Bone remodeling markers and bone metastases: from cancer research to clinical implications

Detalhes bibliográficos
Autor(a) principal: Ferreira, Arlindo
Data de Publicação: 2015
Outros Autores: Alho, Irina, Casimiro, Sandra, Costa, Luis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/49129
Resumo: © 2015 International Bone & Mineral Society All rights reserved.
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spelling Bone remodeling markers and bone metastases: from cancer research to clinical implications© 2015 International Bone & Mineral Society All rights reserved.Bone metastasis is a frequent finding in the natural history of several types of cancers. However, its anticipated risk, diagnosis and response to therapy are still challenging to assess in clinical practice. Markers of bone metabolism are biochemical by-products that provide insight into the tumor-bone interaction, with potential to enhance the clinical management of patients with bone metastases. In fact, these markers had a cornerstone role in the development of bone-targeted agents; however, its translation to routine practice is still unclear, as reflected by current international guidelines. In this review, we aimed to capture several of the research and clinical translational challenges regarding the use of bone metabolism markers that we consider relevant for future research in bone metastasis.International Bone & Mineral SocietyRepositório da Universidade de LisboaFerreira, ArlindoAlho, IrinaCasimiro, SandraCosta, Luis2021-07-26T15:16:47Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/49129engBonekey Rep. 2015 Apr 22;4:66810.1038/bonekey.2015.352047-6396info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:52:33Zoai:repositorio.ul.pt:10451/49129Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:00:42.732140Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bone remodeling markers and bone metastases: from cancer research to clinical implications
title Bone remodeling markers and bone metastases: from cancer research to clinical implications
spellingShingle Bone remodeling markers and bone metastases: from cancer research to clinical implications
Ferreira, Arlindo
title_short Bone remodeling markers and bone metastases: from cancer research to clinical implications
title_full Bone remodeling markers and bone metastases: from cancer research to clinical implications
title_fullStr Bone remodeling markers and bone metastases: from cancer research to clinical implications
title_full_unstemmed Bone remodeling markers and bone metastases: from cancer research to clinical implications
title_sort Bone remodeling markers and bone metastases: from cancer research to clinical implications
author Ferreira, Arlindo
author_facet Ferreira, Arlindo
Alho, Irina
Casimiro, Sandra
Costa, Luis
author_role author
author2 Alho, Irina
Casimiro, Sandra
Costa, Luis
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Ferreira, Arlindo
Alho, Irina
Casimiro, Sandra
Costa, Luis
description © 2015 International Bone & Mineral Society All rights reserved.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2021-07-26T15:16:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/49129
url http://hdl.handle.net/10451/49129
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Bonekey Rep. 2015 Apr 22;4:668
10.1038/bonekey.2015.35
2047-6396
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv International Bone & Mineral Society
publisher.none.fl_str_mv International Bone & Mineral Society
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
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