Emerging trends in pharmaceutical manufacturing technology

Detalhes bibliográficos
Autor(a) principal: Barata, Maria Inês Carvalho Versos
Data de Publicação: 2015
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/30356
Resumo: Dissertação de mestrado em Biotecnologia Farmacêutica, apresentada à Faculdade de Farmácia da Universidade de Coimbra
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spelling Emerging trends in pharmaceutical manufacturing technologyTecnologia farmacêuticaIndústria farmacêuticaDissertação de mestrado em Biotecnologia Farmacêutica, apresentada à Faculdade de Farmácia da Universidade de CoimbraWith the extremely high average development costs of innovative medicines, the pharmaceutical industry faces unprecedented challenges and is under constant pressure to optimize the drug development process, as consequence of increased competition and healthcare costs. Rapid development of the emerging markets, progress in drug research, the rise in generics production, the availability of high-potency drugs and innovation in manufacturing process will sustainably modify the global pharmaceutical landscape. Thus, the global process of pharmaceutical innovation is not only focused on developing new drug entities but also in new manufacturing processes, that can optimize this stage of drug development, making it more efficient and cost-effective, responding to felt needs in the pharmaceutical sector. Improvements in process product development approaches and streamlining of manufacturing operations can have a profound impact on the bottomline. To keep pace with advances of new formulations and the increasing number of highly potent drugs, and so on, engineering expertise is required to design equipment that can manufacture, and package such medicines according to the required specifications while ensuring the safety of the workers. The aim of this study is to describe new manufacturing processes used in the pharmaceutical industry with particular interest in the following techniques: Fluidized Hot Melt Granulation, Hot Melt Extrusion, Spray Drying Technology, Liquid Dispensing Technology and DiffCORE Technology. For each one of these manufacturing techniques, a description of the state of the art is given and the pharmaceutical applications, the equipment, the excipients and the advantages and limitations are described2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesishttp://hdl.handle.net/10316/30356http://hdl.handle.net/10316/30356TID:201656396engBarata, Maria Inês Carvalho Versosinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-01-20T17:48:40Zoai:estudogeral.uc.pt:10316/30356Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:47:41.891683Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Emerging trends in pharmaceutical manufacturing technology
title Emerging trends in pharmaceutical manufacturing technology
spellingShingle Emerging trends in pharmaceutical manufacturing technology
Barata, Maria Inês Carvalho Versos
Tecnologia farmacêutica
Indústria farmacêutica
title_short Emerging trends in pharmaceutical manufacturing technology
title_full Emerging trends in pharmaceutical manufacturing technology
title_fullStr Emerging trends in pharmaceutical manufacturing technology
title_full_unstemmed Emerging trends in pharmaceutical manufacturing technology
title_sort Emerging trends in pharmaceutical manufacturing technology
author Barata, Maria Inês Carvalho Versos
author_facet Barata, Maria Inês Carvalho Versos
author_role author
dc.contributor.author.fl_str_mv Barata, Maria Inês Carvalho Versos
dc.subject.por.fl_str_mv Tecnologia farmacêutica
Indústria farmacêutica
topic Tecnologia farmacêutica
Indústria farmacêutica
description Dissertação de mestrado em Biotecnologia Farmacêutica, apresentada à Faculdade de Farmácia da Universidade de Coimbra
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/30356
http://hdl.handle.net/10316/30356
TID:201656396
url http://hdl.handle.net/10316/30356
identifier_str_mv TID:201656396
dc.language.iso.fl_str_mv eng
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