Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomes

Detalhes bibliográficos
Autor(a) principal: Gomes, Filomena
Data de Publicação: 2022
Outros Autores: Agustina, Rina, Black, Robert E., Christian, Parul, Dewey, Kathryn G., Kraemer, Klaus, Shankar, Anuraj H., Smith, Emily R., Thorne-Lyman, Andrew, Tumilowicz, Alison, Bourassa, Megan W.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/141366
Resumo: Funding Information: This research was funded by a grant from the Bill & Melinda Gates Foundation (OPP1171060) to the New York Academy of Sciences. We would like to thank Sophie Moore, Shams El Arifeen, Anuraj Shankar, Sunawang Rahardjo, Zuguo Mei, and Parul Christian for responding our requests to conduct further data analyses in the studies Moore,28,29 Tofail,30 SUMMIT,20 Sunawang,21 Liu,27,38 and Christian,19 respectively, and for providing us with relevant data that had been collected but not published.
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spelling Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomesan iron dose analysisanemiaironiron deficiency anemiamicronutrient supplementspregnancyNeuroscience(all)Biochemistry, Genetics and Molecular Biology(all)History and Philosophy of ScienceFunding Information: This research was funded by a grant from the Bill & Melinda Gates Foundation (OPP1171060) to the New York Academy of Sciences. We would like to thank Sophie Moore, Shams El Arifeen, Anuraj Shankar, Sunawang Rahardjo, Zuguo Mei, and Parul Christian for responding our requests to conduct further data analyses in the studies Moore,28,29 Tofail,30 SUMMIT,20 Sunawang,21 Liu,27,38 and Christian,19 respectively, and for providing us with relevant data that had been collected but not published.Antenatal multiple micronutrient supplements (MMS) are more effective than iron and folic acid (IFA) supplements in reducing adverse pregnancy outcomes. Questions remain, however, about the ability of MMS to prevent anemia as effectively as IFA, especially at a lower dose of daily iron and in areas of high anemia prevalence. Analyzing data from 11 trials from a recent Cochrane review, we compared MMS to IFA, delivering either 30 or 60 mg of iron, in sustaining hemoglobin and preventing third trimester anemia and iron deficiency anemia (IDA), accounting for daily iron dose, total supplemental iron intake, and baseline prevalence of anemia. There were no differences between MMS and IFA in third trimester hemoglobin concentration or risks of anemia or IDA by iron dose or total supplemental iron consumed. MMS providing 30 mg of iron was comparable to IFA with 60 mg of iron: mean hemoglobin difference of −0.26 g/L (95% CI: −1.41 to 0.89), risk ratios of 0.99 (95% CI: 0.92–1.07) for anemia, and 1.31 (95% CI: 0.66–2.60) for IDA. Baseline prevalence of anemia did not explain heterogeneity in findings. Compared to IFA, MMS results in comparable hemoglobin concentration and protection against anemia during pregnancy, independently of iron dose.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNGomes, FilomenaAgustina, RinaBlack, Robert E.Christian, ParulDewey, Kathryn G.Kraemer, KlausShankar, Anuraj H.Smith, Emily R.Thorne-Lyman, AndrewTumilowicz, AlisonBourassa, Megan W.2022-07-04T22:24:02Z2022-062022-06-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article12application/pdfhttp://hdl.handle.net/10362/141366eng0077-8923PURE: 44980938https://doi.org/10.1111/nyas.14756info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:18:38Zoai:run.unl.pt:10362/141366Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:49:58.360785Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomes
an iron dose analysis
title Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomes
spellingShingle Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomes
Gomes, Filomena
anemia
iron
iron deficiency anemia
micronutrient supplements
pregnancy
Neuroscience(all)
Biochemistry, Genetics and Molecular Biology(all)
History and Philosophy of Science
title_short Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomes
title_full Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomes
title_fullStr Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomes
title_full_unstemmed Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomes
title_sort Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomes
author Gomes, Filomena
author_facet Gomes, Filomena
Agustina, Rina
Black, Robert E.
Christian, Parul
Dewey, Kathryn G.
Kraemer, Klaus
Shankar, Anuraj H.
Smith, Emily R.
Thorne-Lyman, Andrew
Tumilowicz, Alison
Bourassa, Megan W.
author_role author
author2 Agustina, Rina
Black, Robert E.
Christian, Parul
Dewey, Kathryn G.
Kraemer, Klaus
Shankar, Anuraj H.
Smith, Emily R.
Thorne-Lyman, Andrew
Tumilowicz, Alison
Bourassa, Megan W.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Gomes, Filomena
Agustina, Rina
Black, Robert E.
Christian, Parul
Dewey, Kathryn G.
Kraemer, Klaus
Shankar, Anuraj H.
Smith, Emily R.
Thorne-Lyman, Andrew
Tumilowicz, Alison
Bourassa, Megan W.
dc.subject.por.fl_str_mv anemia
iron
iron deficiency anemia
micronutrient supplements
pregnancy
Neuroscience(all)
Biochemistry, Genetics and Molecular Biology(all)
History and Philosophy of Science
topic anemia
iron
iron deficiency anemia
micronutrient supplements
pregnancy
Neuroscience(all)
Biochemistry, Genetics and Molecular Biology(all)
History and Philosophy of Science
description Funding Information: This research was funded by a grant from the Bill & Melinda Gates Foundation (OPP1171060) to the New York Academy of Sciences. We would like to thank Sophie Moore, Shams El Arifeen, Anuraj Shankar, Sunawang Rahardjo, Zuguo Mei, and Parul Christian for responding our requests to conduct further data analyses in the studies Moore,28,29 Tofail,30 SUMMIT,20 Sunawang,21 Liu,27,38 and Christian,19 respectively, and for providing us with relevant data that had been collected but not published.
publishDate 2022
dc.date.none.fl_str_mv 2022-07-04T22:24:02Z
2022-06
2022-06-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/141366
url http://hdl.handle.net/10362/141366
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0077-8923
PURE: 44980938
https://doi.org/10.1111/nyas.14756
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 12
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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