Infective endocarditis in intravenous drug abusers: an update

Detalhes bibliográficos
Autor(a) principal: Sousa, Cláudia
Data de Publicação: 2012
Outros Autores: Botelho, C. M., Rodrigues, Diana Alexandra Ferreira, Azeredo, Joana, Oliveira, Rosário
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/23357
Resumo: Infective endocarditis despite advances in diagnosis remains a common cause of hospitalization, with high morbidity and mortality rates. Through literature review it is possible to conclude that polymicrobial endocarditis occurs mainly in intravenous drug abusers with predominance in the right side of the heart, often with tricuspid valve involvement. This fact can be associated with the type of drug used by the patients; therefore, knowledge of the patient's history is critical for adjustment of the therapy. It is also important to emphasize that the most common combinations of organisms in polymicrobial infective endocarditis are: Staphylococcus aureus, Streptococcus pneumonia and Pseudomonas aeruginosa, as well as mixed cultures of Candida spp. and bacteria. A better understanding of the epidemiology and associated risk factors are required in order to develop an efficient therapy, although PE studies are difficult to perform due to the rarity of cases and lack of prospective cohorts.
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spelling Infective endocarditis in intravenous drug abusers: an updateInfective endocarditisBiofilmsScience & TechnologyInfective endocarditis despite advances in diagnosis remains a common cause of hospitalization, with high morbidity and mortality rates. Through literature review it is possible to conclude that polymicrobial endocarditis occurs mainly in intravenous drug abusers with predominance in the right side of the heart, often with tricuspid valve involvement. This fact can be associated with the type of drug used by the patients; therefore, knowledge of the patient's history is critical for adjustment of the therapy. It is also important to emphasize that the most common combinations of organisms in polymicrobial infective endocarditis are: Staphylococcus aureus, Streptococcus pneumonia and Pseudomonas aeruginosa, as well as mixed cultures of Candida spp. and bacteria. A better understanding of the epidemiology and associated risk factors are required in order to develop an efficient therapy, although PE studies are difficult to perform due to the rarity of cases and lack of prospective cohorts.This work was supported by Portuguese Foundation for Science and Technology (FCT) through the grants SFRH/BPD/47693/2008, SFRH/BPD/20987/2004 and SFRH/BPD/72632/2010 attributed to Claudia Sousa, Claudia Botelho and Diana Rodrigues, respectively.Springer VerlagUniversidade do MinhoSousa, CláudiaBotelho, C. M.Rodrigues, Diana Alexandra FerreiraAzeredo, JoanaOliveira, Rosário20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/23357eng0934-97231435-437310.1007/s10096-012-1675-x22714640info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:45:07Zoai:repositorium.sdum.uminho.pt:1822/23357Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:42:54.945690Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Infective endocarditis in intravenous drug abusers: an update
title Infective endocarditis in intravenous drug abusers: an update
spellingShingle Infective endocarditis in intravenous drug abusers: an update
Sousa, Cláudia
Infective endocarditis
Biofilms
Science & Technology
title_short Infective endocarditis in intravenous drug abusers: an update
title_full Infective endocarditis in intravenous drug abusers: an update
title_fullStr Infective endocarditis in intravenous drug abusers: an update
title_full_unstemmed Infective endocarditis in intravenous drug abusers: an update
title_sort Infective endocarditis in intravenous drug abusers: an update
author Sousa, Cláudia
author_facet Sousa, Cláudia
Botelho, C. M.
Rodrigues, Diana Alexandra Ferreira
Azeredo, Joana
Oliveira, Rosário
author_role author
author2 Botelho, C. M.
Rodrigues, Diana Alexandra Ferreira
Azeredo, Joana
Oliveira, Rosário
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Sousa, Cláudia
Botelho, C. M.
Rodrigues, Diana Alexandra Ferreira
Azeredo, Joana
Oliveira, Rosário
dc.subject.por.fl_str_mv Infective endocarditis
Biofilms
Science & Technology
topic Infective endocarditis
Biofilms
Science & Technology
description Infective endocarditis despite advances in diagnosis remains a common cause of hospitalization, with high morbidity and mortality rates. Through literature review it is possible to conclude that polymicrobial endocarditis occurs mainly in intravenous drug abusers with predominance in the right side of the heart, often with tricuspid valve involvement. This fact can be associated with the type of drug used by the patients; therefore, knowledge of the patient's history is critical for adjustment of the therapy. It is also important to emphasize that the most common combinations of organisms in polymicrobial infective endocarditis are: Staphylococcus aureus, Streptococcus pneumonia and Pseudomonas aeruginosa, as well as mixed cultures of Candida spp. and bacteria. A better understanding of the epidemiology and associated risk factors are required in order to develop an efficient therapy, although PE studies are difficult to perform due to the rarity of cases and lack of prospective cohorts.
publishDate 2012
dc.date.none.fl_str_mv 2012
2012-01-01T00:00:00Z
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url http://hdl.handle.net/1822/23357
dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv 0934-9723
1435-4373
10.1007/s10096-012-1675-x
22714640
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dc.publisher.none.fl_str_mv Springer Verlag
publisher.none.fl_str_mv Springer Verlag
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