M.
van Zuydam, N.R,
Valdimarsson, E.
Nordestgaard, B.G.
Lindgren, A.
Thijs, V.
Slowik, A.
Saleheen, D.
Paré, G.
Berger, K.
Thorleifsson, G.
Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2)
Hofman, A.
Mosley, T.H.
Mitchell, B.D.
Furie, K.
Clarke, R.
Levi, C.
Seshadri, S.
Gschwendtner, A.
Boncoraglio, G.B.
Sharma, P.
Bis, J.C.
Gretarsdottir, S.
Psaty, B.M.
Rothwell, P.M.
Rosand, J.
Meschia, J.F.
Stefansson, K.
Dichgans, M.
Markus, H.S.
International Stroke Genetics Consortium.
dc.subject.por.fl_str_mv Doenças Cardio e Cérebro-vasculares
topic Doenças Cardio e Cérebro-vasculares
description Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE collaboration with the aim of validating associations from previous GWAS and identifying novel genetic associations through meta-analysis of GWAS datasets for ischaemic stroke and its subtypes.
publishDate 2012
dc.date.none.fl_str_mv 2012-10-05
2012-10-05T00:00:00Z
2013-02-25T16:35:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/1472
url http://hdl.handle.net/10400.18/1472
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Lancet Neurol. 2012 Nov;11(11):951-62. doi: 10.1016/S1474-4422(12)70234-X. Epub 2012 Oct 5
1474-4422
doi: 10.1016/S1474-4422(12)70234-X
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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