Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Anais brasileiros de dermatologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700043 |
Resumo: | A 12-year-old boy with difficulty in wound healing and scars of unusual appearance was examined. Thin, shiny and protruding skin, characterizing pseudotumoral lesions, was observed on his knees and elbows. Loose joints and increased skin elasticity were also observed. Light microscopy showed rare collagen bundles and loosely dispersed collagen fibers. Irregularly distributed elastic tissue was observed, and transmission electron microscopy revealed disorganized collagen fibers. In cross sections under high magnifications, fibers of varying diameters could be seen, as well as an irregular fiber outline. Scanning electron microscopy of the dermis showed disorganized collagen fibers, which were rarely arranged in bundles. Isolated and crossed-over fibers were also found |
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Anais brasileiros de dermatologia (Online) |
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Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspectsCollagen type VEhlers-Danlos syndromeMicroscopy, electron, scanningMicroscopy, electron, scanning transmissionA 12-year-old boy with difficulty in wound healing and scars of unusual appearance was examined. Thin, shiny and protruding skin, characterizing pseudotumoral lesions, was observed on his knees and elbows. Loose joints and increased skin elasticity were also observed. Light microscopy showed rare collagen bundles and loosely dispersed collagen fibers. Irregularly distributed elastic tissue was observed, and transmission electron microscopy revealed disorganized collagen fibers. In cross sections under high magnifications, fibers of varying diameters could be seen, as well as an irregular fiber outline. Scanning electron microscopy of the dermis showed disorganized collagen fibers, which were rarely arranged in bundles. Isolated and crossed-over fibers were also foundSociedade Brasileira de Dermatologia2011-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700043Anais Brasileiros de Dermatologia v.86 n.4 suppl.1 2011reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/S0365-05962011000700043info:eu-repo/semantics/openAccessBicca,Eduardo de Barros CoelhoAlmeida,Fabiano Bonow dePinto,Giselle MartinsCastro,Luis Antônio Suíta deAlmeida Jr,Hiram Larangeira deeng2016-07-12T00:00:00Zoai:scielo:S0365-05962011000700043Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2016-07-12T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false |
dc.title.none.fl_str_mv |
Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects |
title |
Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects |
spellingShingle |
Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects Bicca,Eduardo de Barros Coelho Collagen type V Ehlers-Danlos syndrome Microscopy, electron, scanning Microscopy, electron, scanning transmission |
title_short |
Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects |
title_full |
Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects |
title_fullStr |
Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects |
title_full_unstemmed |
Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects |
title_sort |
Classical Ehlers-Danlos syndrome: clinical, Histological and ultrastructural aspects |
author |
Bicca,Eduardo de Barros Coelho |
author_facet |
Bicca,Eduardo de Barros Coelho Almeida,Fabiano Bonow de Pinto,Giselle Martins Castro,Luis Antônio Suíta de Almeida Jr,Hiram Larangeira de |
author_role |
author |
author2 |
Almeida,Fabiano Bonow de Pinto,Giselle Martins Castro,Luis Antônio Suíta de Almeida Jr,Hiram Larangeira de |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Bicca,Eduardo de Barros Coelho Almeida,Fabiano Bonow de Pinto,Giselle Martins Castro,Luis Antônio Suíta de Almeida Jr,Hiram Larangeira de |
dc.subject.por.fl_str_mv |
Collagen type V Ehlers-Danlos syndrome Microscopy, electron, scanning Microscopy, electron, scanning transmission |
topic |
Collagen type V Ehlers-Danlos syndrome Microscopy, electron, scanning Microscopy, electron, scanning transmission |
description |
A 12-year-old boy with difficulty in wound healing and scars of unusual appearance was examined. Thin, shiny and protruding skin, characterizing pseudotumoral lesions, was observed on his knees and elbows. Loose joints and increased skin elasticity were also observed. Light microscopy showed rare collagen bundles and loosely dispersed collagen fibers. Irregularly distributed elastic tissue was observed, and transmission electron microscopy revealed disorganized collagen fibers. In cross sections under high magnifications, fibers of varying diameters could be seen, as well as an irregular fiber outline. Scanning electron microscopy of the dermis showed disorganized collagen fibers, which were rarely arranged in bundles. Isolated and crossed-over fibers were also found |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700043 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000700043 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0365-05962011000700043 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
dc.source.none.fl_str_mv |
Anais Brasileiros de Dermatologia v.86 n.4 suppl.1 2011 reponame:Anais brasileiros de dermatologia (Online) instname:Sociedade Brasileira de Dermatologia (SBD) instacron:SBD |
instname_str |
Sociedade Brasileira de Dermatologia (SBD) |
instacron_str |
SBD |
institution |
SBD |
reponame_str |
Anais brasileiros de dermatologia (Online) |
collection |
Anais brasileiros de dermatologia (Online) |
repository.name.fl_str_mv |
Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD) |
repository.mail.fl_str_mv |
abd@sbd.org.br||revista@sbd.org.br |
_version_ |
1752126417858985984 |