Antimicrobial activity of Rhus Coriaria L. and Salvia Urmiensis bunge against some food-borne pathogens and identification of active components using molecular networking and docking analyses
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Food Science and Technology (Campinas) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000100907 |
Resumo: | Abstract This research aimed to evaluate the in vitro antibacterial activity of methanol extracts of Rhus coriaria L. (sumac) and Salvia urmiensis Bunge against some food-borne pathogens, survey the phytochemical constituents of the extracts, and their activity against some drug targets in pathogens. The antibacterial activity of the extracts was evaluated against six pathogens using agar well diffusion and broth microdilution methods. Both extracts exhibited antibacterial activity and the highest activity was obtained by sumac against Staphylococcus aureus (27.7 ± 0.8 mm). The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of sumac against tested bacteria were in the range of 0.125-0.5 and 0.25-1 mg/mL, respectively. S. urmiensis showed weaker antimicrobial activity with a MIC range of 2-4 mg/mL. A molecular networking analysis of extracts resulted in annotation of 18 and 12 compounds from the methanol extracts of S. urmiensis and sumac respectively, which mainly were related to flavonoids. Molecular docking analysis could effectively characterize some glycosylated flavonoids with a high binding affinity to the studied enzymes. This study confirmed the efficacy of sumac and S. urmiensis extracts as natural antimicrobial agents and introduced a wide range of compounds, which can be used in food preservation to control foodborne pathogens in food. |
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Antimicrobial activity of Rhus Coriaria L. and Salvia Urmiensis bunge against some food-borne pathogens and identification of active components using molecular networking and docking analysesRhus coriaria L.Salvia urmiensis Bungemolecular dockinganti-bacterial agentsStaphylococcus aureusAbstract This research aimed to evaluate the in vitro antibacterial activity of methanol extracts of Rhus coriaria L. (sumac) and Salvia urmiensis Bunge against some food-borne pathogens, survey the phytochemical constituents of the extracts, and their activity against some drug targets in pathogens. The antibacterial activity of the extracts was evaluated against six pathogens using agar well diffusion and broth microdilution methods. Both extracts exhibited antibacterial activity and the highest activity was obtained by sumac against Staphylococcus aureus (27.7 ± 0.8 mm). The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of sumac against tested bacteria were in the range of 0.125-0.5 and 0.25-1 mg/mL, respectively. S. urmiensis showed weaker antimicrobial activity with a MIC range of 2-4 mg/mL. A molecular networking analysis of extracts resulted in annotation of 18 and 12 compounds from the methanol extracts of S. urmiensis and sumac respectively, which mainly were related to flavonoids. Molecular docking analysis could effectively characterize some glycosylated flavonoids with a high binding affinity to the studied enzymes. This study confirmed the efficacy of sumac and S. urmiensis extracts as natural antimicrobial agents and introduced a wide range of compounds, which can be used in food preservation to control foodborne pathogens in food.Sociedade Brasileira de Ciência e Tecnologia de Alimentos2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000100907Food Science and Technology v.42 2022reponame:Food Science and Technology (Campinas)instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)instacron:SBCTA10.1590/fst.08221info:eu-repo/semantics/openAccessGHANE,MaryamBABAEEKHOU,LalehSHAMS,Masumeheng2022-03-15T00:00:00Zoai:scielo:S0101-20612022000100907Revistahttp://www.scielo.br/ctaONGhttps://old.scielo.br/oai/scielo-oai.php||revista@sbcta.org.br1678-457X0101-2061opendoar:2022-03-15T00:00Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)false |
dc.title.none.fl_str_mv |
Antimicrobial activity of Rhus Coriaria L. and Salvia Urmiensis bunge against some food-borne pathogens and identification of active components using molecular networking and docking analyses |
title |
Antimicrobial activity of Rhus Coriaria L. and Salvia Urmiensis bunge against some food-borne pathogens and identification of active components using molecular networking and docking analyses |
spellingShingle |
Antimicrobial activity of Rhus Coriaria L. and Salvia Urmiensis bunge against some food-borne pathogens and identification of active components using molecular networking and docking analyses GHANE,Maryam Rhus coriaria L. Salvia urmiensis Bunge molecular docking anti-bacterial agents Staphylococcus aureus |
title_short |
Antimicrobial activity of Rhus Coriaria L. and Salvia Urmiensis bunge against some food-borne pathogens and identification of active components using molecular networking and docking analyses |
title_full |
Antimicrobial activity of Rhus Coriaria L. and Salvia Urmiensis bunge against some food-borne pathogens and identification of active components using molecular networking and docking analyses |
title_fullStr |
Antimicrobial activity of Rhus Coriaria L. and Salvia Urmiensis bunge against some food-borne pathogens and identification of active components using molecular networking and docking analyses |
title_full_unstemmed |
Antimicrobial activity of Rhus Coriaria L. and Salvia Urmiensis bunge against some food-borne pathogens and identification of active components using molecular networking and docking analyses |
title_sort |
Antimicrobial activity of Rhus Coriaria L. and Salvia Urmiensis bunge against some food-borne pathogens and identification of active components using molecular networking and docking analyses |
author |
GHANE,Maryam |
author_facet |
GHANE,Maryam BABAEEKHOU,Laleh SHAMS,Masumeh |
author_role |
author |
author2 |
BABAEEKHOU,Laleh SHAMS,Masumeh |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
GHANE,Maryam BABAEEKHOU,Laleh SHAMS,Masumeh |
dc.subject.por.fl_str_mv |
Rhus coriaria L. Salvia urmiensis Bunge molecular docking anti-bacterial agents Staphylococcus aureus |
topic |
Rhus coriaria L. Salvia urmiensis Bunge molecular docking anti-bacterial agents Staphylococcus aureus |
description |
Abstract This research aimed to evaluate the in vitro antibacterial activity of methanol extracts of Rhus coriaria L. (sumac) and Salvia urmiensis Bunge against some food-borne pathogens, survey the phytochemical constituents of the extracts, and their activity against some drug targets in pathogens. The antibacterial activity of the extracts was evaluated against six pathogens using agar well diffusion and broth microdilution methods. Both extracts exhibited antibacterial activity and the highest activity was obtained by sumac against Staphylococcus aureus (27.7 ± 0.8 mm). The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of sumac against tested bacteria were in the range of 0.125-0.5 and 0.25-1 mg/mL, respectively. S. urmiensis showed weaker antimicrobial activity with a MIC range of 2-4 mg/mL. A molecular networking analysis of extracts resulted in annotation of 18 and 12 compounds from the methanol extracts of S. urmiensis and sumac respectively, which mainly were related to flavonoids. Molecular docking analysis could effectively characterize some glycosylated flavonoids with a high binding affinity to the studied enzymes. This study confirmed the efficacy of sumac and S. urmiensis extracts as natural antimicrobial agents and introduced a wide range of compounds, which can be used in food preservation to control foodborne pathogens in food. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000100907 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000100907 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/fst.08221 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos |
publisher.none.fl_str_mv |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos |
dc.source.none.fl_str_mv |
Food Science and Technology v.42 2022 reponame:Food Science and Technology (Campinas) instname:Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) instacron:SBCTA |
instname_str |
Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) |
instacron_str |
SBCTA |
institution |
SBCTA |
reponame_str |
Food Science and Technology (Campinas) |
collection |
Food Science and Technology (Campinas) |
repository.name.fl_str_mv |
Food Science and Technology (Campinas) - Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) |
repository.mail.fl_str_mv |
||revista@sbcta.org.br |
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1752126333356343296 |