Pellagra and alcoholism: case report
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng por |
Título da fonte: | Revista Ciências em Saúde |
Texto Completo: | https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292 |
Resumo: | Pellagra is mainly caused by a niacin deficiency or its precursor amino acid, tryptophan. We report a case of a male patient, 34 years old, a chronic alcoholic with delirium tremens and gastrointestinal symptoms (diarrhea, inappetence, and heartburn). He presented erythematous-brown, scaly, and well-defined plaques dispersed throughout the integument (photo-exposed areas) for 2 months that evolved with ulceration and hematic crusts. The case was diagnosed as pellagra associated with secondary bacterial infection and treated with rest, an unrestricted diet, B-complex replacement, abstention from alcohol, restriction of sun exposure, and broad-spectrum antibiotic therapy. The treatment allowed for significant improvement of symptoms in one week. Aspects of the pathophysiology and differential diagnoses of this condition are discussed, reinforcing the importance of considering pellagra in diagnosing patients with skin lesions associated with risk factors for malnutrition. |
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Pellagra and alcoholism: case reportPelagra e alcoolismo: relato de casoAlcoholismDementiaDermatitisDiarrheaPellagraAlcoolismoDemênciaDermatiteDiarreiaPelagraPellagra is mainly caused by a niacin deficiency or its precursor amino acid, tryptophan. We report a case of a male patient, 34 years old, a chronic alcoholic with delirium tremens and gastrointestinal symptoms (diarrhea, inappetence, and heartburn). He presented erythematous-brown, scaly, and well-defined plaques dispersed throughout the integument (photo-exposed areas) for 2 months that evolved with ulceration and hematic crusts. The case was diagnosed as pellagra associated with secondary bacterial infection and treated with rest, an unrestricted diet, B-complex replacement, abstention from alcohol, restriction of sun exposure, and broad-spectrum antibiotic therapy. The treatment allowed for significant improvement of symptoms in one week. Aspects of the pathophysiology and differential diagnoses of this condition are discussed, reinforcing the importance of considering pellagra in diagnosing patients with skin lesions associated with risk factors for malnutrition.Pelagra é uma doença provocada, principalmente, pela deficiência de niacina ou do seu aminoácido precursor, triptofano. Relata-se um caso de um paciente do sexo masculino, 34 anos, alcoólatra crônico com delirium tremens e sintomas gastrointestinais (diarreia, inapetência e queimação). Apresentava placas eritêmato-acastanhadas, descamativas e bem delimitadas dispersas pelo tegumento (áreas fotoexpostas) há 2 meses que evoluíram com ulceração e crostas hemáticas.O caso foi diagnosticado como pelagra associada a infecção bacteriana secundária e tratado com repouso, dieta livre, reposição do complexo B, abstenção do álcool, restrição da exposição solar e terapia antibiótica de amplo espectro. O tratamento realizado permitiu melhora significativa dos sintomas em uma semana. Aspectos da fisiopatologia e diagnósticos diferenciais dessa condição são discutidos, reforçando a importância de cogitar pelagra na hipótese diagnóstica de pacientes com lesões dermatológicas associadas a fatores de risco para desnutrição.Hospital de Clínicas de Itajubá2022-12-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer reviewedAvaliado pelos paresTextoinfo:eu-repo/semantics/otherapplication/pdfapplication/pdfhttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/129210.21876/rcshci.v12i4.1292Health Sciences Journal; v. 12 n. 4 (2022): Outubro a Dezembro de 2022; 66-70Health Sciences Journal; Vol 12 No 4 (2022): October to December 2022; 66-7010.21876/rcshci.v12i4reponame:Revista Ciências em Saúdeinstname:Hospital de Clínicas de Itajubáinstacron:HCIengporhttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292/854https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292/855Copyright (c) 2022 Health Sciences Journalhttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessNovaes, Ana Caroline Gonçalves de SáSanches, Rafael TelesSouza, João Marcos Carneiro, Zuleika Santiago de Medeiros Junior, Joanilson Andrade FreireCosta, Nilo Fernandes2024-02-13T15:54:37Zoai:ojs.portalrcs.hcitajuba.org.br:article/1292Revistahttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zeroPUBhttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/oaircs@hcitajuba.org.br||rcsfmit@medicinaitajuba.com.br2236-37852236-3785opendoar:2024-02-13T15:54:37Revista Ciências em Saúde - Hospital de Clínicas de Itajubáfalse |
dc.title.none.fl_str_mv |
Pellagra and alcoholism: case report Pelagra e alcoolismo: relato de caso |
title |
Pellagra and alcoholism: case report |
spellingShingle |
Pellagra and alcoholism: case report Novaes, Ana Caroline Gonçalves de Sá Alcoholism Dementia Dermatitis Diarrhea Pellagra Alcoolismo Demência Dermatite Diarreia Pelagra |
title_short |
Pellagra and alcoholism: case report |
title_full |
Pellagra and alcoholism: case report |
title_fullStr |
Pellagra and alcoholism: case report |
title_full_unstemmed |
Pellagra and alcoholism: case report |
title_sort |
Pellagra and alcoholism: case report |
author |
Novaes, Ana Caroline Gonçalves de Sá |
author_facet |
Novaes, Ana Caroline Gonçalves de Sá Sanches, Rafael Teles Souza, João Marcos Carneiro, Zuleika Santiago de Medeiros Junior, Joanilson Andrade Freire Costa, Nilo Fernandes |
author_role |
author |
author2 |
Sanches, Rafael Teles Souza, João Marcos Carneiro, Zuleika Santiago de Medeiros Junior, Joanilson Andrade Freire Costa, Nilo Fernandes |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Novaes, Ana Caroline Gonçalves de Sá Sanches, Rafael Teles Souza, João Marcos Carneiro, Zuleika Santiago de Medeiros Junior, Joanilson Andrade Freire Costa, Nilo Fernandes |
dc.subject.por.fl_str_mv |
Alcoholism Dementia Dermatitis Diarrhea Pellagra Alcoolismo Demência Dermatite Diarreia Pelagra |
topic |
Alcoholism Dementia Dermatitis Diarrhea Pellagra Alcoolismo Demência Dermatite Diarreia Pelagra |
description |
Pellagra is mainly caused by a niacin deficiency or its precursor amino acid, tryptophan. We report a case of a male patient, 34 years old, a chronic alcoholic with delirium tremens and gastrointestinal symptoms (diarrhea, inappetence, and heartburn). He presented erythematous-brown, scaly, and well-defined plaques dispersed throughout the integument (photo-exposed areas) for 2 months that evolved with ulceration and hematic crusts. The case was diagnosed as pellagra associated with secondary bacterial infection and treated with rest, an unrestricted diet, B-complex replacement, abstention from alcohol, restriction of sun exposure, and broad-spectrum antibiotic therapy. The treatment allowed for significant improvement of symptoms in one week. Aspects of the pathophysiology and differential diagnoses of this condition are discussed, reinforcing the importance of considering pellagra in diagnosing patients with skin lesions associated with risk factors for malnutrition. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-12-25 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer reviewed Avaliado pelos pares Texto info:eu-repo/semantics/other |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292 10.21876/rcshci.v12i4.1292 |
url |
https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292 |
identifier_str_mv |
10.21876/rcshci.v12i4.1292 |
dc.language.iso.fl_str_mv |
eng por |
language |
eng por |
dc.relation.none.fl_str_mv |
https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292/854 https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292/855 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Health Sciences Journal https://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Health Sciences Journal https://creativecommons.org/licenses/by-nc-sa/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Hospital de Clínicas de Itajubá |
publisher.none.fl_str_mv |
Hospital de Clínicas de Itajubá |
dc.source.none.fl_str_mv |
Health Sciences Journal; v. 12 n. 4 (2022): Outubro a Dezembro de 2022; 66-70 Health Sciences Journal; Vol 12 No 4 (2022): October to December 2022; 66-70 10.21876/rcshci.v12i4 reponame:Revista Ciências em Saúde instname:Hospital de Clínicas de Itajubá instacron:HCI |
instname_str |
Hospital de Clínicas de Itajubá |
instacron_str |
HCI |
institution |
HCI |
reponame_str |
Revista Ciências em Saúde |
collection |
Revista Ciências em Saúde |
repository.name.fl_str_mv |
Revista Ciências em Saúde - Hospital de Clínicas de Itajubá |
repository.mail.fl_str_mv |
rcs@hcitajuba.org.br||rcsfmit@medicinaitajuba.com.br |
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1797068960286375936 |