Absence of arteriosclerosis in intramyocardial coronary arteries: a mystery to be solved?
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Brazilian Journal of Cardiovascular Surgery (Online) |
| Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382011000300020 |
Resumo: | Several studies show that portions of intramyocardial coronary arteries are spared of arteriosclerosis, involving morphological, embryological, biochemical and pathophysiological aspects. Endothelial function is significantly affected in the segment of transition, as estimated by the vasoactive response to Ach. These findings suggest that myocardial bridge can provide protection against arteriosclerosis by counteracting the negative effects of endothelial dysfunction. The intramyocardial portion's protection phenomenon deserves further scientific research on all research fronts. Improved morphological, biomechanical and especially physiological and embryological knowledge may be the key to a future window of opportunity for chronic arterial disease therapy and prevention. In addition, this review discusses possible therapeutic approaches for symptomatic coronary ischemia caused by myocardial bridges |
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Absence of arteriosclerosis in intramyocardial coronary arteries: a mystery to be solved?Myocardial bridgingCoronary circulationEndotheliumSeveral studies show that portions of intramyocardial coronary arteries are spared of arteriosclerosis, involving morphological, embryological, biochemical and pathophysiological aspects. Endothelial function is significantly affected in the segment of transition, as estimated by the vasoactive response to Ach. These findings suggest that myocardial bridge can provide protection against arteriosclerosis by counteracting the negative effects of endothelial dysfunction. The intramyocardial portion's protection phenomenon deserves further scientific research on all research fronts. Improved morphological, biomechanical and especially physiological and embryological knowledge may be the key to a future window of opportunity for chronic arterial disease therapy and prevention. In addition, this review discusses possible therapeutic approaches for symptomatic coronary ischemia caused by myocardial bridgesSociedade Brasileira de Cirurgia Cardiovascular2011-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382011000300020Brazilian Journal of Cardiovascular Surgery v.26 n.3 2011reponame:Brazilian Journal of Cardiovascular Surgery (Online)instname:Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)instacron:SBCCV10.5935/1678-9741.20110020info:eu-repo/semantics/openAccessRamalli Jr,Edvaldo LuizBraga,Leonardo HenriqueEvora,Patricia MartinezAlbuquerque,Agnes Afrodite SumarelliCelotto,Andrea CarlaMota,André LuppEvora,Paulo Roberto Barbosaeng2011-12-15T00:00:00Zoai:scielo:S0102-76382011000300020Revistahttp://www.rbccv.org.br/https://old.scielo.br/oai/scielo-oai.php||rosangela.monteiro@incor.usp.br|| domingo@braile.com.br|| brandau@braile.com.br1678-97410102-7638opendoar:2011-12-15T00:00Brazilian Journal of Cardiovascular Surgery (Online) - Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)false |
| dc.title.none.fl_str_mv |
Absence of arteriosclerosis in intramyocardial coronary arteries: a mystery to be solved? |
| title |
Absence of arteriosclerosis in intramyocardial coronary arteries: a mystery to be solved? |
| spellingShingle |
Absence of arteriosclerosis in intramyocardial coronary arteries: a mystery to be solved? Ramalli Jr,Edvaldo Luiz Myocardial bridging Coronary circulation Endothelium |
| title_short |
Absence of arteriosclerosis in intramyocardial coronary arteries: a mystery to be solved? |
| title_full |
Absence of arteriosclerosis in intramyocardial coronary arteries: a mystery to be solved? |
| title_fullStr |
Absence of arteriosclerosis in intramyocardial coronary arteries: a mystery to be solved? |
| title_full_unstemmed |
Absence of arteriosclerosis in intramyocardial coronary arteries: a mystery to be solved? |
| title_sort |
Absence of arteriosclerosis in intramyocardial coronary arteries: a mystery to be solved? |
| author |
Ramalli Jr,Edvaldo Luiz |
| author_facet |
Ramalli Jr,Edvaldo Luiz Braga,Leonardo Henrique Evora,Patricia Martinez Albuquerque,Agnes Afrodite Sumarelli Celotto,Andrea Carla Mota,André Lupp Evora,Paulo Roberto Barbosa |
| author_role |
author |
| author2 |
Braga,Leonardo Henrique Evora,Patricia Martinez Albuquerque,Agnes Afrodite Sumarelli Celotto,Andrea Carla Mota,André Lupp Evora,Paulo Roberto Barbosa |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Ramalli Jr,Edvaldo Luiz Braga,Leonardo Henrique Evora,Patricia Martinez Albuquerque,Agnes Afrodite Sumarelli Celotto,Andrea Carla Mota,André Lupp Evora,Paulo Roberto Barbosa |
| dc.subject.por.fl_str_mv |
Myocardial bridging Coronary circulation Endothelium |
| topic |
Myocardial bridging Coronary circulation Endothelium |
| description |
Several studies show that portions of intramyocardial coronary arteries are spared of arteriosclerosis, involving morphological, embryological, biochemical and pathophysiological aspects. Endothelial function is significantly affected in the segment of transition, as estimated by the vasoactive response to Ach. These findings suggest that myocardial bridge can provide protection against arteriosclerosis by counteracting the negative effects of endothelial dysfunction. The intramyocardial portion's protection phenomenon deserves further scientific research on all research fronts. Improved morphological, biomechanical and especially physiological and embryological knowledge may be the key to a future window of opportunity for chronic arterial disease therapy and prevention. In addition, this review discusses possible therapeutic approaches for symptomatic coronary ischemia caused by myocardial bridges |
| publishDate |
2011 |
| dc.date.none.fl_str_mv |
2011-09-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382011000300020 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382011000300020 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
10.5935/1678-9741.20110020 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
text/html |
| dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cirurgia Cardiovascular |
| publisher.none.fl_str_mv |
Sociedade Brasileira de Cirurgia Cardiovascular |
| dc.source.none.fl_str_mv |
Brazilian Journal of Cardiovascular Surgery v.26 n.3 2011 reponame:Brazilian Journal of Cardiovascular Surgery (Online) instname:Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) instacron:SBCCV |
| instname_str |
Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) |
| instacron_str |
SBCCV |
| institution |
SBCCV |
| reponame_str |
Brazilian Journal of Cardiovascular Surgery (Online) |
| collection |
Brazilian Journal of Cardiovascular Surgery (Online) |
| repository.name.fl_str_mv |
Brazilian Journal of Cardiovascular Surgery (Online) - Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) |
| repository.mail.fl_str_mv |
||rosangela.monteiro@incor.usp.br|| domingo@braile.com.br|| brandau@braile.com.br |
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1752126597615321088 |