CT-Proven Ischaemic Stroke as the First Manifestation of Occult Lung Cancer
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/3644 |
Resumo: | Cancer is associated with a higher risk of stroke, and in rare cases stroke can be the first manifestation of occult neoplasia. We present the case of a 74-year-old woman hospitalized for ischaemic stroke with multiple cerebral infarctions in several vascular territories. The exclusion of other aetiologies and the simultaneous presence of thromboembolic events in other organs raised the suspicion of a hypercoagulable state, which upon investigation revealed occult neoplasia of the lung. There was rapid deterioration, with recurrent thrombotic events despite anticoagulation, which eventually led to the patient's death. Learning points: Stroke can be the first manifestation of occult neoplasia.In the presence of cryptogenic stroke, high D-dimers, multiple brain infarctions in different vascular territories and thromboembolic events in other organs, the possibility of hidden neoplasia should be considered.Anticoagulation in disseminated intravascular coagulation is insufficient if the primary disease is not treated. |
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CT-Proven Ischaemic Stroke as the First Manifestation of Occult Lung CancerHSJ MEDStrokeLung CancerDisseminated Intravascular CoagulationCancer is associated with a higher risk of stroke, and in rare cases stroke can be the first manifestation of occult neoplasia. We present the case of a 74-year-old woman hospitalized for ischaemic stroke with multiple cerebral infarctions in several vascular territories. The exclusion of other aetiologies and the simultaneous presence of thromboembolic events in other organs raised the suspicion of a hypercoagulable state, which upon investigation revealed occult neoplasia of the lung. There was rapid deterioration, with recurrent thrombotic events despite anticoagulation, which eventually led to the patient's death. Learning points: Stroke can be the first manifestation of occult neoplasia.In the presence of cryptogenic stroke, high D-dimers, multiple brain infarctions in different vascular territories and thromboembolic events in other organs, the possibility of hidden neoplasia should be considered.Anticoagulation in disseminated intravascular coagulation is insufficient if the primary disease is not treated.Repositório do Centro Hospitalar Universitário de Lisboa Central, EPEAzeredo Costa, JRodrigues, MMonteiro, MSalvado, VDias, L2021-04-14T10:58:31Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/3644engEur J Case Rep Intern Med. 2019 Jan 18;6(1):001007.10.12890/2019_001007info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:43:52Zoai:repositorio.chlc.min-saude.pt:10400.17/3644Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:20:56.673339Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
CT-Proven Ischaemic Stroke as the First Manifestation of Occult Lung Cancer |
title |
CT-Proven Ischaemic Stroke as the First Manifestation of Occult Lung Cancer |
spellingShingle |
CT-Proven Ischaemic Stroke as the First Manifestation of Occult Lung Cancer Azeredo Costa, J HSJ MED Stroke Lung Cancer Disseminated Intravascular Coagulation |
title_short |
CT-Proven Ischaemic Stroke as the First Manifestation of Occult Lung Cancer |
title_full |
CT-Proven Ischaemic Stroke as the First Manifestation of Occult Lung Cancer |
title_fullStr |
CT-Proven Ischaemic Stroke as the First Manifestation of Occult Lung Cancer |
title_full_unstemmed |
CT-Proven Ischaemic Stroke as the First Manifestation of Occult Lung Cancer |
title_sort |
CT-Proven Ischaemic Stroke as the First Manifestation of Occult Lung Cancer |
author |
Azeredo Costa, J |
author_facet |
Azeredo Costa, J Rodrigues, M Monteiro, M Salvado, V Dias, L |
author_role |
author |
author2 |
Rodrigues, M Monteiro, M Salvado, V Dias, L |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Azeredo Costa, J Rodrigues, M Monteiro, M Salvado, V Dias, L |
dc.subject.por.fl_str_mv |
HSJ MED Stroke Lung Cancer Disseminated Intravascular Coagulation |
topic |
HSJ MED Stroke Lung Cancer Disseminated Intravascular Coagulation |
description |
Cancer is associated with a higher risk of stroke, and in rare cases stroke can be the first manifestation of occult neoplasia. We present the case of a 74-year-old woman hospitalized for ischaemic stroke with multiple cerebral infarctions in several vascular territories. The exclusion of other aetiologies and the simultaneous presence of thromboembolic events in other organs raised the suspicion of a hypercoagulable state, which upon investigation revealed occult neoplasia of the lung. There was rapid deterioration, with recurrent thrombotic events despite anticoagulation, which eventually led to the patient's death. Learning points: Stroke can be the first manifestation of occult neoplasia.In the presence of cryptogenic stroke, high D-dimers, multiple brain infarctions in different vascular territories and thromboembolic events in other organs, the possibility of hidden neoplasia should be considered.Anticoagulation in disseminated intravascular coagulation is insufficient if the primary disease is not treated. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019 2019-01-01T00:00:00Z 2021-04-14T10:58:31Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/3644 |
url |
http://hdl.handle.net/10400.17/3644 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Eur J Case Rep Intern Med. 2019 Jan 18;6(1):001007. 10.12890/2019_001007 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799131305735094272 |