Virulence factors in coagulase-negative staphylococci

Detalhes bibliográficos
Autor(a) principal: França, Ângela Maria Oliveira Sousa
Data de Publicação: 2021
Outros Autores: Gaio, Vânia Silva, Lopes, Nathalie, Melo, Luís Daniel Rodrigues
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/70255
Resumo: Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S. lugdunensis, the most clinically relevant species. Despite being less virulent than the well-studied pathogen S. aureus, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food.
id RCAP_f3d501d749280f04a7c1e0952437f0d4
oai_identifier_str oai:repositorium.sdum.uminho.pt:1822/70255
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Virulence factors in coagulase-negative staphylococciCoagulase-negative staphylococciBiofilmsVirulence factorsScience & TechnologyCoagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S. lugdunensis, the most clinically relevant species. Despite being less virulent than the well-studied pathogen S. aureus, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food.: V.G. and N.L. acknowledge the FCT fellowship, respectively, SFRH/BD/13145/2017 and SFRH/BD/136998/2018.info:eu-repo/semantics/publishedVersionMDPIUniversidade do MinhoFrança, Ângela Maria Oliveira SousaGaio, Vânia SilvaLopes, NathalieMelo, Luís Daniel Rodrigues2021-022021-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/70255engFrança, Angela; Gaio, Vania; Lopes, N.; Melo, Luís Daniel Rodrigues, Virulence Factors in Coagulase-Negative Staphylococci. Pathogens, 10(2), 170, 20212076-081710.3390/pathogens10020170https://www.mdpi.com/2076-0817/10/2/170info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T11:56:22Zoai:repositorium.sdum.uminho.pt:1822/70255Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:45:57.792913Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Virulence factors in coagulase-negative staphylococci
title Virulence factors in coagulase-negative staphylococci
spellingShingle Virulence factors in coagulase-negative staphylococci
França, Ângela Maria Oliveira Sousa
Coagulase-negative staphylococci
Biofilms
Virulence factors
Science & Technology
title_short Virulence factors in coagulase-negative staphylococci
title_full Virulence factors in coagulase-negative staphylococci
title_fullStr Virulence factors in coagulase-negative staphylococci
title_full_unstemmed Virulence factors in coagulase-negative staphylococci
title_sort Virulence factors in coagulase-negative staphylococci
author França, Ângela Maria Oliveira Sousa
author_facet França, Ângela Maria Oliveira Sousa
Gaio, Vânia Silva
Lopes, Nathalie
Melo, Luís Daniel Rodrigues
author_role author
author2 Gaio, Vânia Silva
Lopes, Nathalie
Melo, Luís Daniel Rodrigues
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv França, Ângela Maria Oliveira Sousa
Gaio, Vânia Silva
Lopes, Nathalie
Melo, Luís Daniel Rodrigues
dc.subject.por.fl_str_mv Coagulase-negative staphylococci
Biofilms
Virulence factors
Science & Technology
topic Coagulase-negative staphylococci
Biofilms
Virulence factors
Science & Technology
description Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S. lugdunensis, the most clinically relevant species. Despite being less virulent than the well-studied pathogen S. aureus, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food.
publishDate 2021
dc.date.none.fl_str_mv 2021-02
2021-02-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/70255
url http://hdl.handle.net/1822/70255
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv França, Angela; Gaio, Vania; Lopes, N.; Melo, Luís Daniel Rodrigues, Virulence Factors in Coagulase-Negative Staphylococci. Pathogens, 10(2), 170, 2021
2076-0817
10.3390/pathogens10020170
https://www.mdpi.com/2076-0817/10/2/170
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799132214025256960

Registros relacionados