The tetranuclear copper active site of nitrous oxide reductase: the CuZ center

Detalhes bibliográficos
Autor(a) principal: Dell’Acqua, Simone
Data de Publicação: 2011
Outros Autores: Pauleta, Sofia R., Moura, Isabel, Moura, José J. G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/8620
Resumo: J Biol Inorg Chem (2011) 16:183–194 DOI 10.1007/s00775-011-0753-3
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spelling The tetranuclear copper active site of nitrous oxide reductase: the CuZ centerCopper proteinsCuZ centerNitrous oxide reductaseDenitrificationJ Biol Inorg Chem (2011) 16:183–194 DOI 10.1007/s00775-011-0753-3This review focuses on the novel CuZ center of nitrous oxide reductase, an important enzyme owing to the environmental significance of the reaction it catalyzes, reduction of nitrous oxide, and the unusual nature of its catalytic center, named CuZ. The structure of the CuZ center, the unique tetranuclear copper center found in this enzyme, opened a novel area of research in metallobiochemistry. In the last decade, there has been progress in defining the structure of the CuZ center, characterizing the mechanism of nitrous oxide reduction, and identifying intermediates of this reaction. In addition, the determination of the structure of the CuZ center allowed a structural interpretation of the spectroscopic data, which was supported by theoretical calculations. The current knowledge of the structure, function, and spectroscopic characterization of the CuZ center is described here. We would like to stress that although many questions have been answered, the CuZ center remains a scientific challenge, with many hypotheses still being formed.SpringerRUNDell’Acqua, SimonePauleta, Sofia R.Moura, IsabelMoura, José J. G.2013-01-30T11:52:05Z20112011-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/8620eng1432-1327info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T03:41:26Zoai:run.unl.pt:10362/8620Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:18:19.505876Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The tetranuclear copper active site of nitrous oxide reductase: the CuZ center
title The tetranuclear copper active site of nitrous oxide reductase: the CuZ center
spellingShingle The tetranuclear copper active site of nitrous oxide reductase: the CuZ center
Dell’Acqua, Simone
Copper proteins
CuZ center
Nitrous oxide reductase
Denitrification
title_short The tetranuclear copper active site of nitrous oxide reductase: the CuZ center
title_full The tetranuclear copper active site of nitrous oxide reductase: the CuZ center
title_fullStr The tetranuclear copper active site of nitrous oxide reductase: the CuZ center
title_full_unstemmed The tetranuclear copper active site of nitrous oxide reductase: the CuZ center
title_sort The tetranuclear copper active site of nitrous oxide reductase: the CuZ center
author Dell’Acqua, Simone
author_facet Dell’Acqua, Simone
Pauleta, Sofia R.
Moura, Isabel
Moura, José J. G.
author_role author
author2 Pauleta, Sofia R.
Moura, Isabel
Moura, José J. G.
author2_role author
author
author
dc.contributor.none.fl_str_mv RUN
dc.contributor.author.fl_str_mv Dell’Acqua, Simone
Pauleta, Sofia R.
Moura, Isabel
Moura, José J. G.
dc.subject.por.fl_str_mv Copper proteins
CuZ center
Nitrous oxide reductase
Denitrification
topic Copper proteins
CuZ center
Nitrous oxide reductase
Denitrification
description J Biol Inorg Chem (2011) 16:183–194 DOI 10.1007/s00775-011-0753-3
publishDate 2011
dc.date.none.fl_str_mv 2011
2011-01-01T00:00:00Z
2013-01-30T11:52:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/8620
url http://hdl.handle.net/10362/8620
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1432-1327
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
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