Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications

Detalhes bibliográficos
Autor(a) principal: Taheri, Y
Data de Publicação: 2020
Outros Autores: Suleria, HAR, Martins, N, Sytar, O, Beyatli, A, Yeskaliyeva, B, Seitimova, G, Salehi, B, Semwal, P, Painuli, S, Kumar, A, Azzini, E, Martorell, M, Setzer, WN, Maroyi, A, Sharifi-Rad, J
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/143534
Resumo: Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.
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spelling Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applicationsAntimicrobialAntioxidantCancerCardiovascular diseaseDiabetesImmunomodulatoryMyricetinNeuroprotectionSeveral flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.BMC20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/143534eng2662-767110.1186/s12906-020-03033-zTaheri, YSuleria, HARMartins, NSytar, OBeyatli, AYeskaliyeva, BSeitimova, GSalehi, BSemwal, PPainuli, SKumar, AAzzini, EMartorell, MSetzer, WNMaroyi, ASharifi-Rad, Jinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T15:03:15Zoai:repositorio-aberto.up.pt:10216/143534Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:14:33.124926Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications
title Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications
spellingShingle Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications
Taheri, Y
Antimicrobial
Antioxidant
Cancer
Cardiovascular disease
Diabetes
Immunomodulatory
Myricetin
Neuroprotection
title_short Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications
title_full Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications
title_fullStr Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications
title_full_unstemmed Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications
title_sort Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications
author Taheri, Y
author_facet Taheri, Y
Suleria, HAR
Martins, N
Sytar, O
Beyatli, A
Yeskaliyeva, B
Seitimova, G
Salehi, B
Semwal, P
Painuli, S
Kumar, A
Azzini, E
Martorell, M
Setzer, WN
Maroyi, A
Sharifi-Rad, J
author_role author
author2 Suleria, HAR
Martins, N
Sytar, O
Beyatli, A
Yeskaliyeva, B
Seitimova, G
Salehi, B
Semwal, P
Painuli, S
Kumar, A
Azzini, E
Martorell, M
Setzer, WN
Maroyi, A
Sharifi-Rad, J
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Taheri, Y
Suleria, HAR
Martins, N
Sytar, O
Beyatli, A
Yeskaliyeva, B
Seitimova, G
Salehi, B
Semwal, P
Painuli, S
Kumar, A
Azzini, E
Martorell, M
Setzer, WN
Maroyi, A
Sharifi-Rad, J
dc.subject.por.fl_str_mv Antimicrobial
Antioxidant
Cancer
Cardiovascular disease
Diabetes
Immunomodulatory
Myricetin
Neuroprotection
topic Antimicrobial
Antioxidant
Cancer
Cardiovascular disease
Diabetes
Immunomodulatory
Myricetin
Neuroprotection
description Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/10216/143534
url https://hdl.handle.net/10216/143534
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2662-7671
10.1186/s12906-020-03033-z
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BMC
publisher.none.fl_str_mv BMC
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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