Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects

Detalhes bibliográficos
Autor(a) principal: Vieira,Renata Aparecida Martinez Antunes Ribeiro
Data de Publicação: 2012
Outros Autores: Minicucci,Eliana Maria, Marques,Mariangela Esther Alencar, Marques,Silvio Alencar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000100013
Resumo: Actinic cheilitis is the main precancerous lesion of the lip. Squamous cell carcinoma of the lip is reported together with oral carcinomas in the Brazilian official statistics. Overall, they account for 40% of the head and neck carcinomas. In general, physicians and dentists know little about what causes oral tumor development and progression. Tumor suppressor genes and cell proliferation regulatory proteins play a role in the progression of actinic cheilitis to squamous cell carcinoma and in its biological behavior. Knowledge on prognostic and diagnostic markers has a positive impact on the follow-up of these patients.
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spelling Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspectsCarcinomasquamous cellCheilitisCyclin-dependent kinase inhibitor proteinsCyclin D1Protooncogene proteins c-bcl-2Tumor suppressor protein p53Actinic cheilitis is the main precancerous lesion of the lip. Squamous cell carcinoma of the lip is reported together with oral carcinomas in the Brazilian official statistics. Overall, they account for 40% of the head and neck carcinomas. In general, physicians and dentists know little about what causes oral tumor development and progression. Tumor suppressor genes and cell proliferation regulatory proteins play a role in the progression of actinic cheilitis to squamous cell carcinoma and in its biological behavior. Knowledge on prognostic and diagnostic markers has a positive impact on the follow-up of these patients.Sociedade Brasileira de Dermatologia2012-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000100013Anais Brasileiros de Dermatologia v.87 n.1 2012reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/S0365-05962012000100013info:eu-repo/semantics/openAccessVieira,Renata Aparecida Martinez Antunes RibeiroMinicucci,Eliana MariaMarques,Mariangela Esther AlencarMarques,Silvio Alencareng2012-04-02T00:00:00Zoai:scielo:S0365-05962012000100013Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2012-04-02T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects
title Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects
spellingShingle Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects
Vieira,Renata Aparecida Martinez Antunes Ribeiro
Carcinoma
squamous cell
Cheilitis
Cyclin-dependent kinase inhibitor proteins
Cyclin D1
Protooncogene proteins c-bcl-2
Tumor suppressor protein p53
title_short Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects
title_full Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects
title_fullStr Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects
title_full_unstemmed Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects
title_sort Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects
author Vieira,Renata Aparecida Martinez Antunes Ribeiro
author_facet Vieira,Renata Aparecida Martinez Antunes Ribeiro
Minicucci,Eliana Maria
Marques,Mariangela Esther Alencar
Marques,Silvio Alencar
author_role author
author2 Minicucci,Eliana Maria
Marques,Mariangela Esther Alencar
Marques,Silvio Alencar
author2_role author
author
author
dc.contributor.author.fl_str_mv Vieira,Renata Aparecida Martinez Antunes Ribeiro
Minicucci,Eliana Maria
Marques,Mariangela Esther Alencar
Marques,Silvio Alencar
dc.subject.por.fl_str_mv Carcinoma
squamous cell
Cheilitis
Cyclin-dependent kinase inhibitor proteins
Cyclin D1
Protooncogene proteins c-bcl-2
Tumor suppressor protein p53
topic Carcinoma
squamous cell
Cheilitis
Cyclin-dependent kinase inhibitor proteins
Cyclin D1
Protooncogene proteins c-bcl-2
Tumor suppressor protein p53
description Actinic cheilitis is the main precancerous lesion of the lip. Squamous cell carcinoma of the lip is reported together with oral carcinomas in the Brazilian official statistics. Overall, they account for 40% of the head and neck carcinomas. In general, physicians and dentists know little about what causes oral tumor development and progression. Tumor suppressor genes and cell proliferation regulatory proteins play a role in the progression of actinic cheilitis to squamous cell carcinoma and in its biological behavior. Knowledge on prognostic and diagnostic markers has a positive impact on the follow-up of these patients.
publishDate 2012
dc.date.none.fl_str_mv 2012-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000100013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000100013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0365-05962012000100013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.87 n.1 2012
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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