Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.8/5998 |
Resumo: | This work was supported by National Funds through FCT/ MCTES – Portuguese Foundation for Science and Technology within the scope of the projects UID/QUI/0619/2019, UIDB/ 50006/2020 (LAQV-REQUIMTE) and UIDB/00100/2020, UID/ MAR/04292/2020 (MARE—Marine and Environmental Sciences Centre). Also, a doctoral fellowship to Andreia Forte (PD/BD/ 109625/2015) and Solchemar company are acknowledged. The NMR spectrometers are part of The National NMR Facility, supported by FCT/MCTES (RECI/BBB-BQB/0230/2012). |
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Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studiesThis work was supported by National Funds through FCT/ MCTES – Portuguese Foundation for Science and Technology within the scope of the projects UID/QUI/0619/2019, UIDB/ 50006/2020 (LAQV-REQUIMTE) and UIDB/00100/2020, UID/ MAR/04292/2020 (MARE—Marine and Environmental Sciences Centre). Also, a doctoral fellowship to Andreia Forte (PD/BD/ 109625/2015) and Solchemar company are acknowledged. The NMR spectrometers are part of The National NMR Facility, supported by FCT/MCTES (RECI/BBB-BQB/0230/2012).Several organic salts based on the combination of two different choline derivative cations and MnCl3−, GdCl4− and TbCl4− as anions were immobilized in mesoporous silica nanoparticles (MSNs) by a two-step synthetic method. Firstly, MSNs were functionalized with choline derivative cations with chloride anions and then the metals were incorporated by the reaction of the chloride with the respective metal chloride salts. These nanomaterials were fully characterized by different characterization techniques such as 1H-NMR, FT-IR, elemental analysis, TEM, TGA, N2 adsorption, XRD and DLS. These characterization data were important to confirm the successful functionalization of the nanomaterials and to access their textural properties and colloidal stability. The final materials were also characterized by ICP-MS that indicated the metal contents. The cytotoxicity profile was evaluated in four different cell lines (3T3, 293T, HepG2 and Caco-2), which shows some relevant differences between the metal organic salts and their immobilized analogues.Royal Society of ChemistryIC-OnlineForte, AndreiaGago, SandraCarrott, Manuela RibeiroCarrott, PeterAlves, CelsoTeodoro, FernandoPedrosa, RuiMarrucho, Isabel M.Branco, Luis C2021-08-03T15:17:23Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.8/5998engAndreia Forte; Sandra Gago; Manuela Ribeiro Carrott; Peter Carrott; Celso Alves; Fernando Teodoro; Rui Pedrosa; Isabel M. Marrucho; Luis C. Branco. "Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies". Dalton Transactions (2021): https://doi.org/10.1039/D1DT00605C.1477-922610.1039/D1DT00605Cmetadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-09-26T18:19:57Zoai:iconline.ipleiria.pt:10400.8/5998Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-09-26T18:19:57Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies |
title |
Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies |
spellingShingle |
Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies Forte, Andreia |
title_short |
Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies |
title_full |
Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies |
title_fullStr |
Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies |
title_full_unstemmed |
Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies |
title_sort |
Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies |
author |
Forte, Andreia |
author_facet |
Forte, Andreia Gago, Sandra Carrott, Manuela Ribeiro Carrott, Peter Alves, Celso Teodoro, Fernando Pedrosa, Rui Marrucho, Isabel M. Branco, Luis C |
author_role |
author |
author2 |
Gago, Sandra Carrott, Manuela Ribeiro Carrott, Peter Alves, Celso Teodoro, Fernando Pedrosa, Rui Marrucho, Isabel M. Branco, Luis C |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
IC-Online |
dc.contributor.author.fl_str_mv |
Forte, Andreia Gago, Sandra Carrott, Manuela Ribeiro Carrott, Peter Alves, Celso Teodoro, Fernando Pedrosa, Rui Marrucho, Isabel M. Branco, Luis C |
description |
This work was supported by National Funds through FCT/ MCTES – Portuguese Foundation for Science and Technology within the scope of the projects UID/QUI/0619/2019, UIDB/ 50006/2020 (LAQV-REQUIMTE) and UIDB/00100/2020, UID/ MAR/04292/2020 (MARE—Marine and Environmental Sciences Centre). Also, a doctoral fellowship to Andreia Forte (PD/BD/ 109625/2015) and Solchemar company are acknowledged. The NMR spectrometers are part of The National NMR Facility, supported by FCT/MCTES (RECI/BBB-BQB/0230/2012). |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-08-03T15:17:23Z 2021 2021-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.8/5998 |
url |
http://hdl.handle.net/10400.8/5998 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Andreia Forte; Sandra Gago; Manuela Ribeiro Carrott; Peter Carrott; Celso Alves; Fernando Teodoro; Rui Pedrosa; Isabel M. Marrucho; Luis C. Branco. "Mesoporous silica nanoparticles with manganese and lanthanide salts: synthesis, characterization and cytotoxicity studies". Dalton Transactions (2021): https://doi.org/10.1039/D1DT00605C. 1477-9226 10.1039/D1DT00605C |
dc.rights.driver.fl_str_mv |
metadata only access info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
metadata only access |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Royal Society of Chemistry |
publisher.none.fl_str_mv |
Royal Society of Chemistry |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
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1817547269181800448 |