Lepromatous Leprosy: Report of a Histoid-Like Case

Detalhes bibliográficos
Autor(a) principal: Rodrigues, Ana Carolina Serra
Data de Publicação: 2019
Outros Autores: Quintella, Danielle Carvalho, Rodrigues, Felipe Tavares, Pockstaller, Mercedes Prates, Nery, José Augusto da Costa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.77.1.962
Resumo: Histoid leprosy, described by Wade in 1963, represents an atypical variant of lepromatous leprosy, with its own clinical and pathological features. In the past, it was considered a marker of drug resistance and relapse. It presents as keloid-like plaque or nodular lesions. Optical microscopy shows few foamy macrophages and numerous alcohol-acid-resistant bacilli and an infiltrate composed predominantly of spindle cells, which can mimic fibrohistiocytic neoplasms. We report a case of lepromatous leprosy with lesions clinically compatible with the histoid variant in order to demonstrate and reinforce the clinical polymorphism of this type of Hansen’s disease and raise awareness for the need of an early diagnosis and treatment, therefore with the interruption of the transmission chain and reduction of the occurrence of irreversible leprosy-related disability.
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spelling Lepromatous Leprosy: Report of a Histoid-Like CaseHanseníase Lepromatosa: Relato de um Caso do Tipo Histióide-Símile.LeprosyLepromatousSkinHanseníase VirchowianaPeleHistoid leprosy, described by Wade in 1963, represents an atypical variant of lepromatous leprosy, with its own clinical and pathological features. In the past, it was considered a marker of drug resistance and relapse. It presents as keloid-like plaque or nodular lesions. Optical microscopy shows few foamy macrophages and numerous alcohol-acid-resistant bacilli and an infiltrate composed predominantly of spindle cells, which can mimic fibrohistiocytic neoplasms. We report a case of lepromatous leprosy with lesions clinically compatible with the histoid variant in order to demonstrate and reinforce the clinical polymorphism of this type of Hansen’s disease and raise awareness for the need of an early diagnosis and treatment, therefore with the interruption of the transmission chain and reduction of the occurrence of irreversible leprosy-related disability.A hanseníase históide representa uma forma atípica de apresentação da hanseníase virchowiana, descrita por Wade em 1963, com características clínicas e anatomopatológicas próprias, que no passado era considerada um marcador de resistência medicamentosa e recidiva. Clinicamente caracteriza-se por placas ou nodulos de aspecto queloidiforme. À microscopia óptica nota-se infiltrado predominantemente constituído por células fusiformes que por vezes simula neoplasia fibrohistiocítica, associada a poucos macrófagos espumosos e numerosos bacilos álcool-ácido-resistentes. Relata-se um caso de hanseníase virchowiana com lesões clinicamente compatíveis com a forma históide, a fim de demonstrar e reforçar o seu grande polimorfismo clínico e a importância do seu conhecimento para diagnóstico e tratamento precoce, para interromper a cadeia de transmissão e diminuir a ocorrência de incapacidades irreversíveis causadas pela doença.Sociedade Portuguesa de Dermatologia e Venereologia2019-03-26T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.77.1.962oai:ojs.revista.spdv.com.pt:article/962Journal of the Portuguese Society of Dermatology and Venereology; Vol 77 No 1 (2019): January / March; 73-76Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 77 n. 1 (2019): Janeiro / Março; 73-762182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/962https://doi.org/10.29021/spdv.77.1.962https://revista.spdv.com.pt/index.php/spdv/article/view/962/623Rodrigues, Ana Carolina SerraQuintella, Danielle CarvalhoRodrigues, Felipe TavaresPockstaller, Mercedes PratesNery, José Augusto da Costainfo:eu-repo/semantics/openAccess2022-10-06T12:35:09Zoai:ojs.revista.spdv.com.pt:article/962Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:07.957701Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Lepromatous Leprosy: Report of a Histoid-Like Case
Hanseníase Lepromatosa: Relato de um Caso do Tipo Histióide-Símile.
title Lepromatous Leprosy: Report of a Histoid-Like Case
spellingShingle Lepromatous Leprosy: Report of a Histoid-Like Case
Rodrigues, Ana Carolina Serra
Leprosy
Lepromatous
Skin
Hanseníase Virchowiana
Pele
title_short Lepromatous Leprosy: Report of a Histoid-Like Case
title_full Lepromatous Leprosy: Report of a Histoid-Like Case
title_fullStr Lepromatous Leprosy: Report of a Histoid-Like Case
title_full_unstemmed Lepromatous Leprosy: Report of a Histoid-Like Case
title_sort Lepromatous Leprosy: Report of a Histoid-Like Case
author Rodrigues, Ana Carolina Serra
author_facet Rodrigues, Ana Carolina Serra
Quintella, Danielle Carvalho
Rodrigues, Felipe Tavares
Pockstaller, Mercedes Prates
Nery, José Augusto da Costa
author_role author
author2 Quintella, Danielle Carvalho
Rodrigues, Felipe Tavares
Pockstaller, Mercedes Prates
Nery, José Augusto da Costa
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Rodrigues, Ana Carolina Serra
Quintella, Danielle Carvalho
Rodrigues, Felipe Tavares
Pockstaller, Mercedes Prates
Nery, José Augusto da Costa
dc.subject.por.fl_str_mv Leprosy
Lepromatous
Skin
Hanseníase Virchowiana
Pele
topic Leprosy
Lepromatous
Skin
Hanseníase Virchowiana
Pele
description Histoid leprosy, described by Wade in 1963, represents an atypical variant of lepromatous leprosy, with its own clinical and pathological features. In the past, it was considered a marker of drug resistance and relapse. It presents as keloid-like plaque or nodular lesions. Optical microscopy shows few foamy macrophages and numerous alcohol-acid-resistant bacilli and an infiltrate composed predominantly of spindle cells, which can mimic fibrohistiocytic neoplasms. We report a case of lepromatous leprosy with lesions clinically compatible with the histoid variant in order to demonstrate and reinforce the clinical polymorphism of this type of Hansen’s disease and raise awareness for the need of an early diagnosis and treatment, therefore with the interruption of the transmission chain and reduction of the occurrence of irreversible leprosy-related disability.
publishDate 2019
dc.date.none.fl_str_mv 2019-03-26T00:00:00Z
dc.type.driver.fl_str_mv journal article
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dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.77.1.962
oai:ojs.revista.spdv.com.pt:article/962
url https://doi.org/10.29021/spdv.77.1.962
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dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/962
https://doi.org/10.29021/spdv.77.1.962
https://revista.spdv.com.pt/index.php/spdv/article/view/962/623
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 77 No 1 (2019): January / March; 73-76
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 77 n. 1 (2019): Janeiro / Março; 73-76
2182-2409
2182-2395
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