Pellagra and alcoholism: case report

Detalhes bibliográficos
Autor(a) principal: Novaes, Ana Caroline Gonçalves de Sá
Data de Publicação: 2022
Outros Autores: Sanches, Rafael Teles, Souza, João Marcos, Carneiro, Zuleika Santiago de Medeiros, Junior, Joanilson Andrade Freire, Costa, Nilo Fernandes
Tipo de documento: Artigo
Idioma: eng
por
Título da fonte: Revista Ciências em Saúde
Texto Completo: https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292
Resumo: Pellagra is mainly caused by a niacin deficiency or its precursor amino acid, tryptophan. We report a case of a male patient, 34 years old, a chronic alcoholic with delirium tremens and gastrointestinal symptoms (diarrhea, inappetence, and heartburn). He presented erythematous-brown, scaly, and well-defined plaques dispersed throughout the integument (photo-exposed areas) for 2 months that evolved with ulceration and hematic crusts. The case was diagnosed as pellagra associated with secondary bacterial infection and treated with rest, an unrestricted diet, B-complex replacement, abstention from alcohol, restriction of sun exposure, and broad-spectrum antibiotic therapy. The treatment allowed for significant improvement of symptoms in one week. Aspects of the pathophysiology and differential diagnoses of this condition are discussed, reinforcing the importance of considering pellagra in diagnosing patients with skin lesions associated with risk factors for malnutrition.
id RCS_58ac7d2c7817a5cc512278a75f10672d
oai_identifier_str oai:ojs.portalrcs.hcitajuba.org.br:article/1292
network_acronym_str RCS
network_name_str Revista Ciências em Saúde
repository_id_str
spelling Pellagra and alcoholism: case reportPelagra e alcoolismo: relato de casoAlcoholismDementiaDermatitisDiarrheaPellagraAlcoolismoDemênciaDermatiteDiarreiaPelagraPellagra is mainly caused by a niacin deficiency or its precursor amino acid, tryptophan. We report a case of a male patient, 34 years old, a chronic alcoholic with delirium tremens and gastrointestinal symptoms (diarrhea, inappetence, and heartburn). He presented erythematous-brown, scaly, and well-defined plaques dispersed throughout the integument (photo-exposed areas) for 2 months that evolved with ulceration and hematic crusts. The case was diagnosed as pellagra associated with secondary bacterial infection and treated with rest, an unrestricted diet, B-complex replacement, abstention from alcohol, restriction of sun exposure, and broad-spectrum antibiotic therapy. The treatment allowed for significant improvement of symptoms in one week. Aspects of the pathophysiology and differential diagnoses of this condition are discussed, reinforcing the importance of considering pellagra in diagnosing patients with skin lesions associated with risk factors for malnutrition.Pelagra é uma doença provocada, principalmente, pela deficiência de niacina ou do seu aminoácido precursor, triptofano. Relata-se um caso de um paciente do sexo masculino, 34 anos, alcoólatra crônico com delirium tremens e sintomas gastrointestinais (diarreia, inapetência e queimação). Apresentava placas eritêmato-acastanhadas, descamativas e bem delimitadas dispersas pelo tegumento (áreas fotoexpostas) há 2 meses que evoluíram com ulceração e crostas hemáticas.O caso foi diagnosticado como pelagra associada a infecção bacteriana secundária e tratado com repouso, dieta livre, reposição do complexo B, abstenção do álcool, restrição da exposição solar e terapia antibiótica de amplo espectro. O tratamento realizado permitiu melhora significativa dos sintomas em uma semana. Aspectos da fisiopatologia e diagnósticos diferenciais dessa condição são discutidos, reforçando a importância de cogitar pelagra na hipótese diagnóstica de pacientes com lesões dermatológicas associadas a fatores de risco para desnutrição.Hospital de Clínicas de Itajubá2022-12-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer reviewedAvaliado pelos paresTextoinfo:eu-repo/semantics/otherapplication/pdfapplication/pdfhttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/129210.21876/rcshci.v12i4.1292Health Sciences Journal; v. 12 n. 4 (2022): Outubro a Dezembro de 2022; 66-70Health Sciences Journal; Vol 12 No 4 (2022): October to December 2022; 66-7010.21876/rcshci.v12i4reponame:Revista Ciências em Saúdeinstname:Hospital de Clínicas de Itajubáinstacron:HCIengporhttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292/854https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292/855Copyright (c) 2022 Health Sciences Journalhttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessNovaes, Ana Caroline Gonçalves de SáSanches, Rafael TelesSouza, João Marcos Carneiro, Zuleika Santiago de Medeiros Junior, Joanilson Andrade FreireCosta, Nilo Fernandes2024-02-13T15:54:37Zoai:ojs.portalrcs.hcitajuba.org.br:article/1292Revistahttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zeroPUBhttps://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/oaircs@hcitajuba.org.br||rcsfmit@medicinaitajuba.com.br2236-37852236-3785opendoar:2024-02-13T15:54:37Revista Ciências em Saúde - Hospital de Clínicas de Itajubáfalse
dc.title.none.fl_str_mv Pellagra and alcoholism: case report
Pelagra e alcoolismo: relato de caso
title Pellagra and alcoholism: case report
spellingShingle Pellagra and alcoholism: case report
Novaes, Ana Caroline Gonçalves de Sá
Alcoholism
Dementia
Dermatitis
Diarrhea
Pellagra
Alcoolismo
Demência
Dermatite
Diarreia
Pelagra
title_short Pellagra and alcoholism: case report
title_full Pellagra and alcoholism: case report
title_fullStr Pellagra and alcoholism: case report
title_full_unstemmed Pellagra and alcoholism: case report
title_sort Pellagra and alcoholism: case report
author Novaes, Ana Caroline Gonçalves de Sá
author_facet Novaes, Ana Caroline Gonçalves de Sá
Sanches, Rafael Teles
Souza, João Marcos
Carneiro, Zuleika Santiago de Medeiros
Junior, Joanilson Andrade Freire
Costa, Nilo Fernandes
author_role author
author2 Sanches, Rafael Teles
Souza, João Marcos
Carneiro, Zuleika Santiago de Medeiros
Junior, Joanilson Andrade Freire
Costa, Nilo Fernandes
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Novaes, Ana Caroline Gonçalves de Sá
Sanches, Rafael Teles
Souza, João Marcos
Carneiro, Zuleika Santiago de Medeiros
Junior, Joanilson Andrade Freire
Costa, Nilo Fernandes
dc.subject.por.fl_str_mv Alcoholism
Dementia
Dermatitis
Diarrhea
Pellagra
Alcoolismo
Demência
Dermatite
Diarreia
Pelagra
topic Alcoholism
Dementia
Dermatitis
Diarrhea
Pellagra
Alcoolismo
Demência
Dermatite
Diarreia
Pelagra
description Pellagra is mainly caused by a niacin deficiency or its precursor amino acid, tryptophan. We report a case of a male patient, 34 years old, a chronic alcoholic with delirium tremens and gastrointestinal symptoms (diarrhea, inappetence, and heartburn). He presented erythematous-brown, scaly, and well-defined plaques dispersed throughout the integument (photo-exposed areas) for 2 months that evolved with ulceration and hematic crusts. The case was diagnosed as pellagra associated with secondary bacterial infection and treated with rest, an unrestricted diet, B-complex replacement, abstention from alcohol, restriction of sun exposure, and broad-spectrum antibiotic therapy. The treatment allowed for significant improvement of symptoms in one week. Aspects of the pathophysiology and differential diagnoses of this condition are discussed, reinforcing the importance of considering pellagra in diagnosing patients with skin lesions associated with risk factors for malnutrition.
publishDate 2022
dc.date.none.fl_str_mv 2022-12-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer reviewed
Avaliado pelos pares
Texto
info:eu-repo/semantics/other
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292
10.21876/rcshci.v12i4.1292
url https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292
identifier_str_mv 10.21876/rcshci.v12i4.1292
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292/854
https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1292/855
dc.rights.driver.fl_str_mv Copyright (c) 2022 Health Sciences Journal
https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Health Sciences Journal
https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Hospital de Clínicas de Itajubá
publisher.none.fl_str_mv Hospital de Clínicas de Itajubá
dc.source.none.fl_str_mv Health Sciences Journal; v. 12 n. 4 (2022): Outubro a Dezembro de 2022; 66-70
Health Sciences Journal; Vol 12 No 4 (2022): October to December 2022; 66-70
10.21876/rcshci.v12i4
reponame:Revista Ciências em Saúde
instname:Hospital de Clínicas de Itajubá
instacron:HCI
instname_str Hospital de Clínicas de Itajubá
instacron_str HCI
institution HCI
reponame_str Revista Ciências em Saúde
collection Revista Ciências em Saúde
repository.name.fl_str_mv Revista Ciências em Saúde - Hospital de Clínicas de Itajubá
repository.mail.fl_str_mv rcs@hcitajuba.org.br||rcsfmit@medicinaitajuba.com.br
_version_ 1797068960286375936