Colorectal cancer screening

Detalhes bibliográficos
Autor(a) principal: Almeida,Frederico Ferreira Novaes de
Data de Publicação: 2000
Outros Autores: Araujo,Sérgio Eduardo Alonso, Santos,Fábio Pires de Souza, Franco,Cláudio José Castro da Silva, Santos,Vinicius Rocha, Nahas,Sergio Carlos, Habr-Gama,Angelita
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Hospital das Clínicas
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812000000100007
Resumo: Colorectal cancer (CRC) is the third most common cancer in the world, and mortality has remained the same for the past 50 years, despite advances in diagnosis and treatment. Because significant numbers of patients present with advanced or incurable stages, patients with pre-malignant lesions (adenomatous polyps) that occur as result of genetic inheritance or age should be screened, and patients with long-standing inflammatory bowel disease should undergo surveillance. There are different risk groups for CRC, as well as different screening strategies. It remains to be determined which screening protocol is the most cost-effective for each risk catagory. The objective of screening is to reduce morbidity and mortality in a target population. The purpose of this review is to analyze the results of the published CRC screening studies, with regard to the measured reduction of morbidity and mortality, due to CRC in the studied populations, following various screening procedures. The main screening techniques, used in combination or alone, include fecal occult blood tests, flexible sigmoidoscopy, and colonoscopy. Evidence from the published literature on screening methods for specific risk groups is scanty and frequently does not arise from controlled studies. Nevertheless, data from these studies, combined with recent advances in molecular genetics, certainly lead the way to greater efficacy and lower cost of CRC screening.
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spelling Colorectal cancer screeningColorectal cancerScreeningSigmoidoscopyColonoscopyFecal occult blood testingColorectal cancer (CRC) is the third most common cancer in the world, and mortality has remained the same for the past 50 years, despite advances in diagnosis and treatment. Because significant numbers of patients present with advanced or incurable stages, patients with pre-malignant lesions (adenomatous polyps) that occur as result of genetic inheritance or age should be screened, and patients with long-standing inflammatory bowel disease should undergo surveillance. There are different risk groups for CRC, as well as different screening strategies. It remains to be determined which screening protocol is the most cost-effective for each risk catagory. The objective of screening is to reduce morbidity and mortality in a target population. The purpose of this review is to analyze the results of the published CRC screening studies, with regard to the measured reduction of morbidity and mortality, due to CRC in the studied populations, following various screening procedures. The main screening techniques, used in combination or alone, include fecal occult blood tests, flexible sigmoidoscopy, and colonoscopy. Evidence from the published literature on screening methods for specific risk groups is scanty and frequently does not arise from controlled studies. Nevertheless, data from these studies, combined with recent advances in molecular genetics, certainly lead the way to greater efficacy and lower cost of CRC screening.Faculdade de Medicina / Universidade de São Paulo - FM/USP2000-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812000000100007Revista do Hospital das Clínicas v.55 n.1 2000reponame:Revista do Hospital das Clínicasinstname:Universidade de São Paulo (USP)instacron:USP10.1590/S0041-87812000000100007info:eu-repo/semantics/openAccessAlmeida,Frederico Ferreira Novaes deAraujo,Sérgio Eduardo AlonsoSantos,Fábio Pires de SouzaFranco,Cláudio José Castro da SilvaSantos,Vinicius RochaNahas,Sergio CarlosHabr-Gama,Angelitaeng2000-08-24T00:00:00Zoai:scielo:S0041-87812000000100007Revistahttp://www.scielo.br/rhcPUBhttps://old.scielo.br/oai/scielo-oai.php||revista.hc@hcnet.usp.br1678-99030041-8781opendoar:2000-08-24T00:00Revista do Hospital das Clínicas - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Colorectal cancer screening
title Colorectal cancer screening
spellingShingle Colorectal cancer screening
Almeida,Frederico Ferreira Novaes de
Colorectal cancer
Screening
Sigmoidoscopy
Colonoscopy
Fecal occult blood testing
title_short Colorectal cancer screening
title_full Colorectal cancer screening
title_fullStr Colorectal cancer screening
title_full_unstemmed Colorectal cancer screening
title_sort Colorectal cancer screening
author Almeida,Frederico Ferreira Novaes de
author_facet Almeida,Frederico Ferreira Novaes de
Araujo,Sérgio Eduardo Alonso
Santos,Fábio Pires de Souza
Franco,Cláudio José Castro da Silva
Santos,Vinicius Rocha
Nahas,Sergio Carlos
Habr-Gama,Angelita
author_role author
author2 Araujo,Sérgio Eduardo Alonso
Santos,Fábio Pires de Souza
Franco,Cláudio José Castro da Silva
Santos,Vinicius Rocha
Nahas,Sergio Carlos
Habr-Gama,Angelita
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Almeida,Frederico Ferreira Novaes de
Araujo,Sérgio Eduardo Alonso
Santos,Fábio Pires de Souza
Franco,Cláudio José Castro da Silva
Santos,Vinicius Rocha
Nahas,Sergio Carlos
Habr-Gama,Angelita
dc.subject.por.fl_str_mv Colorectal cancer
Screening
Sigmoidoscopy
Colonoscopy
Fecal occult blood testing
topic Colorectal cancer
Screening
Sigmoidoscopy
Colonoscopy
Fecal occult blood testing
description Colorectal cancer (CRC) is the third most common cancer in the world, and mortality has remained the same for the past 50 years, despite advances in diagnosis and treatment. Because significant numbers of patients present with advanced or incurable stages, patients with pre-malignant lesions (adenomatous polyps) that occur as result of genetic inheritance or age should be screened, and patients with long-standing inflammatory bowel disease should undergo surveillance. There are different risk groups for CRC, as well as different screening strategies. It remains to be determined which screening protocol is the most cost-effective for each risk catagory. The objective of screening is to reduce morbidity and mortality in a target population. The purpose of this review is to analyze the results of the published CRC screening studies, with regard to the measured reduction of morbidity and mortality, due to CRC in the studied populations, following various screening procedures. The main screening techniques, used in combination or alone, include fecal occult blood tests, flexible sigmoidoscopy, and colonoscopy. Evidence from the published literature on screening methods for specific risk groups is scanty and frequently does not arise from controlled studies. Nevertheless, data from these studies, combined with recent advances in molecular genetics, certainly lead the way to greater efficacy and lower cost of CRC screening.
publishDate 2000
dc.date.none.fl_str_mv 2000-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812000000100007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812000000100007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0041-87812000000100007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade de Medicina / Universidade de São Paulo - FM/USP
publisher.none.fl_str_mv Faculdade de Medicina / Universidade de São Paulo - FM/USP
dc.source.none.fl_str_mv Revista do Hospital das Clínicas v.55 n.1 2000
reponame:Revista do Hospital das Clínicas
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista do Hospital das Clínicas
collection Revista do Hospital das Clínicas
repository.name.fl_str_mv Revista do Hospital das Clínicas - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||revista.hc@hcnet.usp.br
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