NMR spectroscopy of Group 13 metal ions : biologically relevant aspects

Detalhes bibliográficos
Autor(a) principal: André, João P.
Data de Publicação: 2003
Outros Autores: Mäcke, Helmut
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/1248
Resumo: Review
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spelling NMR spectroscopy of Group 13 metal ions : biologically relevant aspects27Al NMRBiological systemsGroup 13 elementsMRI [Magnetic Resonance Imaging]Macrocyclic complexesAl-27 NMRMRIScience & TechnologyReviewIn spite of the fact that Group 13 metal ions (Al(III), Ga(III), In(III) and Tl(I)/(III)) show no main biological role, they are NMR-active nuclides which can be used in magnetic resonance spectroscopy of biologically relevant systems. The fact that these metal ions are quadrupolar (with the exception of thallium) means that they are particularly sensitive to ligand type and coordination geometry. The line width of the NMR signals of their complexes shows a strong dependence on the symmetry of coordination, which constitutes an effective tool in the elucidation of structures. Here we report published NMR studies of this family of elements, applied to systems of biological importance. Special highlighting is given to the binding studies of these cations to biological molecules, like proteins, and to chelating agents of radiopharmaceutical interest. The possibility of in vivo NMR studies is also stressed, with extension to 27Al-based MRI (magnetic resonance imaging) experiments.ElsevierUniversidade do MinhoAndré, João P.Mäcke, Helmut20032003-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/1248eng“Journal of Inorganic Biochemistry”. 97:4 (2003) 315-323.0162-013410.1016/S0162-0134(03)00315-514568235info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:11:35Zoai:repositorium.sdum.uminho.pt:1822/1248Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:03:22.577495Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv NMR spectroscopy of Group 13 metal ions : biologically relevant aspects
title NMR spectroscopy of Group 13 metal ions : biologically relevant aspects
spellingShingle NMR spectroscopy of Group 13 metal ions : biologically relevant aspects
André, João P.
27Al NMR
Biological systems
Group 13 elements
MRI [Magnetic Resonance Imaging]
Macrocyclic complexes
Al-27 NMR
MRI
Science & Technology
title_short NMR spectroscopy of Group 13 metal ions : biologically relevant aspects
title_full NMR spectroscopy of Group 13 metal ions : biologically relevant aspects
title_fullStr NMR spectroscopy of Group 13 metal ions : biologically relevant aspects
title_full_unstemmed NMR spectroscopy of Group 13 metal ions : biologically relevant aspects
title_sort NMR spectroscopy of Group 13 metal ions : biologically relevant aspects
author André, João P.
author_facet André, João P.
Mäcke, Helmut
author_role author
author2 Mäcke, Helmut
author2_role author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv André, João P.
Mäcke, Helmut
dc.subject.por.fl_str_mv 27Al NMR
Biological systems
Group 13 elements
MRI [Magnetic Resonance Imaging]
Macrocyclic complexes
Al-27 NMR
MRI
Science & Technology
topic 27Al NMR
Biological systems
Group 13 elements
MRI [Magnetic Resonance Imaging]
Macrocyclic complexes
Al-27 NMR
MRI
Science & Technology
description Review
publishDate 2003
dc.date.none.fl_str_mv 2003
2003-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/1248
url http://hdl.handle.net/1822/1248
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv “Journal of Inorganic Biochemistry”. 97:4 (2003) 315-323.
0162-0134
10.1016/S0162-0134(03)00315-5
14568235
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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