VIRTUAL DETERMINATION OF BLOOD GLUCOSE OBTAINED FROM FED RATS AND FROM 24-HOUR FASTED RATS
Autor(a) principal: | |
---|---|
Data de Publicação: | 2016 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista de Ensino de Bioquímica |
Texto Completo: | http://bioquimica.org.br/revista/ojs/index.php/REB/article/view/K04 |
Resumo: | INTRODUCTION: The normal blood glucose in rats is 100 mg glucose / 100 ml of blood plasma. After a 24hhour fast, a decrease around 30% of this value occurs. This reduction can reach 45% in a prolonged fast. Several processes controlled by neurohormonal mechanisms prevent a more pronounced decrease in blood glucose of animals subjected to fast. These processes are hepatic glycogenolysis, hepatic gluconeogenesis, decrease of glucose utilization and increase of fatty acids use by muscle tissue, and ketone bodies utilization by the central nervous system. OBJECTIVES: This study presents a learning object, mediated by computer, which simulates the determination of blood glucose (glycemia) obtained from fed rats and from 24-hour fasted rats. MATERIALS AND METHODS: At first, cartoons were planned in order to show the biochemical and methodology fundamentals. The most representative images were selected, edited and inserted into an animation developed with the aid of the Adobe ® Flash 8 software. DISCUSSION AND RESULTS: The animated simulation of a standard glucose curve, followed by virtual evaluation of glucose in blood plasma samples were developed, associated with some questions. This object has been used by students of Biochemistry I (Pharmacy-UFRGS) since second semester of 2009. The navigation features, design and interactivity have been evaluated as excellent by about 80% of them. CONCLUSION: Therefore, this learning object can be considered an adequate teaching resource as well as an innovative support in the construction of theoretical and practical knowledge of Biochemistry. Available at: http://www.ufrgs.br/gcoeb/dosagemglicemia/ |
id |
SBBQM-1_93c4daccd4664da4fa9926b3edbe9ead |
---|---|
oai_identifier_str |
oai:ojs.bioquimica.org.br:article/663 |
network_acronym_str |
SBBQM-1 |
network_name_str |
Revista de Ensino de Bioquímica |
repository_id_str |
|
spelling |
VIRTUAL DETERMINATION OF BLOOD GLUCOSE OBTAINED FROM FED RATS AND FROM 24-HOUR FASTED RATSglycemia; learning object; standard curve simulationINTRODUCTION: The normal blood glucose in rats is 100 mg glucose / 100 ml of blood plasma. After a 24hhour fast, a decrease around 30% of this value occurs. This reduction can reach 45% in a prolonged fast. Several processes controlled by neurohormonal mechanisms prevent a more pronounced decrease in blood glucose of animals subjected to fast. These processes are hepatic glycogenolysis, hepatic gluconeogenesis, decrease of glucose utilization and increase of fatty acids use by muscle tissue, and ketone bodies utilization by the central nervous system. OBJECTIVES: This study presents a learning object, mediated by computer, which simulates the determination of blood glucose (glycemia) obtained from fed rats and from 24-hour fasted rats. MATERIALS AND METHODS: At first, cartoons were planned in order to show the biochemical and methodology fundamentals. The most representative images were selected, edited and inserted into an animation developed with the aid of the Adobe ® Flash 8 software. DISCUSSION AND RESULTS: The animated simulation of a standard glucose curve, followed by virtual evaluation of glucose in blood plasma samples were developed, associated with some questions. This object has been used by students of Biochemistry I (Pharmacy-UFRGS) since second semester of 2009. The navigation features, design and interactivity have been evaluated as excellent by about 80% of them. CONCLUSION: Therefore, this learning object can be considered an adequate teaching resource as well as an innovative support in the construction of theoretical and practical knowledge of Biochemistry. Available at: http://www.ufrgs.br/gcoeb/dosagemglicemia/Sociedade Brasileira de Bioquímica e Biologia Molecular - SBBqTrindade, Vera Maria TreisArantes, Pablo RicardoZanatta, GeancarloSalbego, Christianne Gazzana2016-11-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionResumos SBBq - avaliados pelos paresSBBq resúmenes - revisada por paresSBBq abstracts / peer-reviewedapplication/pdfhttp://bioquimica.org.br/revista/ojs/index.php/REB/article/view/K0410.16923/reb.v14i2.663Revista de Ensino de Bioquímica; v. 14 (2016): Especial eventos; 10Revista de Enseñanza de Bioquímica; v. 14 (2016): Especial eventos; 10Journal of Biochemistry Education; v. 14 (2016): Especial eventos; 10Revista de Ensino de Bioquímica; v. 14 (2016): Especial eventos; 102318-8790reponame:Revista de Ensino de Bioquímicainstname:Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq)instacron:SBBQMenghttp://bioquimica.org.br/revista/ojs/index.php/REB/article/view/K04/550Direitos autorais 2016 Revista de Ensino de Bioquímicahttp://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccess2022-03-25T17:24:49Zoai:ojs.bioquimica.org.br:article/663Revistahttp://bioquimica.org.br/revista/ojs/index.php/REBONGhttp://bioquimica.org.br/revista/ojs/index.php/REB/oaicontato@bioquimica.org.br||ensinodebioquimica@gmail.com2318-87901677-2318opendoar:2022-03-25T17:24:49Revista de Ensino de Bioquímica - Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq)false |
dc.title.none.fl_str_mv |
VIRTUAL DETERMINATION OF BLOOD GLUCOSE OBTAINED FROM FED RATS AND FROM 24-HOUR FASTED RATS |
title |
VIRTUAL DETERMINATION OF BLOOD GLUCOSE OBTAINED FROM FED RATS AND FROM 24-HOUR FASTED RATS |
spellingShingle |
VIRTUAL DETERMINATION OF BLOOD GLUCOSE OBTAINED FROM FED RATS AND FROM 24-HOUR FASTED RATS Trindade, Vera Maria Treis glycemia; learning object; standard curve simulation |
title_short |
VIRTUAL DETERMINATION OF BLOOD GLUCOSE OBTAINED FROM FED RATS AND FROM 24-HOUR FASTED RATS |
title_full |
VIRTUAL DETERMINATION OF BLOOD GLUCOSE OBTAINED FROM FED RATS AND FROM 24-HOUR FASTED RATS |
title_fullStr |
VIRTUAL DETERMINATION OF BLOOD GLUCOSE OBTAINED FROM FED RATS AND FROM 24-HOUR FASTED RATS |
title_full_unstemmed |
VIRTUAL DETERMINATION OF BLOOD GLUCOSE OBTAINED FROM FED RATS AND FROM 24-HOUR FASTED RATS |
title_sort |
VIRTUAL DETERMINATION OF BLOOD GLUCOSE OBTAINED FROM FED RATS AND FROM 24-HOUR FASTED RATS |
author |
Trindade, Vera Maria Treis |
author_facet |
Trindade, Vera Maria Treis Arantes, Pablo Ricardo Zanatta, Geancarlo Salbego, Christianne Gazzana |
author_role |
author |
author2 |
Arantes, Pablo Ricardo Zanatta, Geancarlo Salbego, Christianne Gazzana |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
|
dc.contributor.author.fl_str_mv |
Trindade, Vera Maria Treis Arantes, Pablo Ricardo Zanatta, Geancarlo Salbego, Christianne Gazzana |
dc.subject.none.fl_str_mv |
|
dc.subject.por.fl_str_mv |
glycemia; learning object; standard curve simulation |
topic |
glycemia; learning object; standard curve simulation |
description |
INTRODUCTION: The normal blood glucose in rats is 100 mg glucose / 100 ml of blood plasma. After a 24hhour fast, a decrease around 30% of this value occurs. This reduction can reach 45% in a prolonged fast. Several processes controlled by neurohormonal mechanisms prevent a more pronounced decrease in blood glucose of animals subjected to fast. These processes are hepatic glycogenolysis, hepatic gluconeogenesis, decrease of glucose utilization and increase of fatty acids use by muscle tissue, and ketone bodies utilization by the central nervous system. OBJECTIVES: This study presents a learning object, mediated by computer, which simulates the determination of blood glucose (glycemia) obtained from fed rats and from 24-hour fasted rats. MATERIALS AND METHODS: At first, cartoons were planned in order to show the biochemical and methodology fundamentals. The most representative images were selected, edited and inserted into an animation developed with the aid of the Adobe ® Flash 8 software. DISCUSSION AND RESULTS: The animated simulation of a standard glucose curve, followed by virtual evaluation of glucose in blood plasma samples were developed, associated with some questions. This object has been used by students of Biochemistry I (Pharmacy-UFRGS) since second semester of 2009. The navigation features, design and interactivity have been evaluated as excellent by about 80% of them. CONCLUSION: Therefore, this learning object can be considered an adequate teaching resource as well as an innovative support in the construction of theoretical and practical knowledge of Biochemistry. Available at: http://www.ufrgs.br/gcoeb/dosagemglicemia/ |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-11-20 |
dc.type.none.fl_str_mv |
|
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Resumos SBBq - avaliados pelos pares SBBq resúmenes - revisada por pares SBBq abstracts / peer-reviewed |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://bioquimica.org.br/revista/ojs/index.php/REB/article/view/K04 10.16923/reb.v14i2.663 |
url |
http://bioquimica.org.br/revista/ojs/index.php/REB/article/view/K04 |
identifier_str_mv |
10.16923/reb.v14i2.663 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://bioquimica.org.br/revista/ojs/index.php/REB/article/view/K04/550 |
dc.rights.driver.fl_str_mv |
Direitos autorais 2016 Revista de Ensino de Bioquímica http://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos autorais 2016 Revista de Ensino de Bioquímica http://creativecommons.org/licenses/by-nc-sa/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.coverage.none.fl_str_mv |
|
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Bioquímica e Biologia Molecular - SBBq |
publisher.none.fl_str_mv |
Sociedade Brasileira de Bioquímica e Biologia Molecular - SBBq |
dc.source.none.fl_str_mv |
Revista de Ensino de Bioquímica; v. 14 (2016): Especial eventos; 10 Revista de Enseñanza de Bioquímica; v. 14 (2016): Especial eventos; 10 Journal of Biochemistry Education; v. 14 (2016): Especial eventos; 10 Revista de Ensino de Bioquímica; v. 14 (2016): Especial eventos; 10 2318-8790 reponame:Revista de Ensino de Bioquímica instname:Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq) instacron:SBBQM |
instname_str |
Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq) |
instacron_str |
SBBQM |
institution |
SBBQM |
reponame_str |
Revista de Ensino de Bioquímica |
collection |
Revista de Ensino de Bioquímica |
repository.name.fl_str_mv |
Revista de Ensino de Bioquímica - Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq) |
repository.mail.fl_str_mv |
contato@bioquimica.org.br||ensinodebioquimica@gmail.com |
_version_ |
1752126679128473600 |