Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos Brasileiros de Cardiologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019001000758 |
Resumo: | Abstract Coronary computed tomography angiography (CCTA) has gained a prominent role in the evaluation of coronary artery disease. However, its anatomical nature does not allow the evaluation of the functional repercussion of coronary obstructions. It has been made possible to evaluate Myocardial computed tomography perfusion (Myocardial CTP) recently, based on myocardial contrast changes related to coronary stenoses. Several studies have validated this technique against the anatomical reference method (cardiac catheterization) and other functional methods, including myocardial perfusion scintigraphy and fractional flow reserve. The Myocardial CTP is performed in conjunction with the CCTA, a combined analysis of anatomy and function. The stress phase (with assessment of myocardial perfusion) can be performed before or after the resting phase (assessment of resting perfusion and coronary arteries), and different acquisition parameters are proposed according to the protocol and type of equipment used. Stressors used are based on coronary vasodilation (e.g. dipyridamole, adenosine). Image interpretation, similar to other perfusion assessment methods, is based on the identification and quantification of myocardial perfusion defects. The integration of both perfusion and anatomical findings is fundamental for the examination interpretation algorithm, allowing to define if the stenoses identified are hemodynamically significant and may be related to myocardial ischemia. |
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Arquivos Brasileiros de Cardiologia (Online) |
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Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and RecommendationsComputed Tomography Angiography/methodsMyocardial Perfusion Imaging/methodsCoronary Artery DiseaseDipyridamoleAdenosineVasodilatationAbstract Coronary computed tomography angiography (CCTA) has gained a prominent role in the evaluation of coronary artery disease. However, its anatomical nature does not allow the evaluation of the functional repercussion of coronary obstructions. It has been made possible to evaluate Myocardial computed tomography perfusion (Myocardial CTP) recently, based on myocardial contrast changes related to coronary stenoses. Several studies have validated this technique against the anatomical reference method (cardiac catheterization) and other functional methods, including myocardial perfusion scintigraphy and fractional flow reserve. The Myocardial CTP is performed in conjunction with the CCTA, a combined analysis of anatomy and function. The stress phase (with assessment of myocardial perfusion) can be performed before or after the resting phase (assessment of resting perfusion and coronary arteries), and different acquisition parameters are proposed according to the protocol and type of equipment used. Stressors used are based on coronary vasodilation (e.g. dipyridamole, adenosine). Image interpretation, similar to other perfusion assessment methods, is based on the identification and quantification of myocardial perfusion defects. The integration of both perfusion and anatomical findings is fundamental for the examination interpretation algorithm, allowing to define if the stenoses identified are hemodynamically significant and may be related to myocardial ischemia.Sociedade Brasileira de Cardiologia - SBC2019-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019001000758Arquivos Brasileiros de Cardiologia v.113 n.4 2019reponame:Arquivos Brasileiros de Cardiologia (Online)instname:Sociedade Brasileira de Cardiologia (SBC)instacron:SBC10.5935/abc.20190217info:eu-repo/semantics/openAccessMagalhães,Tiago AugustoCury,Roberto CaldeiraCerci,Rodrigo JulioParga Filho,José RodriguesGottlieb,IlanNacif,Marcelo SoutoPinto,Ibraim MasciarelliRochitte,Carlos EduardoVilas-Boas,FabioSchvartzman,Paulo R.eng2019-10-29T00:00:00Zoai:scielo:S0066-782X2019001000758Revistahttp://www.arquivosonline.com.br/https://old.scielo.br/oai/scielo-oai.php||arquivos@cardiol.br1678-41700066-782Xopendoar:2019-10-29T00:00Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC)false |
dc.title.none.fl_str_mv |
Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title |
Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
spellingShingle |
Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations Magalhães,Tiago Augusto Computed Tomography Angiography/methods Myocardial Perfusion Imaging/methods Coronary Artery Disease Dipyridamole Adenosine Vasodilatation |
title_short |
Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title_full |
Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title_fullStr |
Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title_full_unstemmed |
Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title_sort |
Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
author |
Magalhães,Tiago Augusto |
author_facet |
Magalhães,Tiago Augusto Cury,Roberto Caldeira Cerci,Rodrigo Julio Parga Filho,José Rodrigues Gottlieb,Ilan Nacif,Marcelo Souto Pinto,Ibraim Masciarelli Rochitte,Carlos Eduardo Vilas-Boas,Fabio Schvartzman,Paulo R. |
author_role |
author |
author2 |
Cury,Roberto Caldeira Cerci,Rodrigo Julio Parga Filho,José Rodrigues Gottlieb,Ilan Nacif,Marcelo Souto Pinto,Ibraim Masciarelli Rochitte,Carlos Eduardo Vilas-Boas,Fabio Schvartzman,Paulo R. |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Magalhães,Tiago Augusto Cury,Roberto Caldeira Cerci,Rodrigo Julio Parga Filho,José Rodrigues Gottlieb,Ilan Nacif,Marcelo Souto Pinto,Ibraim Masciarelli Rochitte,Carlos Eduardo Vilas-Boas,Fabio Schvartzman,Paulo R. |
dc.subject.por.fl_str_mv |
Computed Tomography Angiography/methods Myocardial Perfusion Imaging/methods Coronary Artery Disease Dipyridamole Adenosine Vasodilatation |
topic |
Computed Tomography Angiography/methods Myocardial Perfusion Imaging/methods Coronary Artery Disease Dipyridamole Adenosine Vasodilatation |
description |
Abstract Coronary computed tomography angiography (CCTA) has gained a prominent role in the evaluation of coronary artery disease. However, its anatomical nature does not allow the evaluation of the functional repercussion of coronary obstructions. It has been made possible to evaluate Myocardial computed tomography perfusion (Myocardial CTP) recently, based on myocardial contrast changes related to coronary stenoses. Several studies have validated this technique against the anatomical reference method (cardiac catheterization) and other functional methods, including myocardial perfusion scintigraphy and fractional flow reserve. The Myocardial CTP is performed in conjunction with the CCTA, a combined analysis of anatomy and function. The stress phase (with assessment of myocardial perfusion) can be performed before or after the resting phase (assessment of resting perfusion and coronary arteries), and different acquisition parameters are proposed according to the protocol and type of equipment used. Stressors used are based on coronary vasodilation (e.g. dipyridamole, adenosine). Image interpretation, similar to other perfusion assessment methods, is based on the identification and quantification of myocardial perfusion defects. The integration of both perfusion and anatomical findings is fundamental for the examination interpretation algorithm, allowing to define if the stenoses identified are hemodynamically significant and may be related to myocardial ischemia. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019001000758 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019001000758 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/abc.20190217 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia - SBC |
dc.source.none.fl_str_mv |
Arquivos Brasileiros de Cardiologia v.113 n.4 2019 reponame:Arquivos Brasileiros de Cardiologia (Online) instname:Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
instname_str |
Sociedade Brasileira de Cardiologia (SBC) |
instacron_str |
SBC |
institution |
SBC |
reponame_str |
Arquivos Brasileiros de Cardiologia (Online) |
collection |
Arquivos Brasileiros de Cardiologia (Online) |
repository.name.fl_str_mv |
Arquivos Brasileiros de Cardiologia (Online) - Sociedade Brasileira de Cardiologia (SBC) |
repository.mail.fl_str_mv |
||arquivos@cardiol.br |
_version_ |
1752126569663430656 |