Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe

Detalhes bibliográficos
Autor(a) principal: Kissling, Esther
Data de Publicação: 2022
Outros Autores: Hooiveld, Mariette, Martinez-Baz, Ivan, Mazagatos, Clara, William, Naoma, Vilcu, Ana Maria, Kooijman, Marjolein N., Ilic, Maja, Domegan, Lisa, Machado, Ausenda, De Lusignan, Simon, Lazar, Mihaela, Meijer, Adam, Brytting, Mia, Casado, Itziar, Larrauri, Amparo, Murray, Josephine L.K., Behillil, Sylvie, De Gier, Brechje, Mlinaric, Ivan, O'Donnell, Joan, Rodrigues, Ana Paula, Tsang, Ruby, Timnea, Olivia, De Lange, Marit, Riess, Maximilian, Castilla, Jesus, Pozo, Francisco, Hamilton, Mark, Falchi, Alessandra, Knol, Mirjam J., Filipovic, Sanja Kurecic, Dunford, Linda, Guiomar, Raquel, Cogdale, Jade, Cherciu, Carmen, Jansen, Tessa, Enkirch, Theresa, Basile, Luca, Connell, Jeff, Gomez, Veronica, Martin, Virginia Sandonis, Bacci, Sabrina, Rose, Angela M.C., Celentano, Lucia Pastore, Valenciano, Marta, Kislaya, Irina, Nunes, Baltazar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/149492
Resumo: Funding Information: This project received funding from the European Centre for Disease Prevention and Control (ECDC) under the contract ECD.11486. Funding Information: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101003673. Publisher Copyright: © 2022 European Centre for Disease Prevention and Control (ECDC). All rights reserved.
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spelling Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europemulticentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021EpidemiologyPublic Health, Environmental and Occupational HealthVirologySDG 3 - Good Health and Well-beingFunding Information: This project received funding from the European Centre for Disease Prevention and Control (ECDC) under the contract ECD.11486. Funding Information: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101003673. Publisher Copyright: © 2022 European Centre for Disease Prevention and Control (ECDC). All rights reserved.Introduction: In July and August 2021, the SARS-CoV-2 Delta variant dominated in Europe. Aim: Using a multicentre test-negative study, we measured COVID-19 vaccine effectiveness (VE) against symptomatic infection. Methods: Individuals with COVID-19 or acute respiratory symptoms at primary care/community level in 10 European countries were tested for SARS-CoV-2. We measured complete primary course overall VE by vaccine brand and by time since vaccination. Results: Overall VE was 74% (95% CI: 69-79), 76% (95% CI: 71-80), 63% (95% CI: 48-75) and 63% (95% CI: 16-83) among those aged 30-44, 45-59, 60-74 and ≥ 75 years, respectively. VE among those aged 30-59 years was 78% (95% CI: 75-81), 66% (95% CI: 58-73), 91% (95% CI: 87-94) and 52% (95% CI: 40-61), for Comirnaty, Vaxzevria, Spikevax and COVID-19 Vaccine Janssen, respectively. VE among people 60 years and older was 67% (95% CI: 52-77), 65% (95% CI: 48-76) and 83% (95% CI: 64-92) for Comirnaty, Vaxzevria and Spikevax, respectively. Comirnaty VE among those aged 30-59 years was 87% (95% CI: 83-89) at 14-29 days and 65% (95% CI: 56-71%) at ≥ 90 days between vaccination and onset of symptoms. Conclusions: VE against symptomatic infection with the SARS-CoV-2 Delta variant varied among brands, ranging from 52% to 91%. While some waning of the vaccine effect may be present (sample size limited this analysis to only Comirnaty), protection was 65% at 90 days or more between vaccination and onset.Escola Nacional de Saúde Pública (ENSP)RUNKissling, EstherHooiveld, MarietteMartinez-Baz, IvanMazagatos, ClaraWilliam, NaomaVilcu, Ana MariaKooijman, Marjolein N.Ilic, MajaDomegan, LisaMachado, AusendaDe Lusignan, SimonLazar, MihaelaMeijer, AdamBrytting, MiaCasado, ItziarLarrauri, AmparoMurray, Josephine L.K.Behillil, SylvieDe Gier, BrechjeMlinaric, IvanO'Donnell, JoanRodrigues, Ana PaulaTsang, RubyTimnea, OliviaDe Lange, MaritRiess, MaximilianCastilla, JesusPozo, FranciscoHamilton, MarkFalchi, AlessandraKnol, Mirjam J.Filipovic, Sanja KurecicDunford, LindaGuiomar, RaquelCogdale, JadeCherciu, CarmenJansen, TessaEnkirch, TheresaBasile, LucaConnell, JeffGomez, VeronicaMartin, Virginia SandonisBacci, SabrinaRose, Angela M.C.Celentano, Lucia PastoreValenciano, MartaKislaya, IrinaNunes, Baltazar2023-02-20T22:20:29Z2022-05-262022-05-26T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/149492eng1025-496XPURE: 53859097https://doi.org/10.2807/1560-7917.ES.2022.27.21.2101104info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:31:23Zoai:run.unl.pt:10362/149492Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:53:45.890502Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe
multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021
title Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe
spellingShingle Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe
Kissling, Esther
Epidemiology
Public Health, Environmental and Occupational Health
Virology
SDG 3 - Good Health and Well-being
title_short Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe
title_full Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe
title_fullStr Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe
title_full_unstemmed Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe
title_sort Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe
author Kissling, Esther
author_facet Kissling, Esther
Hooiveld, Mariette
Martinez-Baz, Ivan
Mazagatos, Clara
William, Naoma
Vilcu, Ana Maria
Kooijman, Marjolein N.
Ilic, Maja
Domegan, Lisa
Machado, Ausenda
De Lusignan, Simon
Lazar, Mihaela
Meijer, Adam
Brytting, Mia
Casado, Itziar
Larrauri, Amparo
Murray, Josephine L.K.
Behillil, Sylvie
De Gier, Brechje
Mlinaric, Ivan
O'Donnell, Joan
Rodrigues, Ana Paula
Tsang, Ruby
Timnea, Olivia
De Lange, Marit
Riess, Maximilian
Castilla, Jesus
Pozo, Francisco
Hamilton, Mark
Falchi, Alessandra
Knol, Mirjam J.
Filipovic, Sanja Kurecic
Dunford, Linda
Guiomar, Raquel
Cogdale, Jade
Cherciu, Carmen
Jansen, Tessa
Enkirch, Theresa
Basile, Luca
Connell, Jeff
Gomez, Veronica
Martin, Virginia Sandonis
Bacci, Sabrina
Rose, Angela M.C.
Celentano, Lucia Pastore
Valenciano, Marta
Kislaya, Irina
Nunes, Baltazar
author_role author
author2 Hooiveld, Mariette
Martinez-Baz, Ivan
Mazagatos, Clara
William, Naoma
Vilcu, Ana Maria
Kooijman, Marjolein N.
Ilic, Maja
Domegan, Lisa
Machado, Ausenda
De Lusignan, Simon
Lazar, Mihaela
Meijer, Adam
Brytting, Mia
Casado, Itziar
Larrauri, Amparo
Murray, Josephine L.K.
Behillil, Sylvie
De Gier, Brechje
Mlinaric, Ivan
O'Donnell, Joan
Rodrigues, Ana Paula
Tsang, Ruby
Timnea, Olivia
De Lange, Marit
Riess, Maximilian
Castilla, Jesus
Pozo, Francisco
Hamilton, Mark
Falchi, Alessandra
Knol, Mirjam J.
Filipovic, Sanja Kurecic
Dunford, Linda
Guiomar, Raquel
Cogdale, Jade
Cherciu, Carmen
Jansen, Tessa
Enkirch, Theresa
Basile, Luca
Connell, Jeff
Gomez, Veronica
Martin, Virginia Sandonis
Bacci, Sabrina
Rose, Angela M.C.
Celentano, Lucia Pastore
Valenciano, Marta
Kislaya, Irina
Nunes, Baltazar
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dc.contributor.none.fl_str_mv Escola Nacional de Saúde Pública (ENSP)
RUN
dc.contributor.author.fl_str_mv Kissling, Esther
Hooiveld, Mariette
Martinez-Baz, Ivan
Mazagatos, Clara
William, Naoma
Vilcu, Ana Maria
Kooijman, Marjolein N.
Ilic, Maja
Domegan, Lisa
Machado, Ausenda
De Lusignan, Simon
Lazar, Mihaela
Meijer, Adam
Brytting, Mia
Casado, Itziar
Larrauri, Amparo
Murray, Josephine L.K.
Behillil, Sylvie
De Gier, Brechje
Mlinaric, Ivan
O'Donnell, Joan
Rodrigues, Ana Paula
Tsang, Ruby
Timnea, Olivia
De Lange, Marit
Riess, Maximilian
Castilla, Jesus
Pozo, Francisco
Hamilton, Mark
Falchi, Alessandra
Knol, Mirjam J.
Filipovic, Sanja Kurecic
Dunford, Linda
Guiomar, Raquel
Cogdale, Jade
Cherciu, Carmen
Jansen, Tessa
Enkirch, Theresa
Basile, Luca
Connell, Jeff
Gomez, Veronica
Martin, Virginia Sandonis
Bacci, Sabrina
Rose, Angela M.C.
Celentano, Lucia Pastore
Valenciano, Marta
Kislaya, Irina
Nunes, Baltazar
dc.subject.por.fl_str_mv Epidemiology
Public Health, Environmental and Occupational Health
Virology
SDG 3 - Good Health and Well-being
topic Epidemiology
Public Health, Environmental and Occupational Health
Virology
SDG 3 - Good Health and Well-being
description Funding Information: This project received funding from the European Centre for Disease Prevention and Control (ECDC) under the contract ECD.11486. Funding Information: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101003673. Publisher Copyright: © 2022 European Centre for Disease Prevention and Control (ECDC). All rights reserved.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-26
2022-05-26T00:00:00Z
2023-02-20T22:20:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/149492
url http://hdl.handle.net/10362/149492
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1025-496X
PURE: 53859097
https://doi.org/10.2807/1560-7917.ES.2022.27.21.2101104
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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