ANALYTICAL MARKERS THAT INFLUENCE THE RESULTS OF REVASCULARIZATION SURGERY IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE

• Autor(a) principal: Sousa, Pedro Pinto
• Data de Publicação: 2021
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://doi.org/10.48750/acv.288
• topic: Peripheral arterial disease; Analytical markers; Vascular surgery; Revascularization; Doença arterial periférica; Marcadores analíticos; Cirurgia vascular; Revascularização

Introduction: Patients with peripheral arterial occlusive disease and critical limb ischemia require limb revascularization to avoid limb loss. Nevertheless, they frequently present analytical disorders that interfere with outcomes. Methods: A retrospective study was conducted evolving every consecutive patient admitted and elective submitted to limb revascularization at a single institution between 2012 and 2014. Preoperative analytical data was collected and statistical analysis was conducted to determine any eventual correlation. Primary outcomes were Bypass patency, limb loss and mortality. Results: 174 patients were analyzed, 158 (91%) males, with a mean age of 67 ± 9 years. Concerning patency, above-knee bypass had better patency at 6 and 12 months (86% vs 75% e 82% vs 60%) compared to below-knee. Also, male patients had better results compared to female (90% vs 74% e 88% vs 62%). Regarding mortality and amputation rate, the condition was higher, with a statistical significance difference in the groups with renal failure (17% e 27% vs 5% e 7%, p=0.004); hypoalbuminemia and hypoproteinemia (19% e 29% vs 4% e 6%, p=0.03); elevated c-reactive protein (17% e 31% vs 6% e 7%, p=0.02) and Leriche Fontaine Grade IV (14% e 25% vs 5% e 4%). Conclusion: There are some specific analytical parameters that, when modified, imply worse prognostic for peripheral arterial disease patients and following that, should be, whenever possible promptly corrected.