Diosgenin: an important natural pharmaceutical active ingredient

Detalhes bibliográficos
Autor(a) principal: HUANG,Nannan
Data de Publicação: 2022
Outros Autores: YU,Dan, WU,Junkai, DU,Xiaowei
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Food Science and Technology (Campinas)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000102035
Resumo: Abstract Diosgenin is a steroidal saponin isolated from dioscorea opposita, which has been proven to have anti-cancer, anti-inflammatory, anti-thrombotic and immune system modulating effects in a large number of pharmacological tests. Diosgenin is also one of the important raw materials for the synthesis of steroidal drugs, and structural modification of diosgenin to obtain diosgenin derivatives can not only improve the solubility and dissolution, but also enhance their pharmacological effects. This paper reviews the synthetic reactions, pharmacological effects of diosgenin and its derivatives, aiming to provide detailed information for the further development and application of diosgenin, which is important to improve the utilization value of diosgenin.
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spelling Diosgenin: an important natural pharmaceutical active ingredientdiosgeninanti-canceranti-inflammatoryanti-thromboticAbstract Diosgenin is a steroidal saponin isolated from dioscorea opposita, which has been proven to have anti-cancer, anti-inflammatory, anti-thrombotic and immune system modulating effects in a large number of pharmacological tests. Diosgenin is also one of the important raw materials for the synthesis of steroidal drugs, and structural modification of diosgenin to obtain diosgenin derivatives can not only improve the solubility and dissolution, but also enhance their pharmacological effects. This paper reviews the synthetic reactions, pharmacological effects of diosgenin and its derivatives, aiming to provide detailed information for the further development and application of diosgenin, which is important to improve the utilization value of diosgenin.Sociedade Brasileira de Ciência e Tecnologia de Alimentos2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000102035Food Science and Technology v.42 2022reponame:Food Science and Technology (Campinas)instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)instacron:SBCTA10.1590/fst.94521info:eu-repo/semantics/openAccessHUANG,NannanYU,DanWU,JunkaiDU,Xiaoweieng2022-03-22T00:00:00Zoai:scielo:S0101-20612022000102035Revistahttp://www.scielo.br/ctaONGhttps://old.scielo.br/oai/scielo-oai.php||revista@sbcta.org.br1678-457X0101-2061opendoar:2022-03-22T00:00Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)false
dc.title.none.fl_str_mv Diosgenin: an important natural pharmaceutical active ingredient
title Diosgenin: an important natural pharmaceutical active ingredient
spellingShingle Diosgenin: an important natural pharmaceutical active ingredient
HUANG,Nannan
diosgenin
anti-cancer
anti-inflammatory
anti-thrombotic
title_short Diosgenin: an important natural pharmaceutical active ingredient
title_full Diosgenin: an important natural pharmaceutical active ingredient
title_fullStr Diosgenin: an important natural pharmaceutical active ingredient
title_full_unstemmed Diosgenin: an important natural pharmaceutical active ingredient
title_sort Diosgenin: an important natural pharmaceutical active ingredient
author HUANG,Nannan
author_facet HUANG,Nannan
YU,Dan
WU,Junkai
DU,Xiaowei
author_role author
author2 YU,Dan
WU,Junkai
DU,Xiaowei
author2_role author
author
author
dc.contributor.author.fl_str_mv HUANG,Nannan
YU,Dan
WU,Junkai
DU,Xiaowei
dc.subject.por.fl_str_mv diosgenin
anti-cancer
anti-inflammatory
anti-thrombotic
topic diosgenin
anti-cancer
anti-inflammatory
anti-thrombotic
description Abstract Diosgenin is a steroidal saponin isolated from dioscorea opposita, which has been proven to have anti-cancer, anti-inflammatory, anti-thrombotic and immune system modulating effects in a large number of pharmacological tests. Diosgenin is also one of the important raw materials for the synthesis of steroidal drugs, and structural modification of diosgenin to obtain diosgenin derivatives can not only improve the solubility and dissolution, but also enhance their pharmacological effects. This paper reviews the synthetic reactions, pharmacological effects of diosgenin and its derivatives, aiming to provide detailed information for the further development and application of diosgenin, which is important to improve the utilization value of diosgenin.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000102035
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000102035
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/fst.94521
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Ciência e Tecnologia de Alimentos
publisher.none.fl_str_mv Sociedade Brasileira de Ciência e Tecnologia de Alimentos
dc.source.none.fl_str_mv Food Science and Technology v.42 2022
reponame:Food Science and Technology (Campinas)
instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
instacron:SBCTA
instname_str Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
instacron_str SBCTA
institution SBCTA
reponame_str Food Science and Technology (Campinas)
collection Food Science and Technology (Campinas)
repository.name.fl_str_mv Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
repository.mail.fl_str_mv ||revista@sbcta.org.br
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