Lucio's Phenomenon. Case study of an exceptional response to treatment exclusively with multibacillary multidrug therapy

• Autor(a) principal: Peixoto,Amanda Braga
• Data de Publicação: 2013
• Outros Autores: Portela,Poliana Santin, Leal,Fabiano Roberto Pereira de Carvalho, Brotas,Arles Martins, Rodrigues,Nilton Carlos dos Santos
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Anais brasileiros de dermatologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000800093
• topic: Drug therapy, combination; Leprosy, lepromatous; Treatment outcome

Lucio's phenomenon represents a serious cutaneous necrotizing reaction, which can occur with Lucio's leprosy and also in other forms of lepromatous leprosy. The authors discuss the case of a 63-year-old male patient presenting with ulcers and necrotic cutaneous lesions on the limbs, torso and face, associated with recurring sinusitis, hoarseness and a weight loss of 25 kilos over the last year. Bacilloscopy of intradermal scrapings showed a bacilloscopic index of 5 and the histopathological findings were compatible with the diagnosis of Lucio's phenomenon. The chosen treatment was exclusively multibacillary multidrug therapy, resulting in important dermatological improvement after one month of therapy. The authors present an impressive case of Lucio's phenomenon with an exceptional response to treatment exclusively with multibacillary multidrug therapy.