Lepromatous Leprosy: Report of a Histoid-Like Case
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.29021/spdv.77.1.962 |
Resumo: | Histoid leprosy, described by Wade in 1963, represents an atypical variant of lepromatous leprosy, with its own clinical and pathological features. In the past, it was considered a marker of drug resistance and relapse. It presents as keloid-like plaque or nodular lesions. Optical microscopy shows few foamy macrophages and numerous alcohol-acid-resistant bacilli and an infiltrate composed predominantly of spindle cells, which can mimic fibrohistiocytic neoplasms. We report a case of lepromatous leprosy with lesions clinically compatible with the histoid variant in order to demonstrate and reinforce the clinical polymorphism of this type of Hansen’s disease and raise awareness for the need of an early diagnosis and treatment, therefore with the interruption of the transmission chain and reduction of the occurrence of irreversible leprosy-related disability. |
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Lepromatous Leprosy: Report of a Histoid-Like CaseHanseníase Lepromatosa: Relato de um Caso do Tipo Histióide-Símile.LeprosyLepromatousSkinHanseníase VirchowianaPeleHistoid leprosy, described by Wade in 1963, represents an atypical variant of lepromatous leprosy, with its own clinical and pathological features. In the past, it was considered a marker of drug resistance and relapse. It presents as keloid-like plaque or nodular lesions. Optical microscopy shows few foamy macrophages and numerous alcohol-acid-resistant bacilli and an infiltrate composed predominantly of spindle cells, which can mimic fibrohistiocytic neoplasms. We report a case of lepromatous leprosy with lesions clinically compatible with the histoid variant in order to demonstrate and reinforce the clinical polymorphism of this type of Hansen’s disease and raise awareness for the need of an early diagnosis and treatment, therefore with the interruption of the transmission chain and reduction of the occurrence of irreversible leprosy-related disability.A hanseníase históide representa uma forma atípica de apresentação da hanseníase virchowiana, descrita por Wade em 1963, com características clínicas e anatomopatológicas próprias, que no passado era considerada um marcador de resistência medicamentosa e recidiva. Clinicamente caracteriza-se por placas ou nodulos de aspecto queloidiforme. À microscopia óptica nota-se infiltrado predominantemente constituído por células fusiformes que por vezes simula neoplasia fibrohistiocítica, associada a poucos macrófagos espumosos e numerosos bacilos álcool-ácido-resistentes. Relata-se um caso de hanseníase virchowiana com lesões clinicamente compatíveis com a forma históide, a fim de demonstrar e reforçar o seu grande polimorfismo clínico e a importância do seu conhecimento para diagnóstico e tratamento precoce, para interromper a cadeia de transmissão e diminuir a ocorrência de incapacidades irreversíveis causadas pela doença.Sociedade Portuguesa de Dermatologia e Venereologia2019-03-26T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.77.1.962oai:ojs.revista.spdv.com.pt:article/962Journal of the Portuguese Society of Dermatology and Venereology; Vol 77 No 1 (2019): January / March; 73-76Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 77 n. 1 (2019): Janeiro / Março; 73-762182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/962https://doi.org/10.29021/spdv.77.1.962https://revista.spdv.com.pt/index.php/spdv/article/view/962/623Rodrigues, Ana Carolina SerraQuintella, Danielle CarvalhoRodrigues, Felipe TavaresPockstaller, Mercedes PratesNery, José Augusto da Costainfo:eu-repo/semantics/openAccess2022-10-06T12:35:09Zoai:ojs.revista.spdv.com.pt:article/962Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:07.957701Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Lepromatous Leprosy: Report of a Histoid-Like Case Hanseníase Lepromatosa: Relato de um Caso do Tipo Histióide-Símile. |
title |
Lepromatous Leprosy: Report of a Histoid-Like Case |
spellingShingle |
Lepromatous Leprosy: Report of a Histoid-Like Case Rodrigues, Ana Carolina Serra Leprosy Lepromatous Skin Hanseníase Virchowiana Pele |
title_short |
Lepromatous Leprosy: Report of a Histoid-Like Case |
title_full |
Lepromatous Leprosy: Report of a Histoid-Like Case |
title_fullStr |
Lepromatous Leprosy: Report of a Histoid-Like Case |
title_full_unstemmed |
Lepromatous Leprosy: Report of a Histoid-Like Case |
title_sort |
Lepromatous Leprosy: Report of a Histoid-Like Case |
author |
Rodrigues, Ana Carolina Serra |
author_facet |
Rodrigues, Ana Carolina Serra Quintella, Danielle Carvalho Rodrigues, Felipe Tavares Pockstaller, Mercedes Prates Nery, José Augusto da Costa |
author_role |
author |
author2 |
Quintella, Danielle Carvalho Rodrigues, Felipe Tavares Pockstaller, Mercedes Prates Nery, José Augusto da Costa |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Rodrigues, Ana Carolina Serra Quintella, Danielle Carvalho Rodrigues, Felipe Tavares Pockstaller, Mercedes Prates Nery, José Augusto da Costa |
dc.subject.por.fl_str_mv |
Leprosy Lepromatous Skin Hanseníase Virchowiana Pele |
topic |
Leprosy Lepromatous Skin Hanseníase Virchowiana Pele |
description |
Histoid leprosy, described by Wade in 1963, represents an atypical variant of lepromatous leprosy, with its own clinical and pathological features. In the past, it was considered a marker of drug resistance and relapse. It presents as keloid-like plaque or nodular lesions. Optical microscopy shows few foamy macrophages and numerous alcohol-acid-resistant bacilli and an infiltrate composed predominantly of spindle cells, which can mimic fibrohistiocytic neoplasms. We report a case of lepromatous leprosy with lesions clinically compatible with the histoid variant in order to demonstrate and reinforce the clinical polymorphism of this type of Hansen’s disease and raise awareness for the need of an early diagnosis and treatment, therefore with the interruption of the transmission chain and reduction of the occurrence of irreversible leprosy-related disability. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-03-26T00:00:00Z |
dc.type.driver.fl_str_mv |
journal article info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.29021/spdv.77.1.962 oai:ojs.revista.spdv.com.pt:article/962 |
url |
https://doi.org/10.29021/spdv.77.1.962 |
identifier_str_mv |
oai:ojs.revista.spdv.com.pt:article/962 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revista.spdv.com.pt/index.php/spdv/article/view/962 https://doi.org/10.29021/spdv.77.1.962 https://revista.spdv.com.pt/index.php/spdv/article/view/962/623 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
dc.source.none.fl_str_mv |
Journal of the Portuguese Society of Dermatology and Venereology; Vol 77 No 1 (2019): January / March; 73-76 Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 77 n. 1 (2019): Janeiro / Março; 73-76 2182-2409 2182-2395 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130567467335680 |