Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease

Detalhes bibliográficos
Autor(a) principal: Lage,Renan
Data de Publicação: 2015
Outros Autores: Biccigo,Danilo Guerreiro Zeolo, Santos,Felipe Borba Calixto, Chimara,Erica, Pereira,Elisangela Samartin Pegas, Costa,Adilson da
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104
Resumo: Around 50 mycobacteria species cause human disease. Immunosuppressive states predispose to non-tuberculous mycobaterium infection, such as Mycobacterium chelonae: AFB, non-tuberculous, fast growth of low virulence and uncommon as a human pathogen. It may compromise the skin and soft tissues, lungs, lymph nodes and there is also a disseminated presentation. The diagnosis involves AFB identification and culture on Agar and Lowenstein-Jensen medium base. A 41-year-old female with MCTD (LES predominance) is reported, presenting painless nodules in the right forearm. She denied local trauma. Immunosuppressed with prednisone and cyclophosphamide for 24 months. Lesion biopsy has demonstrated positive bacilloscopy (Ziehl-Neelsen stain) and M.chelonae in culture (Lowenstein-Jensen medium base), therefore clarithromycin treatment has been started (best therapy choice in the literature).
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spelling Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue diseaseClarithromycinImmunosuppressionMixed connective tissue diseaseMycobacterium chelonaeMycobacterium fortuitumNontuberculous mycobacteriaPrednisoneSkinVirulenceAround 50 mycobacteria species cause human disease. Immunosuppressive states predispose to non-tuberculous mycobaterium infection, such as Mycobacterium chelonae: AFB, non-tuberculous, fast growth of low virulence and uncommon as a human pathogen. It may compromise the skin and soft tissues, lungs, lymph nodes and there is also a disseminated presentation. The diagnosis involves AFB identification and culture on Agar and Lowenstein-Jensen medium base. A 41-year-old female with MCTD (LES predominance) is reported, presenting painless nodules in the right forearm. She denied local trauma. Immunosuppressed with prednisone and cyclophosphamide for 24 months. Lesion biopsy has demonstrated positive bacilloscopy (Ziehl-Neelsen stain) and M.chelonae in culture (Lowenstein-Jensen medium base), therefore clarithromycin treatment has been started (best therapy choice in the literature).Sociedade Brasileira de Dermatologia2015-02-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104Anais Brasileiros de Dermatologia v.90 n.1 2015reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20152276info:eu-repo/semantics/openAccessLage,RenanBiccigo,Danilo Guerreiro ZeoloSantos,Felipe Borba CalixtoChimara,EricaPereira,Elisangela Samartin PegasCosta,Adilson daeng2015-02-03T00:00:00Zoai:scielo:S0365-05962015000100104Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2015-02-03T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease
title Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease
spellingShingle Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease
Lage,Renan
Clarithromycin
Immunosuppression
Mixed connective tissue disease
Mycobacterium chelonae
Mycobacterium fortuitum
Nontuberculous mycobacteria
Prednisone
Skin
Virulence
title_short Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease
title_full Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease
title_fullStr Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease
title_full_unstemmed Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease
title_sort Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease
author Lage,Renan
author_facet Lage,Renan
Biccigo,Danilo Guerreiro Zeolo
Santos,Felipe Borba Calixto
Chimara,Erica
Pereira,Elisangela Samartin Pegas
Costa,Adilson da
author_role author
author2 Biccigo,Danilo Guerreiro Zeolo
Santos,Felipe Borba Calixto
Chimara,Erica
Pereira,Elisangela Samartin Pegas
Costa,Adilson da
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lage,Renan
Biccigo,Danilo Guerreiro Zeolo
Santos,Felipe Borba Calixto
Chimara,Erica
Pereira,Elisangela Samartin Pegas
Costa,Adilson da
dc.subject.por.fl_str_mv Clarithromycin
Immunosuppression
Mixed connective tissue disease
Mycobacterium chelonae
Mycobacterium fortuitum
Nontuberculous mycobacteria
Prednisone
Skin
Virulence
topic Clarithromycin
Immunosuppression
Mixed connective tissue disease
Mycobacterium chelonae
Mycobacterium fortuitum
Nontuberculous mycobacteria
Prednisone
Skin
Virulence
description Around 50 mycobacteria species cause human disease. Immunosuppressive states predispose to non-tuberculous mycobaterium infection, such as Mycobacterium chelonae: AFB, non-tuberculous, fast growth of low virulence and uncommon as a human pathogen. It may compromise the skin and soft tissues, lungs, lymph nodes and there is also a disseminated presentation. The diagnosis involves AFB identification and culture on Agar and Lowenstein-Jensen medium base. A 41-year-old female with MCTD (LES predominance) is reported, presenting painless nodules in the right forearm. She denied local trauma. Immunosuppressed with prednisone and cyclophosphamide for 24 months. Lesion biopsy has demonstrated positive bacilloscopy (Ziehl-Neelsen stain) and M.chelonae in culture (Lowenstein-Jensen medium base), therefore clarithromycin treatment has been started (best therapy choice in the literature).
publishDate 2015
dc.date.none.fl_str_mv 2015-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20152276
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.90 n.1 2015
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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