Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection

Detalhes bibliográficos
Autor(a) principal: Pereira, Luiza Alonso
Data de Publicação: 2019
Outros Autores: Luz, Flavio Barbosa, Moraes de Oliveira Carneiro, Clivia Maria, Rampazzo Xavier, Ana Lucia, Kanaan, Salim, Miot, Helio Amante [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/abd1806-4841.20198070
http://hdl.handle.net/11449/185388
Resumo: BACKGROUND: Most of the organism's vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun's UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection. OBJECTIVES: To evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30). METHODS: Quasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (Delta VD) in serum level of 25-OH-VD (ng/ml) between the groups. RESULTS: A statistically significant difference was identified between CO and SC groups [median (p25-p75)]: Delta VD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17. STUDY LIMITATIONS: Laboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups. CONCLUSIONS: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults.
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spelling Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotectionSunscreening agentsUltraviolet raysVitamin DVitamin D deficiencyBACKGROUND: Most of the organism's vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun's UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection. OBJECTIVES: To evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30). METHODS: Quasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (Delta VD) in serum level of 25-OH-VD (ng/ml) between the groups. RESULTS: A statistically significant difference was identified between CO and SC groups [median (p25-p75)]: Delta VD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17. STUDY LIMITATIONS: Laboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups. CONCLUSIONS: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults.Sociedade Brasileira de DermatologiaSociedade Brasileira Dermatol, Rio De Janeiro, RJ, BrazilUniv Fed Fluminense, Dept Dermatol, Niteroi, RJ, BrazilUniv Fed Fluminense, Dept Dermatol, Discipline Dermatol, Niteroi, RJ, BrazilUniv Fed Para, Dept Dermatol, Discipline Dermatol, Belem, Para, BrazilUniv Fed Fluminenese, Dept Pathol Clin Biochem, Discipline Pathol, Niteroi, RJ, BrazilUniv Estadual Paulista, Dept Dermatol & Radiotherapy, Discipline Dermatol, Botucatu, SP, BrazilUniv Estadual Paulista, Dept Dermatol & Radiotherapy, Discipline Dermatol, Botucatu, SP, BrazilSoc Brasileira DermatologiaSociedade Brasileira DermatolUniversidade Federal Fluminense (UFF)Univ Fed ParaUniv Fed FlumineneseUniversidade Estadual Paulista (Unesp)Pereira, Luiza AlonsoLuz, Flavio BarbosaMoraes de Oliveira Carneiro, Clivia MariaRampazzo Xavier, Ana LuciaKanaan, SalimMiot, Helio Amante [UNESP]2019-10-04T12:35:08Z2019-10-04T12:35:08Z2019-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article56-61application/pdfhttp://dx.doi.org/10.1590/abd1806-4841.20198070Anais Brasileiros De Dermatologia. Rio De Janeiro Rj: Soc Brasileira Dermatologia, v. 94, n. 1, p. 56-61, 2019.0365-0596http://hdl.handle.net/11449/18538810.1590/abd1806-4841.20198070S0365-05962019000100010WOS:000457571600010S0365-05962019000100010.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAnais Brasileiros De Dermatologiainfo:eu-repo/semantics/openAccess2024-08-14T18:45:33Zoai:repositorio.unesp.br:11449/185388Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T18:45:33Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
title Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
spellingShingle Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
Pereira, Luiza Alonso
Sunscreening agents
Ultraviolet rays
Vitamin D
Vitamin D deficiency
title_short Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
title_full Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
title_fullStr Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
title_full_unstemmed Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
title_sort Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
author Pereira, Luiza Alonso
author_facet Pereira, Luiza Alonso
Luz, Flavio Barbosa
Moraes de Oliveira Carneiro, Clivia Maria
Rampazzo Xavier, Ana Lucia
Kanaan, Salim
Miot, Helio Amante [UNESP]
author_role author
author2 Luz, Flavio Barbosa
Moraes de Oliveira Carneiro, Clivia Maria
Rampazzo Xavier, Ana Lucia
Kanaan, Salim
Miot, Helio Amante [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Sociedade Brasileira Dermatol
Universidade Federal Fluminense (UFF)
Univ Fed Para
Univ Fed Fluminenese
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Pereira, Luiza Alonso
Luz, Flavio Barbosa
Moraes de Oliveira Carneiro, Clivia Maria
Rampazzo Xavier, Ana Lucia
Kanaan, Salim
Miot, Helio Amante [UNESP]
dc.subject.por.fl_str_mv Sunscreening agents
Ultraviolet rays
Vitamin D
Vitamin D deficiency
topic Sunscreening agents
Ultraviolet rays
Vitamin D
Vitamin D deficiency
description BACKGROUND: Most of the organism's vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun's UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection. OBJECTIVES: To evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30). METHODS: Quasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (Delta VD) in serum level of 25-OH-VD (ng/ml) between the groups. RESULTS: A statistically significant difference was identified between CO and SC groups [median (p25-p75)]: Delta VD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17. STUDY LIMITATIONS: Laboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups. CONCLUSIONS: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults.
publishDate 2019
dc.date.none.fl_str_mv 2019-10-04T12:35:08Z
2019-10-04T12:35:08Z
2019-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/abd1806-4841.20198070
Anais Brasileiros De Dermatologia. Rio De Janeiro Rj: Soc Brasileira Dermatologia, v. 94, n. 1, p. 56-61, 2019.
0365-0596
http://hdl.handle.net/11449/185388
10.1590/abd1806-4841.20198070
S0365-05962019000100010
WOS:000457571600010
S0365-05962019000100010.pdf
url http://dx.doi.org/10.1590/abd1806-4841.20198070
http://hdl.handle.net/11449/185388
identifier_str_mv Anais Brasileiros De Dermatologia. Rio De Janeiro Rj: Soc Brasileira Dermatologia, v. 94, n. 1, p. 56-61, 2019.
0365-0596
10.1590/abd1806-4841.20198070
S0365-05962019000100010
WOS:000457571600010
S0365-05962019000100010.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Anais Brasileiros De Dermatologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 56-61
application/pdf
dc.publisher.none.fl_str_mv Soc Brasileira Dermatologia
publisher.none.fl_str_mv Soc Brasileira Dermatologia
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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