Hyperpigmentation as a peculiar presentation of mycosis fungoides

Detalhes bibliográficos
Autor(a) principal: Lu,Ying-Yi
Data de Publicação: 2017
Outros Autores: Wu,Chieh-Hsin, Lu,Chun-Ching, Hong,Chien-Hui
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100092
Resumo: Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy.
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spelling Hyperpigmentation as a peculiar presentation of mycosis fungoidesAntigens, CD8HyperpigmentationMycosis fungoidesAbstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy.Sociedade Brasileira de Dermatologia2017-01-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100092Anais Brasileiros de Dermatologia v.92 n.5 suppl.1 2017reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20175544info:eu-repo/semantics/openAccessLu,Ying-YiWu,Chieh-HsinLu,Chun-ChingHong,Chien-Huieng2017-12-13T00:00:00Zoai:scielo:S0365-05962017001100092Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2017-12-13T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Hyperpigmentation as a peculiar presentation of mycosis fungoides
title Hyperpigmentation as a peculiar presentation of mycosis fungoides
spellingShingle Hyperpigmentation as a peculiar presentation of mycosis fungoides
Lu,Ying-Yi
Antigens, CD8
Hyperpigmentation
Mycosis fungoides
title_short Hyperpigmentation as a peculiar presentation of mycosis fungoides
title_full Hyperpigmentation as a peculiar presentation of mycosis fungoides
title_fullStr Hyperpigmentation as a peculiar presentation of mycosis fungoides
title_full_unstemmed Hyperpigmentation as a peculiar presentation of mycosis fungoides
title_sort Hyperpigmentation as a peculiar presentation of mycosis fungoides
author Lu,Ying-Yi
author_facet Lu,Ying-Yi
Wu,Chieh-Hsin
Lu,Chun-Ching
Hong,Chien-Hui
author_role author
author2 Wu,Chieh-Hsin
Lu,Chun-Ching
Hong,Chien-Hui
author2_role author
author
author
dc.contributor.author.fl_str_mv Lu,Ying-Yi
Wu,Chieh-Hsin
Lu,Chun-Ching
Hong,Chien-Hui
dc.subject.por.fl_str_mv Antigens, CD8
Hyperpigmentation
Mycosis fungoides
topic Antigens, CD8
Hyperpigmentation
Mycosis fungoides
description Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100092
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20175544
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.92 n.5 suppl.1 2017
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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