Association between physical activity and mortality in end-stage kidney disease

Detalhes bibliográficos
Autor(a) principal: Martins, Pedro
Data de Publicação: 2021
Outros Autores: Marques, Elisa A., Leal, Diogo V., Ferreira, Aníbal, Wilund, Kenneth R., Viana, João L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/120546
Resumo: Funding: Research Center in Sports Sciences, Health Sciences and Human Development, CIDESD, is supported by the Portuguese Foundation of Science and Technology (UID/04045/2020)
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spelling Association between physical activity and mortality in end-stage kidney diseasea systematic review of observational studiesChronic Kidney DiseaseHemodialysisHospitalizationPhysical ActivitySurvivalNephrologyFunding: Research Center in Sports Sciences, Health Sciences and Human Development, CIDESD, is supported by the Portuguese Foundation of Science and Technology (UID/04045/2020)Background: End-stage Kidney Disease patients have a high mortality and hospitalization risk. The association of these outcomes with physical activity is described in the general population and in other chronic diseases. However, few studies examining this association have been completed in end-stage Kidney Disease patients, raising the need to systematically review the evidence on the association of physical activity with mortality and hospitalization in this population. Methods: Electronic databases (EBSCO, Scopus and Web of Science) and hand search were performed until March 2020 for observational studies reporting the association of physical activity with mortality or hospitalization in adult end-stage Kidney Disease patients on renal replacement therapy (hemodialysis, peritoneal dialysis and kidney transplant). Methodological quality of the included studies was assessed using the Quality in Prognosis Studies tool. The review protocol was registered in PROSPERO (CRD42020155591). Results: Eleven studies were included: six in hemodialysis, three in kidney transplant, and two in hemodialysis and peritoneal dialysis patients. Physical activity was self-reported, except in one study that used accelerometers. All-cause mortality was addressed in all studies and cardiovascular mortality in three studies. Nine studies reported a significant reduction in all-cause mortality with increased levels of physical activity. Evidence of a dose-response relationship was found. For cardiovascular mortality, a significant reduction was observed in two of the three studies. Only one study investigated the association of physical activity with hospitalization. Conclusions: Higher physical activity was associated with reduced mortality in end-stage Kidney Disease patients. Future studies using objective physical activity measures could strengthen these findings. The association of physical activity with hospitalization should be explored in future investigations.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNMartins, PedroMarques, Elisa A.Leal, Diogo V.Ferreira, AníbalWilund, Kenneth R.Viana, João L.2021-07-05T22:18:21Z2021-06-182021-06-18T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/120546eng1471-2369PURE: 32161376https://doi.org/10.1186/s12882-021-02407-winfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:03:03Zoai:run.unl.pt:10362/120546Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:44:22.888750Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Association between physical activity and mortality in end-stage kidney disease
a systematic review of observational studies
title Association between physical activity and mortality in end-stage kidney disease
spellingShingle Association between physical activity and mortality in end-stage kidney disease
Martins, Pedro
Chronic Kidney Disease
Hemodialysis
Hospitalization
Physical Activity
Survival
Nephrology
title_short Association between physical activity and mortality in end-stage kidney disease
title_full Association between physical activity and mortality in end-stage kidney disease
title_fullStr Association between physical activity and mortality in end-stage kidney disease
title_full_unstemmed Association between physical activity and mortality in end-stage kidney disease
title_sort Association between physical activity and mortality in end-stage kidney disease
author Martins, Pedro
author_facet Martins, Pedro
Marques, Elisa A.
Leal, Diogo V.
Ferreira, Aníbal
Wilund, Kenneth R.
Viana, João L.
author_role author
author2 Marques, Elisa A.
Leal, Diogo V.
Ferreira, Aníbal
Wilund, Kenneth R.
Viana, João L.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Martins, Pedro
Marques, Elisa A.
Leal, Diogo V.
Ferreira, Aníbal
Wilund, Kenneth R.
Viana, João L.
dc.subject.por.fl_str_mv Chronic Kidney Disease
Hemodialysis
Hospitalization
Physical Activity
Survival
Nephrology
topic Chronic Kidney Disease
Hemodialysis
Hospitalization
Physical Activity
Survival
Nephrology
description Funding: Research Center in Sports Sciences, Health Sciences and Human Development, CIDESD, is supported by the Portuguese Foundation of Science and Technology (UID/04045/2020)
publishDate 2021
dc.date.none.fl_str_mv 2021-07-05T22:18:21Z
2021-06-18
2021-06-18T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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url http://hdl.handle.net/10362/120546
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1471-2369
PURE: 32161376
https://doi.org/10.1186/s12882-021-02407-w
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