Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
Autor(a) principal: | |
---|---|
Data de Publicação: | 2019 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/abd1806-4841.20198070 http://hdl.handle.net/11449/185388 |
Resumo: | BACKGROUND: Most of the organism's vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun's UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection. OBJECTIVES: To evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30). METHODS: Quasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (Delta VD) in serum level of 25-OH-VD (ng/ml) between the groups. RESULTS: A statistically significant difference was identified between CO and SC groups [median (p25-p75)]: Delta VD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17. STUDY LIMITATIONS: Laboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups. CONCLUSIONS: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults. |
id |
UNSP_116e9d214da58423314439deb9f00b43 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/185388 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotectionSunscreening agentsUltraviolet raysVitamin DVitamin D deficiencyBACKGROUND: Most of the organism's vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun's UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection. OBJECTIVES: To evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30). METHODS: Quasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (Delta VD) in serum level of 25-OH-VD (ng/ml) between the groups. RESULTS: A statistically significant difference was identified between CO and SC groups [median (p25-p75)]: Delta VD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17. STUDY LIMITATIONS: Laboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups. CONCLUSIONS: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults.Sociedade Brasileira de DermatologiaSociedade Brasileira Dermatol, Rio De Janeiro, RJ, BrazilUniv Fed Fluminense, Dept Dermatol, Niteroi, RJ, BrazilUniv Fed Fluminense, Dept Dermatol, Discipline Dermatol, Niteroi, RJ, BrazilUniv Fed Para, Dept Dermatol, Discipline Dermatol, Belem, Para, BrazilUniv Fed Fluminenese, Dept Pathol Clin Biochem, Discipline Pathol, Niteroi, RJ, BrazilUniv Estadual Paulista, Dept Dermatol & Radiotherapy, Discipline Dermatol, Botucatu, SP, BrazilUniv Estadual Paulista, Dept Dermatol & Radiotherapy, Discipline Dermatol, Botucatu, SP, BrazilSoc Brasileira DermatologiaSociedade Brasileira DermatolUniversidade Federal Fluminense (UFF)Univ Fed ParaUniv Fed FlumineneseUniversidade Estadual Paulista (Unesp)Pereira, Luiza AlonsoLuz, Flavio BarbosaMoraes de Oliveira Carneiro, Clivia MariaRampazzo Xavier, Ana LuciaKanaan, SalimMiot, Helio Amante [UNESP]2019-10-04T12:35:08Z2019-10-04T12:35:08Z2019-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article56-61application/pdfhttp://dx.doi.org/10.1590/abd1806-4841.20198070Anais Brasileiros De Dermatologia. Rio De Janeiro Rj: Soc Brasileira Dermatologia, v. 94, n. 1, p. 56-61, 2019.0365-0596http://hdl.handle.net/11449/18538810.1590/abd1806-4841.20198070S0365-05962019000100010WOS:000457571600010S0365-05962019000100010.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAnais Brasileiros De Dermatologiainfo:eu-repo/semantics/openAccess2024-08-14T18:45:33Zoai:repositorio.unesp.br:11449/185388Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T18:45:33Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection |
title |
Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection |
spellingShingle |
Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection Pereira, Luiza Alonso Sunscreening agents Ultraviolet rays Vitamin D Vitamin D deficiency |
title_short |
Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection |
title_full |
Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection |
title_fullStr |
Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection |
title_full_unstemmed |
Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection |
title_sort |
Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection |
author |
Pereira, Luiza Alonso |
author_facet |
Pereira, Luiza Alonso Luz, Flavio Barbosa Moraes de Oliveira Carneiro, Clivia Maria Rampazzo Xavier, Ana Lucia Kanaan, Salim Miot, Helio Amante [UNESP] |
author_role |
author |
author2 |
Luz, Flavio Barbosa Moraes de Oliveira Carneiro, Clivia Maria Rampazzo Xavier, Ana Lucia Kanaan, Salim Miot, Helio Amante [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Sociedade Brasileira Dermatol Universidade Federal Fluminense (UFF) Univ Fed Para Univ Fed Fluminenese Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Pereira, Luiza Alonso Luz, Flavio Barbosa Moraes de Oliveira Carneiro, Clivia Maria Rampazzo Xavier, Ana Lucia Kanaan, Salim Miot, Helio Amante [UNESP] |
dc.subject.por.fl_str_mv |
Sunscreening agents Ultraviolet rays Vitamin D Vitamin D deficiency |
topic |
Sunscreening agents Ultraviolet rays Vitamin D Vitamin D deficiency |
description |
BACKGROUND: Most of the organism's vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun's UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection. OBJECTIVES: To evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30). METHODS: Quasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (Delta VD) in serum level of 25-OH-VD (ng/ml) between the groups. RESULTS: A statistically significant difference was identified between CO and SC groups [median (p25-p75)]: Delta VD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17. STUDY LIMITATIONS: Laboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups. CONCLUSIONS: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-04T12:35:08Z 2019-10-04T12:35:08Z 2019-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/abd1806-4841.20198070 Anais Brasileiros De Dermatologia. Rio De Janeiro Rj: Soc Brasileira Dermatologia, v. 94, n. 1, p. 56-61, 2019. 0365-0596 http://hdl.handle.net/11449/185388 10.1590/abd1806-4841.20198070 S0365-05962019000100010 WOS:000457571600010 S0365-05962019000100010.pdf |
url |
http://dx.doi.org/10.1590/abd1806-4841.20198070 http://hdl.handle.net/11449/185388 |
identifier_str_mv |
Anais Brasileiros De Dermatologia. Rio De Janeiro Rj: Soc Brasileira Dermatologia, v. 94, n. 1, p. 56-61, 2019. 0365-0596 10.1590/abd1806-4841.20198070 S0365-05962019000100010 WOS:000457571600010 S0365-05962019000100010.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Anais Brasileiros De Dermatologia |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
56-61 application/pdf |
dc.publisher.none.fl_str_mv |
Soc Brasileira Dermatologia |
publisher.none.fl_str_mv |
Soc Brasileira Dermatologia |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128127968215040 |