Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder: is there a role for microbiota in differential diagnosis? A comprehensive review
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Tipo de documento: | Dissertação |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/10216/142103 |
Resumo: | The differential diagnosis between Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) has always been a challenge. Insufficient diagnostic accuracy contributes to the difficulty to distinguish them associated with high comorbidity and similarity. Recently, there has been an increase in the number of scientific publications referring that the analysis of the bacterial content present in the gut, the microbiota, can be a fundamental diagnostic tool in neurodevelopmental disorders. The present review aims to confirm the presence of specific gut microbial communities in each of these pathologies, its relationship with disease symptoms and the role of microbiota in the differential diagnosis of ASD and ADHD. However, in ASD and ADHD it is clear that a relationship between each of the pathologies individually and the microbiota exists. These neurodevelopmental disorders have many symptoms in common, they can occur separately or as a co-morbidity of each other, and the means of diagnosis existing are all subjective (clinical criteria, scales, questionnaires, etc.) not allowing us to make an infallible diagnosis. Hence, in order to distinguish these pathologies, a more objective diagnostic criterion is needed, such as the analysis of the gut microbiota. |
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Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder: is there a role for microbiota in differential diagnosis? A comprehensive reviewCiências médicas e da saúdeMedical and Health sciencesThe differential diagnosis between Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) has always been a challenge. Insufficient diagnostic accuracy contributes to the difficulty to distinguish them associated with high comorbidity and similarity. Recently, there has been an increase in the number of scientific publications referring that the analysis of the bacterial content present in the gut, the microbiota, can be a fundamental diagnostic tool in neurodevelopmental disorders. The present review aims to confirm the presence of specific gut microbial communities in each of these pathologies, its relationship with disease symptoms and the role of microbiota in the differential diagnosis of ASD and ADHD. However, in ASD and ADHD it is clear that a relationship between each of the pathologies individually and the microbiota exists. These neurodevelopmental disorders have many symptoms in common, they can occur separately or as a co-morbidity of each other, and the means of diagnosis existing are all subjective (clinical criteria, scales, questionnaires, etc.) not allowing us to make an infallible diagnosis. Hence, in order to distinguish these pathologies, a more objective diagnostic criterion is needed, such as the analysis of the gut microbiota.2022-05-112022-05-11T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://hdl.handle.net/10216/142103TID:203177827engIvan Miranda Ramosinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T13:40:43Zoai:repositorio-aberto.up.pt:10216/142103Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:45:29.585370Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder: is there a role for microbiota in differential diagnosis? A comprehensive review |
title |
Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder: is there a role for microbiota in differential diagnosis? A comprehensive review |
spellingShingle |
Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder: is there a role for microbiota in differential diagnosis? A comprehensive review Ivan Miranda Ramos Ciências médicas e da saúde Medical and Health sciences |
title_short |
Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder: is there a role for microbiota in differential diagnosis? A comprehensive review |
title_full |
Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder: is there a role for microbiota in differential diagnosis? A comprehensive review |
title_fullStr |
Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder: is there a role for microbiota in differential diagnosis? A comprehensive review |
title_full_unstemmed |
Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder: is there a role for microbiota in differential diagnosis? A comprehensive review |
title_sort |
Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder: is there a role for microbiota in differential diagnosis? A comprehensive review |
author |
Ivan Miranda Ramos |
author_facet |
Ivan Miranda Ramos |
author_role |
author |
dc.contributor.author.fl_str_mv |
Ivan Miranda Ramos |
dc.subject.por.fl_str_mv |
Ciências médicas e da saúde Medical and Health sciences |
topic |
Ciências médicas e da saúde Medical and Health sciences |
description |
The differential diagnosis between Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) has always been a challenge. Insufficient diagnostic accuracy contributes to the difficulty to distinguish them associated with high comorbidity and similarity. Recently, there has been an increase in the number of scientific publications referring that the analysis of the bacterial content present in the gut, the microbiota, can be a fundamental diagnostic tool in neurodevelopmental disorders. The present review aims to confirm the presence of specific gut microbial communities in each of these pathologies, its relationship with disease symptoms and the role of microbiota in the differential diagnosis of ASD and ADHD. However, in ASD and ADHD it is clear that a relationship between each of the pathologies individually and the microbiota exists. These neurodevelopmental disorders have many symptoms in common, they can occur separately or as a co-morbidity of each other, and the means of diagnosis existing are all subjective (clinical criteria, scales, questionnaires, etc.) not allowing us to make an infallible diagnosis. Hence, in order to distinguish these pathologies, a more objective diagnostic criterion is needed, such as the analysis of the gut microbiota. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-05-11 2022-05-11T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/10216/142103 TID:203177827 |
url |
https://hdl.handle.net/10216/142103 |
identifier_str_mv |
TID:203177827 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799135771480817664 |