A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMIS

Detalhes bibliográficos
Autor(a) principal: Balu,Jagan
Data de Publicação: 2020
Outros Autores: Subramanian,Sankar, Suresh,P, Narayanan,AP Shankar, Sandhu,Amamndeep Sing
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Journal of Coloproctology (Rio de Janeiro. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632020000100089
Resumo: Abstract Here we describe an infrequent case of gastrointestinal stromal tumor of the rectum in a 57 year-old man with spindle cell neoplasm probably gastrointestinal stromal tumor and CT scan showed tumor from the anterior rectal wall and offered abdominoperineal resection for the same. The patient was started on imatinib and had a significant reduction in symptoms. The patient was reassessed with the CT scan, which showed a reduction in tumor size and Transanal minimally invasive surgery was planned for the patient. Use of imatinib prior to surgical resection to attain the reduced size of the tumor within the limit of resection is an attractive approach. Since tumor development can happen rapidly again after substantial tumor shrinkage, the best time to operate depending on resectability and the maximum therapeutic outcome remains divisive.
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spelling A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMISRectal gastrointestinal stromal tumorNeoadjuvant imatinibTAMISAbstract Here we describe an infrequent case of gastrointestinal stromal tumor of the rectum in a 57 year-old man with spindle cell neoplasm probably gastrointestinal stromal tumor and CT scan showed tumor from the anterior rectal wall and offered abdominoperineal resection for the same. The patient was started on imatinib and had a significant reduction in symptoms. The patient was reassessed with the CT scan, which showed a reduction in tumor size and Transanal minimally invasive surgery was planned for the patient. Use of imatinib prior to surgical resection to attain the reduced size of the tumor within the limit of resection is an attractive approach. Since tumor development can happen rapidly again after substantial tumor shrinkage, the best time to operate depending on resectability and the maximum therapeutic outcome remains divisive.Sociedade Brasileira de Coloproctologia2020-03-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632020000100089Journal of Coloproctology (Rio de Janeiro) v.40 n.1 2020reponame:Journal of Coloproctology (Rio de Janeiro. Online)instname:Sociedade Brasileira de Coloproctologia (SBCP)instacron:SBCP10.1016/j.jcol.2019.07.003info:eu-repo/semantics/openAccessBalu,JaganSubramanian,SankarSuresh,PNarayanan,AP ShankarSandhu,Amamndeep Singeng2020-03-19T00:00:00Zoai:scielo:S2237-93632020000100089Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-9363&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||sbcp@sbcp.org.br2317-64232237-9363opendoar:2020-03-19T00:00Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)false
dc.title.none.fl_str_mv A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMIS
title A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMIS
spellingShingle A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMIS
Balu,Jagan
Rectal gastrointestinal stromal tumor
Neoadjuvant imatinib
TAMIS
title_short A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMIS
title_full A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMIS
title_fullStr A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMIS
title_full_unstemmed A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMIS
title_sort A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMIS
author Balu,Jagan
author_facet Balu,Jagan
Subramanian,Sankar
Suresh,P
Narayanan,AP Shankar
Sandhu,Amamndeep Sing
author_role author
author2 Subramanian,Sankar
Suresh,P
Narayanan,AP Shankar
Sandhu,Amamndeep Sing
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Balu,Jagan
Subramanian,Sankar
Suresh,P
Narayanan,AP Shankar
Sandhu,Amamndeep Sing
dc.subject.por.fl_str_mv Rectal gastrointestinal stromal tumor
Neoadjuvant imatinib
TAMIS
topic Rectal gastrointestinal stromal tumor
Neoadjuvant imatinib
TAMIS
description Abstract Here we describe an infrequent case of gastrointestinal stromal tumor of the rectum in a 57 year-old man with spindle cell neoplasm probably gastrointestinal stromal tumor and CT scan showed tumor from the anterior rectal wall and offered abdominoperineal resection for the same. The patient was started on imatinib and had a significant reduction in symptoms. The patient was reassessed with the CT scan, which showed a reduction in tumor size and Transanal minimally invasive surgery was planned for the patient. Use of imatinib prior to surgical resection to attain the reduced size of the tumor within the limit of resection is an attractive approach. Since tumor development can happen rapidly again after substantial tumor shrinkage, the best time to operate depending on resectability and the maximum therapeutic outcome remains divisive.
publishDate 2020
dc.date.none.fl_str_mv 2020-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632020000100089
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632020000100089
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.jcol.2019.07.003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
dc.source.none.fl_str_mv Journal of Coloproctology (Rio de Janeiro) v.40 n.1 2020
reponame:Journal of Coloproctology (Rio de Janeiro. Online)
instname:Sociedade Brasileira de Coloproctologia (SBCP)
instacron:SBCP
instname_str Sociedade Brasileira de Coloproctologia (SBCP)
instacron_str SBCP
institution SBCP
reponame_str Journal of Coloproctology (Rio de Janeiro. Online)
collection Journal of Coloproctology (Rio de Janeiro. Online)
repository.name.fl_str_mv Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)
repository.mail.fl_str_mv ||sbcp@sbcp.org.br
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