Nephrocalcinosis and Subcutaneous Fat Necrosis

Detalhes bibliográficos
Autor(a) principal: Gomes, Cláudia
Data de Publicação: 2014
Outros Autores: Lobo, Luísa, Azevedo, António Siborro, Simão, Carla
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5192
Resumo: Subcutaneous fat necrosis of the newborn is an uncommon, transient and self-healing panniculits. This entity generally follows an uncomplicated course, however there are rare and important complications. The authors present a case of a newborn with subcutaneous fat necrosis complicated by hypercalcemia and nephrocalcinosis. The pathogenesis of hypercalcemia is not fully understood and the nephrocalcinosis can evolve to chronic kidney disease. Clinicians should be aware of subcutaneous fat necrosis as a possible riskfactor for hypercalcemia and patients should have serial serum and urinary calcium determinations for up to 6 months after the appearance of the skin lesions. The early diagnosis and prompt treatment of hypercalcemia are essential to prevent severe complications.Keywords: Hypercalcemia; Fat Necrosis; Infant, Newborn; Nephrocalcinosis; Subcutaneous Fat. 
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spelling Nephrocalcinosis and Subcutaneous Fat NecrosisNefrocalcinose e Necrose Gorda do Tecido Celular SubcutâneoSubcutaneous fat necrosis of the newborn is an uncommon, transient and self-healing panniculits. This entity generally follows an uncomplicated course, however there are rare and important complications. The authors present a case of a newborn with subcutaneous fat necrosis complicated by hypercalcemia and nephrocalcinosis. The pathogenesis of hypercalcemia is not fully understood and the nephrocalcinosis can evolve to chronic kidney disease. Clinicians should be aware of subcutaneous fat necrosis as a possible riskfactor for hypercalcemia and patients should have serial serum and urinary calcium determinations for up to 6 months after the appearance of the skin lesions. The early diagnosis and prompt treatment of hypercalcemia are essential to prevent severe complications.Keywords: Hypercalcemia; Fat Necrosis; Infant, Newborn; Nephrocalcinosis; Subcutaneous Fat. A necrose gorda do tecido celular subcutâneo do recém-nascido é uma paniculite rara, transitória e auto-limitada. Tipicamente apresenta evolução favorável, contudo podem surgir complicações potencialmente graves. Apresenta-se um caso que evoluiu com hipercalcémia e nefrocalcinose. A etiopatogenia da hipercalcémia é ainda pouco compreendida e a nefrocalcinose pode constituir uma causa de doença renal crónica. A monitorização regular dos valores de cálcio sérico e urinário neste contexto é essencial, no mínimo até 6 meses após a resolução das lesões cutâneas, porque o diagnóstico precoce e a terapêutica adequada constituem a única possibilidade de prevenir complicações mais graves.Palavras-chave: Hipercalcémia; Necrose Gorda Subcutânea; Nefrocalcinose; Recém-Nascido.Ordem dos Médicos2014-12-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfimage/jpegimage/jpegimage/jpegimage/jpeghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5192oai:ojs.www.actamedicaportuguesa.com:article/5192Acta Médica Portuguesa; Vol. 28 No. 1 (2015): January-February; 119-122Acta Médica Portuguesa; Vol. 28 N.º 1 (2015): Janeiro-Fevereiro; 119-1221646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5192https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5192/4220https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5192/7476https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5192/7477https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5192/7478https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5192/7544Gomes, CláudiaLobo, LuísaAzevedo, António SiborroSimão, Carlainfo:eu-repo/semantics/openAccess2022-12-20T11:04:14Zoai:ojs.www.actamedicaportuguesa.com:article/5192Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:02.725158Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Nephrocalcinosis and Subcutaneous Fat Necrosis
Nefrocalcinose e Necrose Gorda do Tecido Celular Subcutâneo
title Nephrocalcinosis and Subcutaneous Fat Necrosis
spellingShingle Nephrocalcinosis and Subcutaneous Fat Necrosis
Gomes, Cláudia
title_short Nephrocalcinosis and Subcutaneous Fat Necrosis
title_full Nephrocalcinosis and Subcutaneous Fat Necrosis
title_fullStr Nephrocalcinosis and Subcutaneous Fat Necrosis
title_full_unstemmed Nephrocalcinosis and Subcutaneous Fat Necrosis
title_sort Nephrocalcinosis and Subcutaneous Fat Necrosis
author Gomes, Cláudia
author_facet Gomes, Cláudia
Lobo, Luísa
Azevedo, António Siborro
Simão, Carla
author_role author
author2 Lobo, Luísa
Azevedo, António Siborro
Simão, Carla
author2_role author
author
author
dc.contributor.author.fl_str_mv Gomes, Cláudia
Lobo, Luísa
Azevedo, António Siborro
Simão, Carla
description Subcutaneous fat necrosis of the newborn is an uncommon, transient and self-healing panniculits. This entity generally follows an uncomplicated course, however there are rare and important complications. The authors present a case of a newborn with subcutaneous fat necrosis complicated by hypercalcemia and nephrocalcinosis. The pathogenesis of hypercalcemia is not fully understood and the nephrocalcinosis can evolve to chronic kidney disease. Clinicians should be aware of subcutaneous fat necrosis as a possible riskfactor for hypercalcemia and patients should have serial serum and urinary calcium determinations for up to 6 months after the appearance of the skin lesions. The early diagnosis and prompt treatment of hypercalcemia are essential to prevent severe complications.Keywords: Hypercalcemia; Fat Necrosis; Infant, Newborn; Nephrocalcinosis; Subcutaneous Fat. 
publishDate 2014
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 28 No. 1 (2015): January-February; 119-122
Acta Médica Portuguesa; Vol. 28 N.º 1 (2015): Janeiro-Fevereiro; 119-122
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