Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/149492 |
Resumo: | Funding Information: This project received funding from the European Centre for Disease Prevention and Control (ECDC) under the contract ECD.11486. Funding Information: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101003673. Publisher Copyright: © 2022 European Centre for Disease Prevention and Control (ECDC). All rights reserved. |
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Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europemulticentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021EpidemiologyPublic Health, Environmental and Occupational HealthVirologySDG 3 - Good Health and Well-beingFunding Information: This project received funding from the European Centre for Disease Prevention and Control (ECDC) under the contract ECD.11486. Funding Information: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101003673. Publisher Copyright: © 2022 European Centre for Disease Prevention and Control (ECDC). All rights reserved.Introduction: In July and August 2021, the SARS-CoV-2 Delta variant dominated in Europe. Aim: Using a multicentre test-negative study, we measured COVID-19 vaccine effectiveness (VE) against symptomatic infection. Methods: Individuals with COVID-19 or acute respiratory symptoms at primary care/community level in 10 European countries were tested for SARS-CoV-2. We measured complete primary course overall VE by vaccine brand and by time since vaccination. Results: Overall VE was 74% (95% CI: 69-79), 76% (95% CI: 71-80), 63% (95% CI: 48-75) and 63% (95% CI: 16-83) among those aged 30-44, 45-59, 60-74 and ≥ 75 years, respectively. VE among those aged 30-59 years was 78% (95% CI: 75-81), 66% (95% CI: 58-73), 91% (95% CI: 87-94) and 52% (95% CI: 40-61), for Comirnaty, Vaxzevria, Spikevax and COVID-19 Vaccine Janssen, respectively. VE among people 60 years and older was 67% (95% CI: 52-77), 65% (95% CI: 48-76) and 83% (95% CI: 64-92) for Comirnaty, Vaxzevria and Spikevax, respectively. Comirnaty VE among those aged 30-59 years was 87% (95% CI: 83-89) at 14-29 days and 65% (95% CI: 56-71%) at ≥ 90 days between vaccination and onset of symptoms. Conclusions: VE against symptomatic infection with the SARS-CoV-2 Delta variant varied among brands, ranging from 52% to 91%. While some waning of the vaccine effect may be present (sample size limited this analysis to only Comirnaty), protection was 65% at 90 days or more between vaccination and onset.Escola Nacional de Saúde Pública (ENSP)RUNKissling, EstherHooiveld, MarietteMartinez-Baz, IvanMazagatos, ClaraWilliam, NaomaVilcu, Ana MariaKooijman, Marjolein N.Ilic, MajaDomegan, LisaMachado, AusendaDe Lusignan, SimonLazar, MihaelaMeijer, AdamBrytting, MiaCasado, ItziarLarrauri, AmparoMurray, Josephine L.K.Behillil, SylvieDe Gier, BrechjeMlinaric, IvanO'Donnell, JoanRodrigues, Ana PaulaTsang, RubyTimnea, OliviaDe Lange, MaritRiess, MaximilianCastilla, JesusPozo, FranciscoHamilton, MarkFalchi, AlessandraKnol, Mirjam J.Filipovic, Sanja KurecicDunford, LindaGuiomar, RaquelCogdale, JadeCherciu, CarmenJansen, TessaEnkirch, TheresaBasile, LucaConnell, JeffGomez, VeronicaMartin, Virginia SandonisBacci, SabrinaRose, Angela M.C.Celentano, Lucia PastoreValenciano, MartaKislaya, IrinaNunes, Baltazar2023-02-20T22:20:29Z2022-05-262022-05-26T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/149492eng1025-496XPURE: 53859097https://doi.org/10.2807/1560-7917.ES.2022.27.21.2101104info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:31:23Zoai:run.unl.pt:10362/149492Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:53:45.890502Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021 |
title |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe |
spellingShingle |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe Kissling, Esther Epidemiology Public Health, Environmental and Occupational Health Virology SDG 3 - Good Health and Well-being |
title_short |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe |
title_full |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe |
title_fullStr |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe |
title_full_unstemmed |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe |
title_sort |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe |
author |
Kissling, Esther |
author_facet |
Kissling, Esther Hooiveld, Mariette Martinez-Baz, Ivan Mazagatos, Clara William, Naoma Vilcu, Ana Maria Kooijman, Marjolein N. Ilic, Maja Domegan, Lisa Machado, Ausenda De Lusignan, Simon Lazar, Mihaela Meijer, Adam Brytting, Mia Casado, Itziar Larrauri, Amparo Murray, Josephine L.K. Behillil, Sylvie De Gier, Brechje Mlinaric, Ivan O'Donnell, Joan Rodrigues, Ana Paula Tsang, Ruby Timnea, Olivia De Lange, Marit Riess, Maximilian Castilla, Jesus Pozo, Francisco Hamilton, Mark Falchi, Alessandra Knol, Mirjam J. Filipovic, Sanja Kurecic Dunford, Linda Guiomar, Raquel Cogdale, Jade Cherciu, Carmen Jansen, Tessa Enkirch, Theresa Basile, Luca Connell, Jeff Gomez, Veronica Martin, Virginia Sandonis Bacci, Sabrina Rose, Angela M.C. Celentano, Lucia Pastore Valenciano, Marta Kislaya, Irina Nunes, Baltazar |
author_role |
author |
author2 |
Hooiveld, Mariette Martinez-Baz, Ivan Mazagatos, Clara William, Naoma Vilcu, Ana Maria Kooijman, Marjolein N. Ilic, Maja Domegan, Lisa Machado, Ausenda De Lusignan, Simon Lazar, Mihaela Meijer, Adam Brytting, Mia Casado, Itziar Larrauri, Amparo Murray, Josephine L.K. Behillil, Sylvie De Gier, Brechje Mlinaric, Ivan O'Donnell, Joan Rodrigues, Ana Paula Tsang, Ruby Timnea, Olivia De Lange, Marit Riess, Maximilian Castilla, Jesus Pozo, Francisco Hamilton, Mark Falchi, Alessandra Knol, Mirjam J. Filipovic, Sanja Kurecic Dunford, Linda Guiomar, Raquel Cogdale, Jade Cherciu, Carmen Jansen, Tessa Enkirch, Theresa Basile, Luca Connell, Jeff Gomez, Veronica Martin, Virginia Sandonis Bacci, Sabrina Rose, Angela M.C. Celentano, Lucia Pastore Valenciano, Marta Kislaya, Irina Nunes, Baltazar |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Escola Nacional de Saúde Pública (ENSP) RUN |
dc.contributor.author.fl_str_mv |
Kissling, Esther Hooiveld, Mariette Martinez-Baz, Ivan Mazagatos, Clara William, Naoma Vilcu, Ana Maria Kooijman, Marjolein N. Ilic, Maja Domegan, Lisa Machado, Ausenda De Lusignan, Simon Lazar, Mihaela Meijer, Adam Brytting, Mia Casado, Itziar Larrauri, Amparo Murray, Josephine L.K. Behillil, Sylvie De Gier, Brechje Mlinaric, Ivan O'Donnell, Joan Rodrigues, Ana Paula Tsang, Ruby Timnea, Olivia De Lange, Marit Riess, Maximilian Castilla, Jesus Pozo, Francisco Hamilton, Mark Falchi, Alessandra Knol, Mirjam J. Filipovic, Sanja Kurecic Dunford, Linda Guiomar, Raquel Cogdale, Jade Cherciu, Carmen Jansen, Tessa Enkirch, Theresa Basile, Luca Connell, Jeff Gomez, Veronica Martin, Virginia Sandonis Bacci, Sabrina Rose, Angela M.C. Celentano, Lucia Pastore Valenciano, Marta Kislaya, Irina Nunes, Baltazar |
dc.subject.por.fl_str_mv |
Epidemiology Public Health, Environmental and Occupational Health Virology SDG 3 - Good Health and Well-being |
topic |
Epidemiology Public Health, Environmental and Occupational Health Virology SDG 3 - Good Health and Well-being |
description |
Funding Information: This project received funding from the European Centre for Disease Prevention and Control (ECDC) under the contract ECD.11486. Funding Information: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101003673. Publisher Copyright: © 2022 European Centre for Disease Prevention and Control (ECDC). All rights reserved. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-05-26 2022-05-26T00:00:00Z 2023-02-20T22:20:29Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/149492 |
url |
http://hdl.handle.net/10362/149492 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1025-496X PURE: 53859097 https://doi.org/10.2807/1560-7917.ES.2022.27.21.2101104 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799138127368945664 |