Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection

Detalhes bibliográficos
Autor(a) principal: Pereira,Luiza Alonso
Data de Publicação: 2019
Outros Autores: Luz,Flávio Barbosa, Carneiro,Clívia Maria Moraes de Oliveira, Xavier,Ana Lucia Rampazzo, Kanaan,Salim, Miot,Hélio Amante
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000100010
Resumo: Abstract: Background: Most of the organism’s vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun’s UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection. Objectives: To evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30). Methods: Quasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (ΔVD) in serum level of 25-OH-VD (ng/ml) between the groups. Results: A statistically significant difference was identified between CO and SC groups [median (p25-p75)]: ΔVD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17. Study limitations: Laboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups. Conclusions: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults.
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spelling Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotectionSunscreening agentsUltraviolet raysVitamin DVitamin D deficiencyAbstract: Background: Most of the organism’s vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun’s UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection. Objectives: To evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30). Methods: Quasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (ΔVD) in serum level of 25-OH-VD (ng/ml) between the groups. Results: A statistically significant difference was identified between CO and SC groups [median (p25-p75)]: ΔVD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17. Study limitations: Laboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups. Conclusions: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults.Sociedade Brasileira de Dermatologia2019-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000100010Anais Brasileiros de Dermatologia v.94 n.1 2019reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20198070info:eu-repo/semantics/openAccessPereira,Luiza AlonsoLuz,Flávio BarbosaCarneiro,Clívia Maria Moraes de OliveiraXavier,Ana Lucia RampazzoKanaan,SalimMiot,Hélio Amanteeng2019-12-18T00:00:00Zoai:scielo:S0365-05962019000100010Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2019-12-18T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
title Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
spellingShingle Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
Pereira,Luiza Alonso
Sunscreening agents
Ultraviolet rays
Vitamin D
Vitamin D deficiency
title_short Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
title_full Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
title_fullStr Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
title_full_unstemmed Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
title_sort Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
author Pereira,Luiza Alonso
author_facet Pereira,Luiza Alonso
Luz,Flávio Barbosa
Carneiro,Clívia Maria Moraes de Oliveira
Xavier,Ana Lucia Rampazzo
Kanaan,Salim
Miot,Hélio Amante
author_role author
author2 Luz,Flávio Barbosa
Carneiro,Clívia Maria Moraes de Oliveira
Xavier,Ana Lucia Rampazzo
Kanaan,Salim
Miot,Hélio Amante
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira,Luiza Alonso
Luz,Flávio Barbosa
Carneiro,Clívia Maria Moraes de Oliveira
Xavier,Ana Lucia Rampazzo
Kanaan,Salim
Miot,Hélio Amante
dc.subject.por.fl_str_mv Sunscreening agents
Ultraviolet rays
Vitamin D
Vitamin D deficiency
topic Sunscreening agents
Ultraviolet rays
Vitamin D
Vitamin D deficiency
description Abstract: Background: Most of the organism’s vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun’s UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection. Objectives: To evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30). Methods: Quasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (ΔVD) in serum level of 25-OH-VD (ng/ml) between the groups. Results: A statistically significant difference was identified between CO and SC groups [median (p25-p75)]: ΔVD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17. Study limitations: Laboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups. Conclusions: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults.
publishDate 2019
dc.date.none.fl_str_mv 2019-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000100010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000100010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20198070
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.94 n.1 2019
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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