Prevalence of hepatitis E virus antibodies in workers occupationally exposed to swine in Portugal

Detalhes bibliográficos
Autor(a) principal: Teixeira, J.
Data de Publicação: 2016
Outros Autores: Mesquita, J. R., Pereira, S. S., Oliveira, R. M. S., Abreu-Silva, Joana, Rodrigues, A., Myrmel, M., Stene-Johansen, K., Øverbø, J., Gonçalves, G., Nascimento, M. S. J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.19/3588
Resumo: The concept of zoonotic hepatitis E in industrialized countries has emerged with the discovery of swine strains of hepatitis E virus (HEV) genotype 3, closely related to human HEV. Different routes of zoonotic HEV transmission have been recognized, including contact with infected pigs. Workers occupationally exposed to swine (WOES) have been considered a risk group for HEV infection, but contradictory results have been reported. In the present study, we searched for anti-HEV IgG in WOES (butchers, slaughterhouse workers, veterinarians and pig farmers; n = 114) and in the general population (n = 804) in order to investigate the potential occupational risk of zoonotic HEV infection in this work group. A significantly higher (p = 0.008) anti-HEV IgG seroprevalence was found in WOES (30.7 %) when compared with the general population (19.9 %). Multivariate analysis showed that having professions with exposure to pigs for more than 16.5 years was a risk factor for being positive for anti-HEV IgG (aOR of 5.4, 95 % CI 1.9-15.6, p = 0.002). To our knowledge, this is the first study on the prevalence of anti-HEV IgG in WOES in Portugal, also showing increased probability for infection in this group.
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spelling Prevalence of hepatitis E virus antibodies in workers occupationally exposed to swine in PortugalThe concept of zoonotic hepatitis E in industrialized countries has emerged with the discovery of swine strains of hepatitis E virus (HEV) genotype 3, closely related to human HEV. Different routes of zoonotic HEV transmission have been recognized, including contact with infected pigs. Workers occupationally exposed to swine (WOES) have been considered a risk group for HEV infection, but contradictory results have been reported. In the present study, we searched for anti-HEV IgG in WOES (butchers, slaughterhouse workers, veterinarians and pig farmers; n = 114) and in the general population (n = 804) in order to investigate the potential occupational risk of zoonotic HEV infection in this work group. A significantly higher (p = 0.008) anti-HEV IgG seroprevalence was found in WOES (30.7 %) when compared with the general population (19.9 %). Multivariate analysis showed that having professions with exposure to pigs for more than 16.5 years was a risk factor for being positive for anti-HEV IgG (aOR of 5.4, 95 % CI 1.9-15.6, p = 0.002). To our knowledge, this is the first study on the prevalence of anti-HEV IgG in WOES in Portugal, also showing increased probability for infection in this group.SpringerRepositório Científico do Instituto Politécnico de ViseuTeixeira, J.Mesquita, J. R.Pereira, S. S.Oliveira, R. M. S.Abreu-Silva, JoanaRodrigues, A.Myrmel, M.Stene-Johansen, K.Øverbø, J.Gonçalves, G.Nascimento, M. S. J.2017-01-03T13:30:11Z20162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.19/3588eng10.1007/s00430-016-0484-8info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-01-16T15:26:54Zoai:repositorio.ipv.pt:10400.19/3588Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:42:36.444462Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Prevalence of hepatitis E virus antibodies in workers occupationally exposed to swine in Portugal
title Prevalence of hepatitis E virus antibodies in workers occupationally exposed to swine in Portugal
spellingShingle Prevalence of hepatitis E virus antibodies in workers occupationally exposed to swine in Portugal
Teixeira, J.
title_short Prevalence of hepatitis E virus antibodies in workers occupationally exposed to swine in Portugal
title_full Prevalence of hepatitis E virus antibodies in workers occupationally exposed to swine in Portugal
title_fullStr Prevalence of hepatitis E virus antibodies in workers occupationally exposed to swine in Portugal
title_full_unstemmed Prevalence of hepatitis E virus antibodies in workers occupationally exposed to swine in Portugal
title_sort Prevalence of hepatitis E virus antibodies in workers occupationally exposed to swine in Portugal
author Teixeira, J.
author_facet Teixeira, J.
Mesquita, J. R.
Pereira, S. S.
Oliveira, R. M. S.
Abreu-Silva, Joana
Rodrigues, A.
Myrmel, M.
Stene-Johansen, K.
Øverbø, J.
Gonçalves, G.
Nascimento, M. S. J.
author_role author
author2 Mesquita, J. R.
Pereira, S. S.
Oliveira, R. M. S.
Abreu-Silva, Joana
Rodrigues, A.
Myrmel, M.
Stene-Johansen, K.
Øverbø, J.
Gonçalves, G.
Nascimento, M. S. J.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico de Viseu
dc.contributor.author.fl_str_mv Teixeira, J.
Mesquita, J. R.
Pereira, S. S.
Oliveira, R. M. S.
Abreu-Silva, Joana
Rodrigues, A.
Myrmel, M.
Stene-Johansen, K.
Øverbø, J.
Gonçalves, G.
Nascimento, M. S. J.
description The concept of zoonotic hepatitis E in industrialized countries has emerged with the discovery of swine strains of hepatitis E virus (HEV) genotype 3, closely related to human HEV. Different routes of zoonotic HEV transmission have been recognized, including contact with infected pigs. Workers occupationally exposed to swine (WOES) have been considered a risk group for HEV infection, but contradictory results have been reported. In the present study, we searched for anti-HEV IgG in WOES (butchers, slaughterhouse workers, veterinarians and pig farmers; n = 114) and in the general population (n = 804) in order to investigate the potential occupational risk of zoonotic HEV infection in this work group. A significantly higher (p = 0.008) anti-HEV IgG seroprevalence was found in WOES (30.7 %) when compared with the general population (19.9 %). Multivariate analysis showed that having professions with exposure to pigs for more than 16.5 years was a risk factor for being positive for anti-HEV IgG (aOR of 5.4, 95 % CI 1.9-15.6, p = 0.002). To our knowledge, this is the first study on the prevalence of anti-HEV IgG in WOES in Portugal, also showing increased probability for infection in this group.
publishDate 2016
dc.date.none.fl_str_mv 2016
2016-01-01T00:00:00Z
2017-01-03T13:30:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.19/3588
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dc.language.iso.fl_str_mv eng
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dc.publisher.none.fl_str_mv Springer
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