Advances in research of TGF-Β1 in human testis
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Food Science and Technology (Campinas) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000102020 |
Resumo: | Abstract Transforming growth factor β1 (TGF-β1) is a polypeptide growth factor with various biological activities. Recent studies have shown that this growth factor and they receptors are expressed in human Leydig cells, Sertoli cells, spermatogonia, spermatocytes and sperm cells after birth, and are involved in the endocrine regulation of spermatogenesis. However, there is no report on the expression of TGF-β in human embryonic testis. TGF-β1 is a peptide growth factor widely distributed in germ cells at various levels in the testis, regulating the function of the testes and maintaining the stability of the testis environment by acting on various cells. This review summarizes the research progress of TGF-β1 in human testis. |
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Advances in research of TGF-Β1 in human testistransforming growth factor β1TGF-β1testicular genesisbiological functionspolypeptide growthAbstract Transforming growth factor β1 (TGF-β1) is a polypeptide growth factor with various biological activities. Recent studies have shown that this growth factor and they receptors are expressed in human Leydig cells, Sertoli cells, spermatogonia, spermatocytes and sperm cells after birth, and are involved in the endocrine regulation of spermatogenesis. However, there is no report on the expression of TGF-β in human embryonic testis. TGF-β1 is a peptide growth factor widely distributed in germ cells at various levels in the testis, regulating the function of the testes and maintaining the stability of the testis environment by acting on various cells. This review summarizes the research progress of TGF-β1 in human testis.Sociedade Brasileira de Ciência e Tecnologia de Alimentos2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000102020Food Science and Technology v.42 2022reponame:Food Science and Technology (Campinas)instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)instacron:SBCTA10.1590/fst.22521info:eu-repo/semantics/openAccessWANG,TingtingZHANG,DanSONG,TaoSUN,MengdiZHANG,Jidongeng2022-02-22T00:00:00Zoai:scielo:S0101-20612022000102020Revistahttp://www.scielo.br/ctaONGhttps://old.scielo.br/oai/scielo-oai.php||revista@sbcta.org.br1678-457X0101-2061opendoar:2022-02-22T00:00Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)false |
dc.title.none.fl_str_mv |
Advances in research of TGF-Β1 in human testis |
title |
Advances in research of TGF-Β1 in human testis |
spellingShingle |
Advances in research of TGF-Β1 in human testis WANG,Tingting transforming growth factor β1 TGF-β1 testicular genesis biological functions polypeptide growth |
title_short |
Advances in research of TGF-Β1 in human testis |
title_full |
Advances in research of TGF-Β1 in human testis |
title_fullStr |
Advances in research of TGF-Β1 in human testis |
title_full_unstemmed |
Advances in research of TGF-Β1 in human testis |
title_sort |
Advances in research of TGF-Β1 in human testis |
author |
WANG,Tingting |
author_facet |
WANG,Tingting ZHANG,Dan SONG,Tao SUN,Mengdi ZHANG,Jidong |
author_role |
author |
author2 |
ZHANG,Dan SONG,Tao SUN,Mengdi ZHANG,Jidong |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
WANG,Tingting ZHANG,Dan SONG,Tao SUN,Mengdi ZHANG,Jidong |
dc.subject.por.fl_str_mv |
transforming growth factor β1 TGF-β1 testicular genesis biological functions polypeptide growth |
topic |
transforming growth factor β1 TGF-β1 testicular genesis biological functions polypeptide growth |
description |
Abstract Transforming growth factor β1 (TGF-β1) is a polypeptide growth factor with various biological activities. Recent studies have shown that this growth factor and they receptors are expressed in human Leydig cells, Sertoli cells, spermatogonia, spermatocytes and sperm cells after birth, and are involved in the endocrine regulation of spermatogenesis. However, there is no report on the expression of TGF-β in human embryonic testis. TGF-β1 is a peptide growth factor widely distributed in germ cells at various levels in the testis, regulating the function of the testes and maintaining the stability of the testis environment by acting on various cells. This review summarizes the research progress of TGF-β1 in human testis. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000102020 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000102020 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/fst.22521 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos |
publisher.none.fl_str_mv |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos |
dc.source.none.fl_str_mv |
Food Science and Technology v.42 2022 reponame:Food Science and Technology (Campinas) instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) instacron:SBCTA |
instname_str |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) |
instacron_str |
SBCTA |
institution |
SBCTA |
reponame_str |
Food Science and Technology (Campinas) |
collection |
Food Science and Technology (Campinas) |
repository.name.fl_str_mv |
Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) |
repository.mail.fl_str_mv |
||revista@sbcta.org.br |
_version_ |
1752126335899140096 |