Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial Therapy in a Portuguese Hospital
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730 |
Resumo: | Introduction: Outpatient antimicrobial therapy programs have been in place for more than four decades. They provide safe and effective treatment for a selected group of patients while reducing costs. In Europe in general, and in Portugal in particular, these programs are still a relatively new phenomenon. The aim of this study is to describe our center’s two years’ experience with such a program (Antibiotic Clinic).Material and Methods: The cohort of treatments administered by the Antibiotic Clinic in its first two years of existence (September 12th 2016 to September 11th 2018) was analyzed and data pertaining to patients, infections, infectious agents, antimicrobials and outcomes (infection resolution, adverse events and death) were characterized.Results: The Antibiotic Clinic treated 231 patients in 250 episodes, providing a total of 2357 days of antibiotic treatment. The urinary tract was the most common site (39.2%) and Enterobacteriaceae the most common agents (63.7% of isolates). Infections were resolved in 90.8% of treatments (95.6% of patients), adverse events were few (1.2%) and direct mortality was not found. The dropout rate was 1.6%.Discussion: Infection resolution and adverse event rates were comparable to other centers. High treatment and low dropout rates point to high physician and patient acceptance.Conclusion: Our experience with this program suggests it is a safe and effective alternative to inpatient admission. This is in line with current literature which suggests efforts should be made to expand this treatment modality. |
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Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial Therapy in a Portuguese HospitalClínica do Antibiótico: Dois Anos de Experiência em Outpatient Parenteral Antimicrobial Therapy num Hospital PortuguêsAmbulatory CareAnti-infective AgentsAntibacterial Drug ResistanceInfection/drug therapyOutpatientsPortugalAnti-InfecciososAssistência AmbulatorialDoentes AmbulatoriaisFarmacorresistência BacterianaInfecção/tratamentoPortugalIntroduction: Outpatient antimicrobial therapy programs have been in place for more than four decades. They provide safe and effective treatment for a selected group of patients while reducing costs. In Europe in general, and in Portugal in particular, these programs are still a relatively new phenomenon. The aim of this study is to describe our center’s two years’ experience with such a program (Antibiotic Clinic).Material and Methods: The cohort of treatments administered by the Antibiotic Clinic in its first two years of existence (September 12th 2016 to September 11th 2018) was analyzed and data pertaining to patients, infections, infectious agents, antimicrobials and outcomes (infection resolution, adverse events and death) were characterized.Results: The Antibiotic Clinic treated 231 patients in 250 episodes, providing a total of 2357 days of antibiotic treatment. The urinary tract was the most common site (39.2%) and Enterobacteriaceae the most common agents (63.7% of isolates). Infections were resolved in 90.8% of treatments (95.6% of patients), adverse events were few (1.2%) and direct mortality was not found. The dropout rate was 1.6%.Discussion: Infection resolution and adverse event rates were comparable to other centers. High treatment and low dropout rates point to high physician and patient acceptance.Conclusion: Our experience with this program suggests it is a safe and effective alternative to inpatient admission. This is in line with current literature which suggests efforts should be made to expand this treatment modality.Introdução: Os programas de administração de antimicrobianos parentéricos em ambulatório (outpatient parenteral antimicrobial therapy) iniciaram-se há mais de quatro décadas. Para além de proporcionarem tratamento seguro e eficaz num grupo selecionado de doentes, permitem também a redução de custos. Na Europa, e em particular em Portugal, a implementação destes programas é um fenómeno recente. O objetivo deste estudo é descrever dois anos de experiência de Clínica do Antibiótico.Material e Métodos: Foram incluídos todos os doentes tratados na Clínica do Antibiótico nos dois primeiros anos de existência (12 de setembro de 2016 a 11 de setembro de 2018), sendo descritas variáveis relativas à população, infeções, agentes infeciosos, tratamentos e outcomes (resolução de infeção, eventos adversos e morte).Resultados: A Clínica do Antibiótico tratou 231 doentes em 250 episódios, garantindo 2357 dias de antibioterapia. O local de infeção mais comum foi o trato urinário (39,2%) e os agentes mais comuns foram as Enterobacteriaceae (63,7% dos isolamentos). Obteve-se resolução da infeção em 90,8% dos tratamentos (95,6% dos doentes), ocorreram poucos eventos adversos (1,2%) e a mortalidade direta foi nula. Houve uma taxa de abandono de 1,6%.Discussão: As taxas de resolução e de complicações foram comparáveis às de outros centros. Elevado número de tratamentos e baixa taxa de abandono apontam para boa aceitação por médicos e doentes.Conclusão: A nossa experiência sugere ser uma alternativa eficaz e segura ao tratamento em internamento. Estes resultados estão de acordo com a literatura, sugerindo que esforços deverão ser feitos para expandir a utilização destes programas.Ordem dos Médicos2019-09-02info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/mswordapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730oai:ojs.www.actamedicaportuguesa.com:article/11730Acta Médica Portuguesa; Vol. 32 No. 9 (2019): September; 576-579Acta Médica Portuguesa; Vol. 32 N.º 9 (2019): Setembro; 576-5791646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730/5753https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730/11098https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730/11249https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730/11254Direitos de Autor (c) 2019 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessRigor, JoanaFerreira, Paula MarquesMurteira, FábioFigueiredo, CristóvãoVieira, NunoOliveira, RosaCouto, RaquelMota, Margarida2022-12-20T11:06:23Zoai:ojs.www.actamedicaportuguesa.com:article/11730Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:04.733999Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial Therapy in a Portuguese Hospital Clínica do Antibiótico: Dois Anos de Experiência em Outpatient Parenteral Antimicrobial Therapy num Hospital Português |
title |
Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial Therapy in a Portuguese Hospital |
spellingShingle |
Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial Therapy in a Portuguese Hospital Rigor, Joana Ambulatory Care Anti-infective Agents Antibacterial Drug Resistance Infection/drug therapy Outpatients Portugal Anti-Infecciosos Assistência Ambulatorial Doentes Ambulatoriais Farmacorresistência Bacteriana Infecção/tratamento Portugal |
title_short |
Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial Therapy in a Portuguese Hospital |
title_full |
Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial Therapy in a Portuguese Hospital |
title_fullStr |
Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial Therapy in a Portuguese Hospital |
title_full_unstemmed |
Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial Therapy in a Portuguese Hospital |
title_sort |
Antibiotic Clinic: Two Years’ Experience in Outpatient Parenteral Antimicrobial Therapy in a Portuguese Hospital |
author |
Rigor, Joana |
author_facet |
Rigor, Joana Ferreira, Paula Marques Murteira, Fábio Figueiredo, Cristóvão Vieira, Nuno Oliveira, Rosa Couto, Raquel Mota, Margarida |
author_role |
author |
author2 |
Ferreira, Paula Marques Murteira, Fábio Figueiredo, Cristóvão Vieira, Nuno Oliveira, Rosa Couto, Raquel Mota, Margarida |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Rigor, Joana Ferreira, Paula Marques Murteira, Fábio Figueiredo, Cristóvão Vieira, Nuno Oliveira, Rosa Couto, Raquel Mota, Margarida |
dc.subject.por.fl_str_mv |
Ambulatory Care Anti-infective Agents Antibacterial Drug Resistance Infection/drug therapy Outpatients Portugal Anti-Infecciosos Assistência Ambulatorial Doentes Ambulatoriais Farmacorresistência Bacteriana Infecção/tratamento Portugal |
topic |
Ambulatory Care Anti-infective Agents Antibacterial Drug Resistance Infection/drug therapy Outpatients Portugal Anti-Infecciosos Assistência Ambulatorial Doentes Ambulatoriais Farmacorresistência Bacteriana Infecção/tratamento Portugal |
description |
Introduction: Outpatient antimicrobial therapy programs have been in place for more than four decades. They provide safe and effective treatment for a selected group of patients while reducing costs. In Europe in general, and in Portugal in particular, these programs are still a relatively new phenomenon. The aim of this study is to describe our center’s two years’ experience with such a program (Antibiotic Clinic).Material and Methods: The cohort of treatments administered by the Antibiotic Clinic in its first two years of existence (September 12th 2016 to September 11th 2018) was analyzed and data pertaining to patients, infections, infectious agents, antimicrobials and outcomes (infection resolution, adverse events and death) were characterized.Results: The Antibiotic Clinic treated 231 patients in 250 episodes, providing a total of 2357 days of antibiotic treatment. The urinary tract was the most common site (39.2%) and Enterobacteriaceae the most common agents (63.7% of isolates). Infections were resolved in 90.8% of treatments (95.6% of patients), adverse events were few (1.2%) and direct mortality was not found. The dropout rate was 1.6%.Discussion: Infection resolution and adverse event rates were comparable to other centers. High treatment and low dropout rates point to high physician and patient acceptance.Conclusion: Our experience with this program suggests it is a safe and effective alternative to inpatient admission. This is in line with current literature which suggests efforts should be made to expand this treatment modality. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-09-02 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730 oai:ojs.www.actamedicaportuguesa.com:article/11730 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/11730 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730/5753 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730/11098 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730/11249 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/11730/11254 |
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Direitos de Autor (c) 2019 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
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Direitos de Autor (c) 2019 Acta Médica Portuguesa |
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openAccess |
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application/pdf application/pdf application/msword application/pdf |
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Ordem dos Médicos |
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Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 32 No. 9 (2019): September; 576-579 Acta Médica Portuguesa; Vol. 32 N.º 9 (2019): Setembro; 576-579 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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