Reductionism at the vertebrate kinetochore
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.7/482 |
Resumo: | The kinetochore forms the site of attachment for mitotic spindle microtubules driving chromosome segregation. The interdependent protein interactions in this large structure have made it difficult to dissect the function of its components. In this issue, Hori et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201210106) present a novel and powerful methodology to address the sufficiency of individual proteins for the creation of a functional de novo centromere. |
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Reductionism at the vertebrate kinetochoreAutoantigensChromosomal Proteins, Non-HistoneDNA-Binding ProteinsKinetochoresMultiprotein ComplexesThe kinetochore forms the site of attachment for mitotic spindle microtubules driving chromosome segregation. The interdependent protein interactions in this large structure have made it difficult to dissect the function of its components. In this issue, Hori et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201210106) present a novel and powerful methodology to address the sufficiency of individual proteins for the creation of a functional de novo centromere.Não possuí patrocionadores.The Rockefeller University PressARCAStankovic, A.Jansen, L. E. T.2015-11-09T18:48:25Z2013-01-072013-01-07T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/482engReductionism at the vertebrate kinetochore Ana Stankovic and Lars E.T. Jansen J Cell Biol 2013 200:7-8. Published December 31, 2012, doi:10.1083/jcb.20121200510.1083/jcb.201212005info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:34:52Zoai:arca.igc.gulbenkian.pt:10400.7/482Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:45.510866Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Reductionism at the vertebrate kinetochore |
title |
Reductionism at the vertebrate kinetochore |
spellingShingle |
Reductionism at the vertebrate kinetochore Stankovic, A. Autoantigens Chromosomal Proteins, Non-Histone DNA-Binding Proteins Kinetochores Multiprotein Complexes |
title_short |
Reductionism at the vertebrate kinetochore |
title_full |
Reductionism at the vertebrate kinetochore |
title_fullStr |
Reductionism at the vertebrate kinetochore |
title_full_unstemmed |
Reductionism at the vertebrate kinetochore |
title_sort |
Reductionism at the vertebrate kinetochore |
author |
Stankovic, A. |
author_facet |
Stankovic, A. Jansen, L. E. T. |
author_role |
author |
author2 |
Jansen, L. E. T. |
author2_role |
author |
dc.contributor.none.fl_str_mv |
ARCA |
dc.contributor.author.fl_str_mv |
Stankovic, A. Jansen, L. E. T. |
dc.subject.por.fl_str_mv |
Autoantigens Chromosomal Proteins, Non-Histone DNA-Binding Proteins Kinetochores Multiprotein Complexes |
topic |
Autoantigens Chromosomal Proteins, Non-Histone DNA-Binding Proteins Kinetochores Multiprotein Complexes |
description |
The kinetochore forms the site of attachment for mitotic spindle microtubules driving chromosome segregation. The interdependent protein interactions in this large structure have made it difficult to dissect the function of its components. In this issue, Hori et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201210106) present a novel and powerful methodology to address the sufficiency of individual proteins for the creation of a functional de novo centromere. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-01-07 2013-01-07T00:00:00Z 2015-11-09T18:48:25Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.7/482 |
url |
http://hdl.handle.net/10400.7/482 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Reductionism at the vertebrate kinetochore Ana Stankovic and Lars E.T. Jansen J Cell Biol 2013 200:7-8. Published December 31, 2012, doi:10.1083/jcb.201212005 10.1083/jcb.201212005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
The Rockefeller University Press |
publisher.none.fl_str_mv |
The Rockefeller University Press |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799130572970262528 |