Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test

Detalhes bibliográficos
Autor(a) principal: Saraceni,Ana Flávia
Data de Publicação: 2019
Outros Autores: Azevedo,Rodrigo, Almeida,Clarissa Maria Gomes, Baraviera,Antônio Carlos, Kiss,Desiderio Roberto, Almeida,Maristela Gomes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of Coloproctology (Rio de Janeiro. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632019000200121
Resumo: ABSTRACT Globally, colorectal cancer is the third leading cause of cancer death among men and the second among women, corresponding to about 10% of all cancers. The Brazilian Ministry of Health and National Cancer Institute recommend the screening of colorectal cancer for people over 50 years-old with Fecal Occult Blood Test. Endoscopy is limited to patients with positive screening results. The aim of this study is to evaluate the incidence of malignant or premalignant lesions diagnosed by endoscopy in patients with positive or negative Fecal Occult Blood Test and assess the efficacy of Fecal Occult Blood Test to predict the finding of a malignant colorectal lesion. We carried out a cross-sectional study among patients with a Fecal Occult Blood Test result that were submitted to colonoscopy, in the same hospital, from March 2016 to July 2017. Sensitivity, specificity, positive and negative predictive value of Fecal Occult Blood Test compared to colonoscopy neoplastic findings was calculated. The total of 92 patients were enrolled, 52 (56.5%) were female, Fecal Occult Blood Test was positive in 42.4% of them and in 41 (44.6%) the colonoscopy showed abnormal findings. Polyps were the most frequent alteration, found in 20 patients (21.7%). Among the patients with polyps, 15 (16.3%) had neoplastic and 5 (5.4%) presented non-neoplastic polyps. The Fecal Occult Blood Test sensitivity for detection of neoplastic polyps was 66.7%, specificity 62.3%, positive predictive value 11% and negative predictive value was 94.2%. Considering the need for a screening method, Fecal Occult Blood Test showed to be an effective and reliable screening test that can be applied in public health programs to detect and prevent colorectal cancer.
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spelling Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening testColonoscopyFecal occult blood testPolypsAdenomaAdenocarcinomaABSTRACT Globally, colorectal cancer is the third leading cause of cancer death among men and the second among women, corresponding to about 10% of all cancers. The Brazilian Ministry of Health and National Cancer Institute recommend the screening of colorectal cancer for people over 50 years-old with Fecal Occult Blood Test. Endoscopy is limited to patients with positive screening results. The aim of this study is to evaluate the incidence of malignant or premalignant lesions diagnosed by endoscopy in patients with positive or negative Fecal Occult Blood Test and assess the efficacy of Fecal Occult Blood Test to predict the finding of a malignant colorectal lesion. We carried out a cross-sectional study among patients with a Fecal Occult Blood Test result that were submitted to colonoscopy, in the same hospital, from March 2016 to July 2017. Sensitivity, specificity, positive and negative predictive value of Fecal Occult Blood Test compared to colonoscopy neoplastic findings was calculated. The total of 92 patients were enrolled, 52 (56.5%) were female, Fecal Occult Blood Test was positive in 42.4% of them and in 41 (44.6%) the colonoscopy showed abnormal findings. Polyps were the most frequent alteration, found in 20 patients (21.7%). Among the patients with polyps, 15 (16.3%) had neoplastic and 5 (5.4%) presented non-neoplastic polyps. The Fecal Occult Blood Test sensitivity for detection of neoplastic polyps was 66.7%, specificity 62.3%, positive predictive value 11% and negative predictive value was 94.2%. Considering the need for a screening method, Fecal Occult Blood Test showed to be an effective and reliable screening test that can be applied in public health programs to detect and prevent colorectal cancer.Sociedade Brasileira de Coloproctologia2019-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632019000200121Journal of Coloproctology (Rio de Janeiro) v.39 n.2 2019reponame:Journal of Coloproctology (Rio de Janeiro. Online)instname:Sociedade Brasileira de Coloproctologia (SBCP)instacron:SBCP10.1016/j.jcol.2018.10.011info:eu-repo/semantics/openAccessSaraceni,Ana FláviaAzevedo,RodrigoAlmeida,Clarissa Maria GomesBaraviera,Antônio CarlosKiss,Desiderio RobertoAlmeida,Maristela Gomeseng2019-06-10T00:00:00Zoai:scielo:S2237-93632019000200121Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-9363&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||sbcp@sbcp.org.br2317-64232237-9363opendoar:2019-06-10T00:00Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)false
dc.title.none.fl_str_mv Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test
title Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test
spellingShingle Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test
Saraceni,Ana Flávia
Colonoscopy
Fecal occult blood test
Polyps
Adenoma
Adenocarcinoma
title_short Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test
title_full Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test
title_fullStr Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test
title_full_unstemmed Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test
title_sort Association of fecal occult blood tests results with colonoscopic findings in a general hospital and validation of the screening test
author Saraceni,Ana Flávia
author_facet Saraceni,Ana Flávia
Azevedo,Rodrigo
Almeida,Clarissa Maria Gomes
Baraviera,Antônio Carlos
Kiss,Desiderio Roberto
Almeida,Maristela Gomes
author_role author
author2 Azevedo,Rodrigo
Almeida,Clarissa Maria Gomes
Baraviera,Antônio Carlos
Kiss,Desiderio Roberto
Almeida,Maristela Gomes
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Saraceni,Ana Flávia
Azevedo,Rodrigo
Almeida,Clarissa Maria Gomes
Baraviera,Antônio Carlos
Kiss,Desiderio Roberto
Almeida,Maristela Gomes
dc.subject.por.fl_str_mv Colonoscopy
Fecal occult blood test
Polyps
Adenoma
Adenocarcinoma
topic Colonoscopy
Fecal occult blood test
Polyps
Adenoma
Adenocarcinoma
description ABSTRACT Globally, colorectal cancer is the third leading cause of cancer death among men and the second among women, corresponding to about 10% of all cancers. The Brazilian Ministry of Health and National Cancer Institute recommend the screening of colorectal cancer for people over 50 years-old with Fecal Occult Blood Test. Endoscopy is limited to patients with positive screening results. The aim of this study is to evaluate the incidence of malignant or premalignant lesions diagnosed by endoscopy in patients with positive or negative Fecal Occult Blood Test and assess the efficacy of Fecal Occult Blood Test to predict the finding of a malignant colorectal lesion. We carried out a cross-sectional study among patients with a Fecal Occult Blood Test result that were submitted to colonoscopy, in the same hospital, from March 2016 to July 2017. Sensitivity, specificity, positive and negative predictive value of Fecal Occult Blood Test compared to colonoscopy neoplastic findings was calculated. The total of 92 patients were enrolled, 52 (56.5%) were female, Fecal Occult Blood Test was positive in 42.4% of them and in 41 (44.6%) the colonoscopy showed abnormal findings. Polyps were the most frequent alteration, found in 20 patients (21.7%). Among the patients with polyps, 15 (16.3%) had neoplastic and 5 (5.4%) presented non-neoplastic polyps. The Fecal Occult Blood Test sensitivity for detection of neoplastic polyps was 66.7%, specificity 62.3%, positive predictive value 11% and negative predictive value was 94.2%. Considering the need for a screening method, Fecal Occult Blood Test showed to be an effective and reliable screening test that can be applied in public health programs to detect and prevent colorectal cancer.
publishDate 2019
dc.date.none.fl_str_mv 2019-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632019000200121
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632019000200121
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.jcol.2018.10.011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
dc.source.none.fl_str_mv Journal of Coloproctology (Rio de Janeiro) v.39 n.2 2019
reponame:Journal of Coloproctology (Rio de Janeiro. Online)
instname:Sociedade Brasileira de Coloproctologia (SBCP)
instacron:SBCP
instname_str Sociedade Brasileira de Coloproctologia (SBCP)
instacron_str SBCP
institution SBCP
reponame_str Journal of Coloproctology (Rio de Janeiro. Online)
collection Journal of Coloproctology (Rio de Janeiro. Online)
repository.name.fl_str_mv Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)
repository.mail.fl_str_mv ||sbcp@sbcp.org.br
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