Clinical Characteristics of Frontal Fibrosing Alopecia in Brazil: A Series of 59 Patients

Detalhes bibliográficos
Autor(a) principal: Barreto Rocha, Vanessa
Data de Publicação: 2020
Outros Autores: Arse Contin, Leticia, Kakizaki, Priscila, Jorge Machado, Carla, Pires, Mário Cézar, Vasconcellos, Cidia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.77.4.1119
Resumo: Introduction: Clinical characteristics of frontal fibrosing alopecia (FFA) have been studied since its description in 1994 in Europe, North America and Australia, and the present study is the largest on FFA features in Latin America. Methods: This study, through questionnaire and medical records, describes characteristics of a Brazilian population of 59 patients with FFA, concerning clinical forms, individual features and use of cosmetic products. Results: Mean patients’ age was 58.4 years (range 35-84y). Duration of disease varied from six months to 20y (median 5y). Most women were postmenopausal (83.1%) and non-smokers (83.1%). Five percent had at least one associated autoimmune disease, most commonly hypothyroidism (13.6%). Six of 40 patients (15%) had lichen planus pigmentosus and ten had facial papules (25%). Eyebrow alopecia occurred in 50 (84.7%), and body hair loss in 47 (79.7%). Facial papules were more prevalent in premenopausal women. Conclusion: Studying FFA epide- miology may help understanding the pathophysiology of this epidemic disease and this study highlights similarities and differences to previously published studies in FFA, such as greater frequency in postmenopausal women, association with hypothyroidism and facial irritation with cosmetic products.
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spelling Clinical Characteristics of Frontal Fibrosing Alopecia in Brazil: A Series of 59 PatientsCaracterísticas Clínicas da Alopecia Frontal Fibrosante no Brasil: Série de 59 PacientesAlopecia/epidemiologyBrazilLichen PlanusAlopecia/epidemiologiaBrasilLíquen PlanoIntroduction: Clinical characteristics of frontal fibrosing alopecia (FFA) have been studied since its description in 1994 in Europe, North America and Australia, and the present study is the largest on FFA features in Latin America. Methods: This study, through questionnaire and medical records, describes characteristics of a Brazilian population of 59 patients with FFA, concerning clinical forms, individual features and use of cosmetic products. Results: Mean patients’ age was 58.4 years (range 35-84y). Duration of disease varied from six months to 20y (median 5y). Most women were postmenopausal (83.1%) and non-smokers (83.1%). Five percent had at least one associated autoimmune disease, most commonly hypothyroidism (13.6%). Six of 40 patients (15%) had lichen planus pigmentosus and ten had facial papules (25%). Eyebrow alopecia occurred in 50 (84.7%), and body hair loss in 47 (79.7%). Facial papules were more prevalent in premenopausal women. Conclusion: Studying FFA epide- miology may help understanding the pathophysiology of this epidemic disease and this study highlights similarities and differences to previously published studies in FFA, such as greater frequency in postmenopausal women, association with hypothyroidism and facial irritation with cosmetic products.Introdução: A alopecia frontal fibrosante (AFF) foi inicialmente descrita em 1994 na Austrália, Europa e América do Norte, e este é o maior estudo sobre as características da AFF na América Latina. Métodos: Através de questionários e revisão dos processos clínicos, descrevemos as características de 59 pacientes com AFF, quanto à forma clínica, características indivi- duais e uso de produtos cosméticos. Resultados: A idade média dos pacientes foi de 58,4 anos (35-84 anos). A duração da doença variou de seis meses a 20 anos (mediana 5 anos). A maioria das mulheres encontrava-se na menopausa e (83,1%) e era não fumadora (83,1%). Cinco por cento tinham pelo menos uma doença autoimune associada, principalmente hipotireoidis- mo (13,6%). Seis pacientes (15%) apresentavam líquen plano pigmentoso e dez pápulas faciais (25%). Alopecia dos supracílios ocorreu em 50 (84,7%) e no corpo em 47 (79,7%). Pápulas faciais foram mais prevalentes em mulheres na pré-menopausa. Conclusão: Estudar a epidemiologia da AFF pode ajudar a entender a fisiopatologia dessa doença epidémica e este artigo traz algumas semelhanças e diferenças com estudos publicados anteriormente sobre a AFF, como maior frequência em mulheres na pós-menopausa, associação com hipotireoidismo e irritação facial com o uso de produtos cosméticos.Sociedade Portuguesa de Dermatologia e Venereologia2020-01-11T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.77.4.1119oai:ojs.revista.spdv.com.pt:article/1119Journal of the Portuguese Society of Dermatology and Venereology; Vol 77 No 4 (2019): October - December; 315-322Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 77 n. 4 (2019): Outubro - Dezembro; 315-3222182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://revista.spdv.com.pt/index.php/spdv/article/view/1119https://doi.org/10.29021/spdv.77.4.1119https://revista.spdv.com.pt/index.php/spdv/article/view/1119/802Barreto Rocha, VanessaArse Contin, LeticiaKakizaki, PriscilaJorge Machado, CarlaPires, Mário CézarVasconcellos, Cidiainfo:eu-repo/semantics/openAccess2022-10-06T12:35:12Zoai:ojs.revista.spdv.com.pt:article/1119Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:11.270140Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Clinical Characteristics of Frontal Fibrosing Alopecia in Brazil: A Series of 59 Patients
Características Clínicas da Alopecia Frontal Fibrosante no Brasil: Série de 59 Pacientes
title Clinical Characteristics of Frontal Fibrosing Alopecia in Brazil: A Series of 59 Patients
spellingShingle Clinical Characteristics of Frontal Fibrosing Alopecia in Brazil: A Series of 59 Patients
Barreto Rocha, Vanessa
Alopecia/epidemiology
Brazil
Lichen Planus
Alopecia/epidemiologia
Brasil
Líquen Plano
title_short Clinical Characteristics of Frontal Fibrosing Alopecia in Brazil: A Series of 59 Patients
title_full Clinical Characteristics of Frontal Fibrosing Alopecia in Brazil: A Series of 59 Patients
title_fullStr Clinical Characteristics of Frontal Fibrosing Alopecia in Brazil: A Series of 59 Patients
title_full_unstemmed Clinical Characteristics of Frontal Fibrosing Alopecia in Brazil: A Series of 59 Patients
title_sort Clinical Characteristics of Frontal Fibrosing Alopecia in Brazil: A Series of 59 Patients
author Barreto Rocha, Vanessa
author_facet Barreto Rocha, Vanessa
Arse Contin, Leticia
Kakizaki, Priscila
Jorge Machado, Carla
Pires, Mário Cézar
Vasconcellos, Cidia
author_role author
author2 Arse Contin, Leticia
Kakizaki, Priscila
Jorge Machado, Carla
Pires, Mário Cézar
Vasconcellos, Cidia
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Barreto Rocha, Vanessa
Arse Contin, Leticia
Kakizaki, Priscila
Jorge Machado, Carla
Pires, Mário Cézar
Vasconcellos, Cidia
dc.subject.por.fl_str_mv Alopecia/epidemiology
Brazil
Lichen Planus
Alopecia/epidemiologia
Brasil
Líquen Plano
topic Alopecia/epidemiology
Brazil
Lichen Planus
Alopecia/epidemiologia
Brasil
Líquen Plano
description Introduction: Clinical characteristics of frontal fibrosing alopecia (FFA) have been studied since its description in 1994 in Europe, North America and Australia, and the present study is the largest on FFA features in Latin America. Methods: This study, through questionnaire and medical records, describes characteristics of a Brazilian population of 59 patients with FFA, concerning clinical forms, individual features and use of cosmetic products. Results: Mean patients’ age was 58.4 years (range 35-84y). Duration of disease varied from six months to 20y (median 5y). Most women were postmenopausal (83.1%) and non-smokers (83.1%). Five percent had at least one associated autoimmune disease, most commonly hypothyroidism (13.6%). Six of 40 patients (15%) had lichen planus pigmentosus and ten had facial papules (25%). Eyebrow alopecia occurred in 50 (84.7%), and body hair loss in 47 (79.7%). Facial papules were more prevalent in premenopausal women. Conclusion: Studying FFA epide- miology may help understanding the pathophysiology of this epidemic disease and this study highlights similarities and differences to previously published studies in FFA, such as greater frequency in postmenopausal women, association with hypothyroidism and facial irritation with cosmetic products.
publishDate 2020
dc.date.none.fl_str_mv 2020-01-11T00:00:00Z
dc.type.driver.fl_str_mv journal article
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dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.77.4.1119
oai:ojs.revista.spdv.com.pt:article/1119
url https://doi.org/10.29021/spdv.77.4.1119
identifier_str_mv oai:ojs.revista.spdv.com.pt:article/1119
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/1119
https://doi.org/10.29021/spdv.77.4.1119
https://revista.spdv.com.pt/index.php/spdv/article/view/1119/802
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 77 No 4 (2019): October - December; 315-322
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 77 n. 4 (2019): Outubro - Dezembro; 315-322
2182-2409
2182-2395
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