Lucio's phenomenon: another case reported in Brazil

Detalhes bibliográficos
Autor(a) principal: Monteiro,Rodrigo
Data de Publicação: 2012
Outros Autores: Tiezzi,Marcelo Guimarães, Abreu,Marilda Aparecida Milanez Morgado de, Oliveira,Claudia Cardoso Macedo de, Roncada,Eduardo Vinícios Mendes, Ortigosa,Luciena Cegatto Martins
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000200017
Resumo: Lucio's phenomenon is defined as a variant of type 2 leprosy reaction. It is a rare event, occurring in the evolution of leprosy of Lucio and other forms of lepromatous leprosy. It has an exacerbated proliferation of Hansen bacilli in its pathophysiology, which invade blood vessel walls and injure endothelial cells, causing endothelial proliferation and decreasing the vascular lumen. This fact, associated with inflammatory reactions and changes in the coagulation system causes vascular thrombosis, ischemia, infarction and tissue necrosis, leading to the histopathological characteristic of the phenomenon. We report a case of lepromatous leprosy with irregular treatment that developed Lucio's phenomenon. Treatment with multidrug therapy, antibiotics, steroids and thalidomide achieved a favorable outcome.
id SBD-1_009eaa034fdeb660571d8aa2cba0b701
oai_identifier_str oai:scielo:S0365-05962012000200017
network_acronym_str SBD-1
network_name_str Anais brasileiros de dermatologia (Online)
repository_id_str
spelling Lucio's phenomenon: another case reported in BrazilBlood coagulationBlood coagulation disordersDrug therapyErythema nodosumLeprosy, lepromatousTherapeuticsThrombosisLucio's phenomenon is defined as a variant of type 2 leprosy reaction. It is a rare event, occurring in the evolution of leprosy of Lucio and other forms of lepromatous leprosy. It has an exacerbated proliferation of Hansen bacilli in its pathophysiology, which invade blood vessel walls and injure endothelial cells, causing endothelial proliferation and decreasing the vascular lumen. This fact, associated with inflammatory reactions and changes in the coagulation system causes vascular thrombosis, ischemia, infarction and tissue necrosis, leading to the histopathological characteristic of the phenomenon. We report a case of lepromatous leprosy with irregular treatment that developed Lucio's phenomenon. Treatment with multidrug therapy, antibiotics, steroids and thalidomide achieved a favorable outcome.Sociedade Brasileira de Dermatologia2012-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000200017Anais Brasileiros de Dermatologia v.87 n.2 2012reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/S0365-05962012000200017info:eu-repo/semantics/openAccessMonteiro,RodrigoTiezzi,Marcelo GuimarãesAbreu,Marilda Aparecida Milanez Morgado deOliveira,Claudia Cardoso Macedo deRoncada,Eduardo Vinícios MendesOrtigosa,Luciena Cegatto Martinseng2012-05-03T00:00:00Zoai:scielo:S0365-05962012000200017Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2012-05-03T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Lucio's phenomenon: another case reported in Brazil
title Lucio's phenomenon: another case reported in Brazil
spellingShingle Lucio's phenomenon: another case reported in Brazil
Monteiro,Rodrigo
Blood coagulation
Blood coagulation disorders
Drug therapy
Erythema nodosum
Leprosy, lepromatous
Therapeutics
Thrombosis
title_short Lucio's phenomenon: another case reported in Brazil
title_full Lucio's phenomenon: another case reported in Brazil
title_fullStr Lucio's phenomenon: another case reported in Brazil
title_full_unstemmed Lucio's phenomenon: another case reported in Brazil
title_sort Lucio's phenomenon: another case reported in Brazil
author Monteiro,Rodrigo
author_facet Monteiro,Rodrigo
Tiezzi,Marcelo Guimarães
Abreu,Marilda Aparecida Milanez Morgado de
Oliveira,Claudia Cardoso Macedo de
Roncada,Eduardo Vinícios Mendes
Ortigosa,Luciena Cegatto Martins
author_role author
author2 Tiezzi,Marcelo Guimarães
Abreu,Marilda Aparecida Milanez Morgado de
Oliveira,Claudia Cardoso Macedo de
Roncada,Eduardo Vinícios Mendes
Ortigosa,Luciena Cegatto Martins
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Monteiro,Rodrigo
Tiezzi,Marcelo Guimarães
Abreu,Marilda Aparecida Milanez Morgado de
Oliveira,Claudia Cardoso Macedo de
Roncada,Eduardo Vinícios Mendes
Ortigosa,Luciena Cegatto Martins
dc.subject.por.fl_str_mv Blood coagulation
Blood coagulation disorders
Drug therapy
Erythema nodosum
Leprosy, lepromatous
Therapeutics
Thrombosis
topic Blood coagulation
Blood coagulation disorders
Drug therapy
Erythema nodosum
Leprosy, lepromatous
Therapeutics
Thrombosis
description Lucio's phenomenon is defined as a variant of type 2 leprosy reaction. It is a rare event, occurring in the evolution of leprosy of Lucio and other forms of lepromatous leprosy. It has an exacerbated proliferation of Hansen bacilli in its pathophysiology, which invade blood vessel walls and injure endothelial cells, causing endothelial proliferation and decreasing the vascular lumen. This fact, associated with inflammatory reactions and changes in the coagulation system causes vascular thrombosis, ischemia, infarction and tissue necrosis, leading to the histopathological characteristic of the phenomenon. We report a case of lepromatous leprosy with irregular treatment that developed Lucio's phenomenon. Treatment with multidrug therapy, antibiotics, steroids and thalidomide achieved a favorable outcome.
publishDate 2012
dc.date.none.fl_str_mv 2012-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000200017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000200017
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0365-05962012000200017
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.87 n.2 2012
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
_version_ 1752126417936580608

Registros relacionados