Virulence factors in coagulase-negative staphylococci
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/70255 |
Resumo: | Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S. lugdunensis, the most clinically relevant species. Despite being less virulent than the well-studied pathogen S. aureus, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food. |
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Virulence factors in coagulase-negative staphylococciCoagulase-negative staphylococciBiofilmsVirulence factorsScience & TechnologyCoagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S. lugdunensis, the most clinically relevant species. Despite being less virulent than the well-studied pathogen S. aureus, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food.: V.G. and N.L. acknowledge the FCT fellowship, respectively, SFRH/BD/13145/2017 and SFRH/BD/136998/2018.info:eu-repo/semantics/publishedVersionMDPIUniversidade do MinhoFrança, Ângela Maria Oliveira SousaGaio, Vânia SilvaLopes, NathalieMelo, Luís Daniel Rodrigues2021-022021-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/70255engFrança, Angela; Gaio, Vania; Lopes, N.; Melo, Luís Daniel Rodrigues, Virulence Factors in Coagulase-Negative Staphylococci. Pathogens, 10(2), 170, 20212076-081710.3390/pathogens10020170https://www.mdpi.com/2076-0817/10/2/170info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T11:56:22Zoai:repositorium.sdum.uminho.pt:1822/70255Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:45:57.792913Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Virulence factors in coagulase-negative staphylococci |
title |
Virulence factors in coagulase-negative staphylococci |
spellingShingle |
Virulence factors in coagulase-negative staphylococci França, Ângela Maria Oliveira Sousa Coagulase-negative staphylococci Biofilms Virulence factors Science & Technology |
title_short |
Virulence factors in coagulase-negative staphylococci |
title_full |
Virulence factors in coagulase-negative staphylococci |
title_fullStr |
Virulence factors in coagulase-negative staphylococci |
title_full_unstemmed |
Virulence factors in coagulase-negative staphylococci |
title_sort |
Virulence factors in coagulase-negative staphylococci |
author |
França, Ângela Maria Oliveira Sousa |
author_facet |
França, Ângela Maria Oliveira Sousa Gaio, Vânia Silva Lopes, Nathalie Melo, Luís Daniel Rodrigues |
author_role |
author |
author2 |
Gaio, Vânia Silva Lopes, Nathalie Melo, Luís Daniel Rodrigues |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
França, Ângela Maria Oliveira Sousa Gaio, Vânia Silva Lopes, Nathalie Melo, Luís Daniel Rodrigues |
dc.subject.por.fl_str_mv |
Coagulase-negative staphylococci Biofilms Virulence factors Science & Technology |
topic |
Coagulase-negative staphylococci Biofilms Virulence factors Science & Technology |
description |
Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S. lugdunensis, the most clinically relevant species. Despite being less virulent than the well-studied pathogen S. aureus, the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-02 2021-02-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/70255 |
url |
http://hdl.handle.net/1822/70255 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
França, Angela; Gaio, Vania; Lopes, N.; Melo, Luís Daniel Rodrigues, Virulence Factors in Coagulase-Negative Staphylococci. Pathogens, 10(2), 170, 2021 2076-0817 10.3390/pathogens10020170 https://www.mdpi.com/2076-0817/10/2/170 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799132214025256960 |