Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review

Detalhes bibliográficos
Autor(a) principal: Alves, Rubina
Data de Publicação: 2020
Outros Autores: Grimalt, R
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/42354
Resumo: Key Summary Points Platelet-rich plasma (PRP) is an autologous blood product containing high concentrations of platelets in a small volume of plasma. PRP may act at the dermal papilla cells to promote new hair growth, contribute to faster telogen–anagen transition, and increase hair density; good results should be expected with the use of PRP. In androgenetic alopecia, a positive effect was demonstrated after injections of PRP (mainly after three treatments), showing an increase of hair density in most patients. The results obtained with the use of PRP in alopecia areata are not so consistent. PRP might work in some types of cicatricial alopecia, such as lichen planopillaris, central centrifugal cicatricial alopecia, and frontal fibrosing alopecia.
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spelling Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative ReviewAlopeciaAlopecia areataAndrogenetic alopeciaCentral centrifugal cicatricialalopeciaCicatricial alopeciaFrontal fibrosing alopeciaNon-cicatricialalopeciaLichen planopillarisPlatelet-rich plasmaKey Summary Points Platelet-rich plasma (PRP) is an autologous blood product containing high concentrations of platelets in a small volume of plasma. PRP may act at the dermal papilla cells to promote new hair growth, contribute to faster telogen–anagen transition, and increase hair density; good results should be expected with the use of PRP. In androgenetic alopecia, a positive effect was demonstrated after injections of PRP (mainly after three treatments), showing an increase of hair density in most patients. The results obtained with the use of PRP in alopecia areata are not so consistent. PRP might work in some types of cicatricial alopecia, such as lichen planopillaris, central centrifugal cicatricial alopecia, and frontal fibrosing alopecia.The concept and description of platelet-rich plasma (PRP) started in the field of hematology and is being extensively used in other fields of medicine. Interest in the application of PRP has been increasing in dermatology, such as in tissue regeneration, wound healing, scar revision, skin-rejuvenating effects, and alopecia. PRP is an autologous blood product containing high concentrations of platelets in a small volume of plasma. Different preparations of PRP may lead to different volumes of PRP, platelet concentration, and presence or absence of leukocytes. PRP is being used as a new therapy for some types of non-cicatricial alopecia such as androgenetic alopecia (AGA) and alopecia areata (AA) and, recently, new insights refer to the possibility of action in the field of cicatricial alopecia, like lichen planopillaris (LPP) and frontal fibrosing alopecia (FFA). This article aims to identify the major indications for the application of PRP in the field of hair disorders, including non-cicatricial and cicatricial alopecia.Dermatol Ther (Heidelb)Repositório ComumAlves, RubinaGrimalt, R2022-11-21T17:47:17Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/42354eng10.1007/s13555-020-00408-5info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-10T02:19:04Zoai:comum.rcaap.pt:10400.26/42354Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:34:40.521868Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review
title Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review
spellingShingle Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review
Alves, Rubina
Alopecia
Alopecia areata
Androgenetic alopecia
Central centrifugal cicatricialalopecia
Cicatricial alopecia
Frontal fibrosing alopecia
Non-cicatricialalopecia
Lichen planopillaris
Platelet-rich plasma
title_short Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review
title_full Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review
title_fullStr Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review
title_full_unstemmed Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review
title_sort Platelet-Rich Plasma and its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review
author Alves, Rubina
author_facet Alves, Rubina
Grimalt, R
author_role author
author2 Grimalt, R
author2_role author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Alves, Rubina
Grimalt, R
dc.subject.por.fl_str_mv Alopecia
Alopecia areata
Androgenetic alopecia
Central centrifugal cicatricialalopecia
Cicatricial alopecia
Frontal fibrosing alopecia
Non-cicatricialalopecia
Lichen planopillaris
Platelet-rich plasma
topic Alopecia
Alopecia areata
Androgenetic alopecia
Central centrifugal cicatricialalopecia
Cicatricial alopecia
Frontal fibrosing alopecia
Non-cicatricialalopecia
Lichen planopillaris
Platelet-rich plasma
description Key Summary Points Platelet-rich plasma (PRP) is an autologous blood product containing high concentrations of platelets in a small volume of plasma. PRP may act at the dermal papilla cells to promote new hair growth, contribute to faster telogen–anagen transition, and increase hair density; good results should be expected with the use of PRP. In androgenetic alopecia, a positive effect was demonstrated after injections of PRP (mainly after three treatments), showing an increase of hair density in most patients. The results obtained with the use of PRP in alopecia areata are not so consistent. PRP might work in some types of cicatricial alopecia, such as lichen planopillaris, central centrifugal cicatricial alopecia, and frontal fibrosing alopecia.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
2022-11-21T17:47:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/42354
url http://hdl.handle.net/10400.26/42354
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1007/s13555-020-00408-5
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Dermatol Ther (Heidelb)
publisher.none.fl_str_mv Dermatol Ther (Heidelb)
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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