Bone remodeling markers and bone metastases: from cancer research to clinical implications
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10451/49129 |
Resumo: | © 2015 International Bone & Mineral Society All rights reserved. |
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Bone remodeling markers and bone metastases: from cancer research to clinical implications© 2015 International Bone & Mineral Society All rights reserved.Bone metastasis is a frequent finding in the natural history of several types of cancers. However, its anticipated risk, diagnosis and response to therapy are still challenging to assess in clinical practice. Markers of bone metabolism are biochemical by-products that provide insight into the tumor-bone interaction, with potential to enhance the clinical management of patients with bone metastases. In fact, these markers had a cornerstone role in the development of bone-targeted agents; however, its translation to routine practice is still unclear, as reflected by current international guidelines. In this review, we aimed to capture several of the research and clinical translational challenges regarding the use of bone metabolism markers that we consider relevant for future research in bone metastasis.International Bone & Mineral SocietyRepositório da Universidade de LisboaFerreira, ArlindoAlho, IrinaCasimiro, SandraCosta, Luis2021-07-26T15:16:47Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/49129engBonekey Rep. 2015 Apr 22;4:66810.1038/bonekey.2015.352047-6396info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:52:33Zoai:repositorio.ul.pt:10451/49129Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:00:42.732140Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Bone remodeling markers and bone metastases: from cancer research to clinical implications |
title |
Bone remodeling markers and bone metastases: from cancer research to clinical implications |
spellingShingle |
Bone remodeling markers and bone metastases: from cancer research to clinical implications Ferreira, Arlindo |
title_short |
Bone remodeling markers and bone metastases: from cancer research to clinical implications |
title_full |
Bone remodeling markers and bone metastases: from cancer research to clinical implications |
title_fullStr |
Bone remodeling markers and bone metastases: from cancer research to clinical implications |
title_full_unstemmed |
Bone remodeling markers and bone metastases: from cancer research to clinical implications |
title_sort |
Bone remodeling markers and bone metastases: from cancer research to clinical implications |
author |
Ferreira, Arlindo |
author_facet |
Ferreira, Arlindo Alho, Irina Casimiro, Sandra Costa, Luis |
author_role |
author |
author2 |
Alho, Irina Casimiro, Sandra Costa, Luis |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
dc.contributor.author.fl_str_mv |
Ferreira, Arlindo Alho, Irina Casimiro, Sandra Costa, Luis |
description |
© 2015 International Bone & Mineral Society All rights reserved. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015 2015-01-01T00:00:00Z 2021-07-26T15:16:47Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/49129 |
url |
http://hdl.handle.net/10451/49129 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Bonekey Rep. 2015 Apr 22;4:668 10.1038/bonekey.2015.35 2047-6396 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
International Bone & Mineral Society |
publisher.none.fl_str_mv |
International Bone & Mineral Society |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799134555618148352 |