Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects

Detalhes bibliográficos
Autor(a) principal: Bicca,Eduardo de Barros Coelho
Data de Publicação: 2011
Outros Autores: Almeida,Fabiano Bonow de, Pinto,Giselle Martins, Castro,Luis Antônio Suíta de, Almeida Jr,Hiram Larangeira de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700043
Resumo: A 12-year-old boy with difficulty in wound healing and scars of unusual appearance was examined. Thin, shiny and protruding skin, characterizing pseudotumoral lesions, was observed on his knees and elbows. Loose joints and increased skin elasticity were also observed. Light microscopy showed rare collagen bundles and loosely dispersed collagen fibers. Irregularly distributed elastic tissue was observed, and transmission electron microscopy revealed disorganized collagen fibers. In cross sections under high magnifications, fibers of varying diameters could be seen, as well as an irregular fiber outline. Scanning electron microscopy of the dermis showed disorganized collagen fibers, which were rarely arranged in bundles. Isolated and crossed-over fibers were also found
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spelling Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspectsCollagen type VEhlers-Danlos syndromeMicroscopy, electron, scanningMicroscopy, electron, scanning transmissionA 12-year-old boy with difficulty in wound healing and scars of unusual appearance was examined. Thin, shiny and protruding skin, characterizing pseudotumoral lesions, was observed on his knees and elbows. Loose joints and increased skin elasticity were also observed. Light microscopy showed rare collagen bundles and loosely dispersed collagen fibers. Irregularly distributed elastic tissue was observed, and transmission electron microscopy revealed disorganized collagen fibers. In cross sections under high magnifications, fibers of varying diameters could be seen, as well as an irregular fiber outline. Scanning electron microscopy of the dermis showed disorganized collagen fibers, which were rarely arranged in bundles. Isolated and crossed-over fibers were also foundSociedade Brasileira de Dermatologia2011-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700043Anais Brasileiros de Dermatologia v.86 n.4 suppl.1 2011reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/S0365-05962011000700043info:eu-repo/semantics/openAccessBicca,Eduardo de Barros CoelhoAlmeida,Fabiano Bonow dePinto,Giselle MartinsCastro,Luis Antônio Suíta deAlmeida Jr,Hiram Larangeira deeng2016-07-12T00:00:00Zoai:scielo:S0365-05962011000700043Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2016-07-12T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects
title Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects
spellingShingle Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects
Bicca,Eduardo de Barros Coelho
Collagen type V
Ehlers-Danlos syndrome
Microscopy, electron, scanning
Microscopy, electron, scanning transmission
title_short Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects
title_full Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects
title_fullStr Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects
title_full_unstemmed Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects
title_sort Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects
author Bicca,Eduardo de Barros Coelho
author_facet Bicca,Eduardo de Barros Coelho
Almeida,Fabiano Bonow de
Pinto,Giselle Martins
Castro,Luis Antônio Suíta de
Almeida Jr,Hiram Larangeira de
author_role author
author2 Almeida,Fabiano Bonow de
Pinto,Giselle Martins
Castro,Luis Antônio Suíta de
Almeida Jr,Hiram Larangeira de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Bicca,Eduardo de Barros Coelho
Almeida,Fabiano Bonow de
Pinto,Giselle Martins
Castro,Luis Antônio Suíta de
Almeida Jr,Hiram Larangeira de
dc.subject.por.fl_str_mv Collagen type V
Ehlers-Danlos syndrome
Microscopy, electron, scanning
Microscopy, electron, scanning transmission
topic Collagen type V
Ehlers-Danlos syndrome
Microscopy, electron, scanning
Microscopy, electron, scanning transmission
description A 12-year-old boy with difficulty in wound healing and scars of unusual appearance was examined. Thin, shiny and protruding skin, characterizing pseudotumoral lesions, was observed on his knees and elbows. Loose joints and increased skin elasticity were also observed. Light microscopy showed rare collagen bundles and loosely dispersed collagen fibers. Irregularly distributed elastic tissue was observed, and transmission electron microscopy revealed disorganized collagen fibers. In cross sections under high magnifications, fibers of varying diameters could be seen, as well as an irregular fiber outline. Scanning electron microscopy of the dermis showed disorganized collagen fibers, which were rarely arranged in bundles. Isolated and crossed-over fibers were also found
publishDate 2011
dc.date.none.fl_str_mv 2011-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700043
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700043
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0365-05962011000700043
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.86 n.4 suppl.1 2011
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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